CAR-T Therapy Market Global Report 2020-30
April 2020
200
About the Report
About the Report
The CAR-T therapy market consists of sales of CAR-T therapy products and related services involved in providing CAR-T therapy to the cancer patients. The CAR-T therapy is an immunotherapy used to treat cancer by using patient's own cells. In this therapy, the white blood cells are infused with chimeric antigen receptor that modifies the T-type of white blood cells to fight against cancer cells.
The global CAR-T therapy market was worth USD 611.31 million in 2019. It is expected to grow at a compound annual growth rate (CAGR) of 51.10% and reach USD 3,186.23 million by 2023.
The CAR-T therapy market has been geographically segmented into North America, Western Europe, Asia-Pacific, Eastern Europe, South America and Middle East & Africa. North America is expected to be the largest region in the forecast period.
The CAR-T therapy market covered in this report is segmented by target antigen into CD19, CD22, others. It is also segmented by application into acute lymphoblastic leukaemia, diffuse large b-cell lymphoma, follicular lymphoma, chronic lymphocytic leukaemia, multiple myeloma, others.
The CAR-T therapy market is driven by the increasing financial support provided by different organizations to promote the development and consumption of CAR-T therapy. The government and non-government organizations provide financial support to the companies in CAR-T therapy market for research and development and to the patients for their treatment of acute lymphoblastic leukaemia (ALL). For instance, in 2019, the Ministry of Business, Innovation and Employment of New Zealand announced its contribution of USD 4.9 million over 5 years to its partnership scheme with Malaghan Institute (MI), in order to support the development of CAR T-cell manufacturing in New Zealand. Further, governments in some countries provide subsidy to patients undergoing CAR-T therapy owing to the high cost of the treatment. For example, in 2019, the government of Australia included the CAR-T therapy on the Medicare Benefits Schedule (MBS). The inclusion of (Kymriah) CAR-T therapy in MBS reduces the cost of the treatment for almost 30 paediatric and young adult (ALL) patients per year in Australia. The financial support provided by different organizations towards CAR-T therapy positively drives the growth of CAR-T therapy market.
The limitations on the application of CAR-T therapy limits the growth of the market. The limitations on CAR-T therapy includes its failure to treat other types of cancer, side effects and the high cost of treatment. CAR-T therapy is widely used as a treatment for a particular type of blood cancer and fails to treat other types of cancers such as lung cancer or breast cancer. Further, in many cases the application of CAR-T therapy results in cytokine release syndrome (CRS). CRS is severe flu like condition causing high fever, nausea, chills, headache, rash, and troubled breathing. Further, the high cost limits the growth of the market. According to an article in HealthLeaders in 2019, the cost of one CAR-T therapy session can be up to USD 375,000 excluding the overhead charges such as hospital bills. Thus, the growth of the CAR-T therapy is restricted by the various limitations on the application of CAR-T therapy.
The companies in the CAR-T therapy market are conducting clinical trials to assess the ability of CAR-T therapy to treat multiple myeloma. Multiple myeloma is a type of white blood cell cancer where the cancer cells accumulate in the bone marrow and surrounds the healthy blood cells. CAR-T therapy is being tested as a treatment for multiple myeloma. CAR-T cells are modified to target the multiple myeloma causing cells to treat the relapsed or refractory multiple myeloma (RRMM). For instance, Sorrento Therapeutics, a USA based developer of therapeutic approaches to treat different types of cancer, developed CAR2 anti-CD38 CAR-T cell therapy to treat RRMM. The CAR2 anti-CD38 CAR-T cell therapy is in phase 1 of its clinical trial with 72 participant recruitments made by the end of 2019.The aim of the clinical trial is to evaluate the efficiency and safety of CAR2 anti-CD38 CAR-T cell therapy. The trial is expected to be completed in 2020.
In 2019, Novartis, a Switzerland based global medicines company, acquired CellforCure for an undisclosed amount. The acquisition is aimed to increase Novartis' internal production capacity for cell and gene therapies. CellforCure is a French based contract development and manufacturing organization (CDMO) that provides manufacturing facility for cell and gene therapy. CellforCure assisted Novartis in 2017 to manufacture CAR-T treatment named Kymriah.
Major players in the market are Novartis AG, Kite Pharma, Pfizer Inc, Juno Therapeutics, Celgene Corporation, CARsgen Therapeutics, Sorrento Therapeutics and Legend Biotech.
Products
Products
1) By Target Antigen: CD19; CD22; Others; 2) By Application: Acute Lymphoblastic Leukemia; Diffuse Large B-Cell Lymphoma; Follicular Lymphoma; Chronic Lymphocytic Leukemia; Multiple Myeloma; Others
Companies
Novartis AG; Kite Pharma; Pfizer Inc;; Juno Therapeutics; Celgene Corporation;; CARsgen Therapeutics; Sorrento Therapeutics; Legend Biotech; Mustang Bio; Immune Therapeutics; Atara Biotherapeutics; Aurora Biopharma Inc.; Eureka Therapeutics; Autolus; TILT Biotherapeutics; Fortress Biotech.; Autolus Therapeutics PLC; bluebird bio; Carina Biotech;; CARTherics; Endocyte, Inc.; F1 Oncology, Inc.; Fate Therapeutics Inc.; Gilead; Oxford BioMedica PLC.; PeproMene Bio Inc.; Tessa Therapeutics Pte Ltd.; TILT Biotherapeutics Ltd.
Table of Contents
Table of Contents
1. Executive Summary
2. CAR-T therapy Market Characteristics
3. CAR-T therapy Market Size And Growth
3.1. Global CAR-T therapy Historic Market, 2015-2019, USD Billion
3.1.1. Drivers Of The Market
3.1.2. Restraints On The Market
3.2. Global CAR-T therapy Forecast Market, 2019-2023F, 2025F, 2030F, USD Billion
3.2.1. Drivers Of The Market
3.2.2. Restraints On the Market
4. CAR-T therapy Market Segmentation
4.1. Global CAR-T therapy Market, Segmentation By Target Antigen, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
CD19
CD22
Others
4.2. Global CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Acute Lymphoblastic Leukemia
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Chronic Lymphocytic Leukemia
Multiple Myeloma
Others
5. CAR-T therapy Market Regional And Country Analysis
5.1. Global CAR-T therapy Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
5.2. Global CAR-T therapy Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
6. Asia-Pacific CAR-T therapy Market
6.1. Asia-Pacific CAR-T therapy Market Overview
6.2. Asia-Pacific CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
7. China CAR-T therapy Market
7.1. China CAR-T therapy Market Overview
7.2. China CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F,USD Billion
8. India CAR-T therapy Market
8.1. India CAR-T therapy Market Overview
8.2. India CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
9. Japan CAR-T therapy Market
9.1. Japan CAR-T therapy Market Overview
9.2. Japan CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
10. Australia CAR-T therapy Market
10.1. Australia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
11. Indonesia CAR-T therapy Market
11.1. Indonesia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
12. South Korea CAR-T therapy Market
12.1. South Korea CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
13. Western Europe CAR-T therapy Market
13.1. Western Europe CAR-T therapy Market Overview
13.2. Western Europe CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
14. UK CAR-T therapy Market
14.1. UK CAR-T therapy Market Overview
14.2. UK CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
15. Germany CAR-T therapy Market
15.1. Germany CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
16. France CAR-T therapy Market
16.3. France CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
17. Eastern Europe CAR-T therapy Market
17.1. Eastern Europe CAR-T therapy Market Overview
17.2. Eastern Europe CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
18. Russia CAR-T therapy Market
18.1. Russia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
19. North America CAR-T therapy Market
19.1. North America CAR-T therapy Market Overview
19.2. North America CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
20. USA CAR-T therapy Market
20.1. USA CAR-T therapy Market Overview
20.2. USA CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
21. South America CAR-T therapy Market
21.1. South America CAR-T therapy Market Overview
21.2. South America CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
22. Brazil CAR-T therapy Market
22.1. Brazil CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
23. Middle East CAR-T therapy Market
23.1. Middle East CAR-T therapy Market Overview
23.2. Middle East CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
24. Africa CAR-T therapy Market
24.1. Africa CAR-T therapy Market Overview
24.2. Africa CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
25. CAR-T therapy Market Competitive Landscape And Company Profiles
25.1. CAR-T therapy Market Competitive Landscape
25.2. CAR-T therapy Market Company Profiles
25.2.1. Novartis AG
25.2.1.1. Overview
25.2.1.2. Products and Services
25.2.1.3. Strategy
25.2.1.4. Financial Performance
25.2.2. Kite Pharma
25.2.2.1. Overview
25.2.2.2. Products and Services
25.2.2.3. Strategy
25.2.2.4. Financial Performance
25.2.3. Pfizer Inc
25.2.3.1. Overview
25.2.3.2. Products and Services
25.2.3.3. Strategy
25.2.3.4. Financial Performance
25.2.4. Juno Therapeutics
25.2.4.1. Overview
25.2.4.2. Products and Services
25.2.4.3. Strategy
25.2.4.4. Financial Performance
25.2.5. Celgene Corporation
25.2.5.1. Overview
25.2.5.2. Products and Services
25.2.5.3. Strategy
25.2.5.4. Financial Performance
26. Key Mergers And Acquisitions In The CAR-T therapy Market
27. CAR-T therapy Market Trends And Strategies
28. CAR-T therapy Market Future Outlook and Potential Analysis
29. Appendix
29.1. Abbreviations
29.2. Currencies
29.3. Research Inquiries
29.4. The Business Research Company
29.5. Copyright And Disclaimer
List of Figure
Figure 1: Global Historic Market Growth, 2015-2019, USD Billion
Figure 2: Global Forecast Market Growth, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 3: Global CAR-T therapy Market, Segmentation By Target Antigen, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 4: Global CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 5: Global CAR-T therapy Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 6: Global CAR-T therapy Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 7: Asia-Pacific, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 8: China, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 9: India, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 10: Japan, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 11: Australia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 12: Indonesia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 13: South Korea, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 14: Western Europe, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 15: UK, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 16: Germany, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 17: France, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 18: Eastern Europe, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 19: Russia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 20: North America, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 21: USA, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 22: South America, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 23: Brazil, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 24: Middle East, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 25: Africa, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Figure 26: Novartis AG Financial Performance
Figure 27: Kite Pharma Financial Performance
Figure 28: Pfizer Inc Financial Performance
Figure 29: Juno Therapeutics Financial Performance
Figure 30: Celgene Corporation Financial Performance
List of Table
Table 1: Global Historic Market Growth, 2015-2019, USD Billion
Table 2: Global Forecast Market Growth, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 3: Global CAR-T therapy Market, Segmentation By Target Antigen, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 4: Global CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 5: Global CAR-T therapy Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 6: Global CAR-T therapy Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 7: Asia-Pacific, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 8: China, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 9: India, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 10: Japan, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 11: Australia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 12: Indonesia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 13: South Korea, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 14: Western Europe, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 15: UK, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 16: Germany, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 17: France, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 18: Eastern Europe, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 19: Russia, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 20: North America, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 21: USA, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 22: South America, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 23: Brazil, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 24: Middle East, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 25: Africa, CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion
Table 26: Novartis AG Financial Performance
Table 27: Kite Pharma Financial Performance
Table 28: Pfizer Inc Financial Performance
Table 29: Juno Therapeutics Financial Performance
Table 30: Celgene Corporation Financial Performance
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