Cardiovascular Prosthetic Devices - Medical Devices Pipeline Assessment, 2018

Cardiovascular Prosthetic Devices - Medical Devices Pipeline Assessment, 2018


  • Products Id :- GDME0591EPD
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Executive Summary

Cardiovascular Prosthetic Devices-Medical Devices Pipeline Assessment, 2018

Summary

GlobalData's Medical Devices sector report, Cardiovascular Prosthetic Devices-Medical Devices Pipeline Assessment, 2018 provides an overview of Cardiovascular Prosthetic Devices currently in pipeline stage.

The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and, the number of trials for the key Cardiovascular Prosthetic Devices pipeline products.

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

*Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

Scope

- Extensive coverage of the Cardiovascular Prosthetic Devices under development

- The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

- The report reviews the major players involved in the development of Cardiovascular Prosthetic Devices and list all their pipeline projects

- The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

- The report provides key clinical trial data of ongoing trials specific to pipeline products

- Recent developments in the segment / industry

Reasons to buy

The report enables you to-

- Formulate significant competitor information, analysis, and insights to improve R&D strategies

- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

- Identify and understand important and diverse types of Cardiovascular Prosthetic Devices under development

- Develop market-entry and market expansion strategies

- Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

- In-depth analysis of the product's current stage of development, territory and estimated launch date



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1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 7

1.2 List of Figures 14

2 Introduction 15

2.1 Cardiovascular Prosthetic Devices Overview 15

3 Products under Development 16

3.1 Cardiovascular Prosthetic Devices-Pipeline Products by Stage of Development 16

3.2 Cardiovascular Prosthetic Devices-Pipeline Products by Segment 17

3.3 Cardiovascular Prosthetic Devices-Pipeline Products by Territory 18

3.4 Cardiovascular Prosthetic Devices-Pipeline Products by Regulatory Path 19

3.5 Cardiovascular Prosthetic Devices-Pipeline Products by Estimated Approval Date 20

3.6 Cardiovascular Prosthetic Devices-Ongoing Clinical Trials 21

4 Cardiovascular Prosthetic Devices-Pipeline Products under Development by Companies 22

4.1 Cardiovascular Prosthetic Devices Companies-Pipeline Products by Stage of Development 22

4.2 Cardiovascular Prosthetic Devices-Pipeline Products by Stage of Development 25

5 Cardiovascular Prosthetic Devices Companies and Product Overview 28

5.1 4Tech Cardio Ireland Ltd Company Overview 28

5.2 Abbott Vascular Inc Company Overview 31

5.3 Admedus Ltd Company Overview 34

5.4 Ample Medical Inc Company Overview 35

5.5 Ancora Heart Inc Company Overview 36

5.6 Aporo Biomedical, Inc. (Inactive) Company Overview 39

5.7 BioStable Science & Engineering, Inc. Company Overview 40

5.8 BioVentrix Inc Company Overview 41

5.9 CARAG AG Company Overview 44

5.10 Cardiac Dimensions Inc Company Overview 47

5.11 Cardiosolutions Inc Company Overview 50

5.12 Celyad SA Company Overview 51

5.13 Children's Hospital Boston Company Overview 54

5.14 Cierra, Inc. (Inactive) Company Overview 56

5.15 CollPlant Ltd Company Overview 57

5.16 coramaze technologies GmbH Company Overview 58

5.17 CoreMedic AG Company Overview 59

5.18 Coroneo Inc. Company Overview 62

5.19 CUBE SRL Company Overview 63

5.20 Daidalos Solutions BV Company Overview 64

5.21 Dextera Surgical Inc Company Overview 66

5.22 Edwards Lifesciences Corp Company Overview 67

5.23 Emory University Company Overview 74

5.24 Ension, Inc. Company Overview 76

5.25 Georgia Institute of Technology Company Overview 77

5.26 Hangzhou DeJin Medtech Co Ltd Company Overview 78

5.27 Kardium Inc Company Overview 80

5.28 Kephalios SAS Company Overview 81

5.29 Lartim Medical Ltd Company Overview 82

5.30 Lifetech Scientific (Shenzhen) Co Ltd Company Overview 83

5.31 LivaNova PLC Company Overview 89

5.32 Mardil Medical, Inc. Company Overview 91

5.33 Mayo Clinic Company Overview 94

5.34 Medtentia International Ltd Oy Company Overview 95

5.35 MiCardia Corp Company Overview 97

5.36 Michigan Critical Care Consultants, Inc. Company Overview 98

5.37 Micro Interventional Devices, Inc. Company Overview 100

5.38 Millipede LLC Company Overview 105

5.39 Mitral Heal Company Overview 108

5.40 Mitralign Inc Company Overview 109

5.41 Mitralix Ltd. Company Overview 112

5.42 Mitre Medical Corp Company Overview 113

5.43 MVRx, Inc. Company Overview 115

5.44 Neochord Inc Company Overview 118

5.45 North Carolina State University Company Overview 122

5.46 Occlutech International AB Company Overview 123

5.47 Phoenix Cardiac Devices, Inc. Company Overview 125

5.48 Rambam Health Care Campus Company Overview 128

5.49 ReCor Medical Inc Company Overview 129

5.50 SCR, Inc. Company Overview 130

5.51 SeptRx, Inc. (Inactive) Company Overview 131

5.52 St. Jude Medical LLC Company Overview 132

5.53 Strait Access Technologies (Pty) Ltd Company Overview 138

5.54 Sutura, Inc. (Inactive) Company Overview 139

5.55 Swissimplant AG (Inactive) Company Overview 140

5.56 Symetis SA Company Overview 141

5.57 Tel Aviv Sourasky Medical Center Company Overview 142

5.58 TransCardiac Therapeutics, LLC Company Overview 143

5.59 TTK Healthcare Ltd Company Overview 144

5.60 University of Manitoba Company Overview 145

5.61 University of Minnesota Company Overview 146

5.62 University of South Carolina Company Overview 147

5.63 Valcare Medical Company Overview 148

5.64 Valtech Cardio Ltd Company Overview 152

5.65 Vanderbilt University Company Overview 161

5.66 Vascular Concepts Ltd Company Overview 162

5.67 Viacor Inc Company Overview 163

5.68 W. L. Gore & Associates Inc Company Overview 164

6 Cardiovascular Prosthetic Devices- Recent Developments 168

6.1 May 24, 2018: Real-World Study Results Support Use of Abbott s AMPLATZER Amulet to Reduce Stroke in Patients Suffering from Atrial Fibrillation Without the Need for Lifetime Blood Thinners 168

6.2 May 24, 2018: Medtronic Reports Fourth Quarter And Fiscal Year 2018 Financial Results 169

6.3 May 24, 2018: CollPlant Announces First Quarter 2018 Financial Results 171

6.4 May 21, 2018: Edwards Announces Key Events For EuroPCR 2018 173

6.5 May 16, 2018: First patient treated in First-in-Man study of CoreMedic's ChordArt mitral valve repair system 174

6.6 May 14, 2018: Ancora Heart Expands Enrollment of U.S. Early Feasibility Study for the AccuCinch System for Left Ventricular Repair 175

6.7 May 08, 2018: Cardiac Dimensions Announces Appointment of Dr. Matthew Stark as Vice President of Clinical and Regulatory Affairs, Adds New Board Member 176

6.8 May 08, 2018: Corindus Announces First Quarter 2018 Financial Results 177

6.9 May 07, 2018: Medtronic Appoints Mike Weinstein As Senior Vice President Of Strategy 178

6.10 May 02, 2018: Solvay's tough, biocompatible Radel PPSU selected for valve sizers in BioStable Science & Engineering's HAART 300 aortic annuloplasty kit 178

6.11 May 02, 2018: CryoLife Announces First Quarter 2018 Financial Results 179

6.12 Apr 30, 2018: Edwards Granted CE Mark For First Transcatheter Tricuspid Therapy 180

6.13 Apr 30, 2018: Neochord DS1000 System Successfully Treats 20th Patient in Combination with Other Beating Heart Procedures 181

6.14 Apr 26, 2018: Expanded Registry Data Shows Continued Positive Results For The Mitraclip Device 181

6.15 Apr 25, 2018: Minimally Invasive Investigational Procedure Treats Mitral Regurgitation as an Alternative to Open Heart Surgery 182

6.16 Apr 25, 2018: LeMaitre Q1 2018 Sales USD26.0mm (+8%), EPS USD0.19 (+17%) 183

6.17 Apr 25, 2018: Xianjian Technology Receives the Most Attention from Institutional Investors 184

6.18 Apr 24, 2018: Edwards Lifesciences Announces First Quarter 2018 Financial Results 184

6.19 Apr 20, 2018: Cook Medical Appoints Christina Anne Vice President of Distribution Channel Management 186

6.20 Apr 18, 2018: HeartStitch Announces CE Mark For CoAp Pro Mitral Valve Repair 186

6.21 Apr 12, 2018: CollPlant Appoints Revital Mandil-Levin as Chief Business Development Officer 187

6.22 Apr 05, 2018: Dr. Laura Mauri to Join Medtronic as Vice President, Global Clinical Research & Analytics 188

6.23 Apr 03, 2018: FDA Approves GORE CARDIOFORM Septal Occluder for PFO Closure to Prevent Recurrent Ischemic Stroke 188

6.24 Mar 29, 2018: Northwestern Memorial Hospital Surgeon First in Illinois to Repair Aortic Valve with Novel Ring 189

6.25 Mar 23, 2018: 2017 fiscal year: B. Braun increases sales and earnings, with investments of one billion euros 190

6.26 Mar 21, 2018: CollPlant Reports Fourth Quarter and Year End 2017 Financial Results and Provides Business Update 192

6.27 Mar 19, 2018: Abbott's MitraClip Therapy Receives National Reimbursement in Japan to Treat Patients with Mitral Regurgitation 194

6.28 Mar 14, 2018: Corindus Reports Fourth Quarter and Full Year 2017 Results 195

6.29 Mar 12, 2018: BioVentrix Announces First Patient at Cardiovascular Institute of the South Successfully Treated in IDE Study of Revivent TC TransCatheter Ventricular Enhancement Treatment 196

6.30 Mar 07, 2018: CryoLife Reports Fourth Quarter and Full Year 2017 Results 196

6.31 Feb 28, 2018: LivaNova Announces Fourth Quarter and Full-Year 2017 Results 198

6.32 Feb 22, 2018: Tricuspid Valve Repair Company 4Tech Appoints Tom Fleming as President and CEO, and Dr. Keith Dawkins as CMO 200

6.33 Feb 22, 2018: Tricuspid Valve Repair Company 4Tech Appoints Tom Fleming as President and CEO, and Dr. Keith Dawkins as CMO 200

6.34 Feb 21, 2018: LeMaitre Reports Net Income Of USD4.3mm In Q4 2017 201

6.35 Feb 13, 2018: Four start-ups chosen for the B. Braun Accelerator Program 202

6.36 Feb 07, 2018: Caisson Interventional Expanding in Maple Grove 202

6.37 Feb 06, 2018: BioVentrix Achieves 2018 NUB Reimbursement Status 1 in Germany for Revivent TC TransCatheter Ventricular Enhancement System 203

6.38 Feb 01, 2018: Successful Clinical Application of China's First Transcatheter Mitral Valve Repair Device, MitralStitch 204

6.39 Feb 01, 2018: Edwards Lifesciences Reports Fourth Quarter Results 204

6.40 Jan 30, 2018: Alex Gu Named Senior Vice President and President of Medtronic's Greater China Region 206

6.41 Jan 29, 2018: Mardil Medical Appoints Martin Madden to Board of Directors 207

6.42 Jan 18, 2018: KEPHALIOS reports first patient implanted with Kalios, its breakthrough mitral valve repair device 207

6.43 Jan 16, 2018: CollPlant Appoints David Tsur as Chairman of the Board 208

6.44 Jan 08, 2018: Dongguan Kewei Attends 17th National Thoracic and Cardiovascular Surgery Congress 209

6.45 Jan 08, 2018: LivaNova Announces Matthew J. Dodds as Senior Vice President, Corporate Development 209

6.46 Jan 07, 2018: LifeTech Scientific and Ally Bridge Group Form China-Global Medtech Investment and Operating Partnership 210

7 Appendix 266

7.1 Methodology 266

7.2 About GlobalData 269

7.3 Contact Us 269

7.4 Disclaimer 269

1.2 List of Figures

Figure 1: Cardiovascular Prosthetic Devices-Pipeline Products by Stage of Development 17

Figure 2: Cardiovascular Prosthetic Devices-Pipeline Products by Segment 18

Figure 3: Cardiovascular Prosthetic Devices-Pipeline Products by Territory 19

Figure 4: Cardiovascular Prosthetic Devices-Pipeline Products by Regulatory Path 20

Figure 5: Cardiovascular Prosthetic Devices-Pipeline Products by Estimated Approval Date 21

Figure 6: Cardiovascular Prosthetic Devices-Ongoing Clinical Trials 22

1.1 List of Tables

Table 1: Cardiovascular Prosthetic Devices-Pipeline Products by Stage of Development 17

Table 2: Cardiovascular Prosthetic Devices-Pipeline Products by Segment 18

Table 3: Cardiovascular Prosthetic Devices-Pipeline Products by Territory 19

Table 4: Cardiovascular Prosthetic Devices-Pipeline Products by Regulatory Path 20

Table 5: Cardiovascular Prosthetic Devices-Pipeline Products by Estimated Approval Date 21

Table 6: Cardiovascular Prosthetic Devices-Ongoing Clinical Trials 22

Table 7: Cardiovascular Prosthetic Devices Companies-Pipeline Products by Stage of Development 23

Table 8: Cardiovascular Prosthetic Devices-Pipeline Products by Stage of Development 26

Table 9: 4Tech Cardio Ireland Ltd Pipeline Products & Ongoing Clinical Trials Overview 29

Table 10: TriCinch System-Product Status 29

Table 11: TriCinch System-Product Description 29

Table 12: 4Tech Cardio Ireland Ltd-Ongoing Clinical Trials Overview 30

Table 13: TriCinch System-Clinical Trial Evaluation of the Percutaneous 4Tech TriCinch Coil Tricuspid Valve Repair System 31

Table 14: TriCinch System-International Multisite Transcatheter Tricuspid Valve Therapies Registry 31

Table 15: Abbott Vascular Inc Pipeline Products & Ongoing Clinical Trials Overview 32

Table 16: Transcatheter Tricuspid Valve Repair System-Product Status 32

Table 17: Transcatheter Tricuspid Valve Repair System-Product Description 32

Table 18: Abbott Vascular Inc-Ongoing Clinical Trials Overview 33

Table 19: Transcatheter Tricuspid Valve Repair System-Trial to Evaluate Treatment with Abbott Transcatheter Clip Repair System in Patients with Moderate or Greater Tricuspid Regurgitation: TRILUMINATE 34

Table 20: Admedus Ltd Pipeline Products & Ongoing Clinical Trials Overview 35

Table 21: 3D Curve-Product Status 35

Table 22: 3D Curve-Product Description 35

Table 23: Ample Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 36

Table 24: PS3 System-Product Status 36

Table 25: PS3 System-Product Description 36

Table 26: Ancora Heart Inc Pipeline Products & Ongoing Clinical Trials Overview 37

Table 27: AccuCinch Ventriculoplasty System-Product Status 37

Table 28: AccuCinch Ventriculoplasty System-Product Description 37

Table 29: Ancora Heart Inc-Ongoing Clinical Trials Overview 38

Table 30: AccuCinch Ventriculoplasty System-A Study of Percutaneous Treatment of Mitral Regurgitation Using the AccuCinch System 39

Table 31: Aporo Biomedical, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 40

Table 32: Patent Foramen Ovale Closure Device-Product Status 40

Table 33: Patent Foramen Ovale Closure Device-Product Description 40

Table 34: BioStable Science & Engineering, Inc. Pipeline Products & Ongoing Clinical Trials Overview 41

Table 35: HAART 200 Aortic Annuloplasty Device-Product Status 41

Table 36: HAART 200 Aortic Annuloplasty Device-Product Description 41

Table 37: BioVentrix Inc Pipeline Products & Ongoing Clinical Trials Overview 42

Table 38: Revivent-TC System-Product Status 42

Table 39: Revivent-TC System-Product Description 42

Table 40: BioVentrix Inc-Ongoing Clinical Trials Overview 43

Table 41: Revivent-TC System-Clinical Study of the BioVentrix Revivent TC for the Treatment of Ischemic Cardiomyopathy 44

Table 42: Revivent-TC System-Clinical Study of the BioVentrix Revivent TC System for Treatment of Left Ventricular Aneurysms 44

Table 43: CARAG AG Pipeline Products & Ongoing Clinical Trials Overview 45

Table 44: Solysafe Septal Occluder-Degradable Version-Product Status 45

Table 45: Solysafe Septal Occluder-Degradable Version-Product Description 45

Table 46: CARAG AG-Ongoing Clinical Trials Overview 46

Table 47: Solysafe Septal Occluder-Degradable Version-Prospective Single Center Pilot Clinical Study to Evaluate the Safety and Effectiveness of an Intracardiac Septal Closure Device with Biodegradable Framework in Patients with Clinically Significant Atrial Septum Defect (ASD) or Patent Foramen Ovale (PFO) 47

Table 48: Cardiac Dimensions Inc Pipeline Products & Ongoing Clinical Trials Overview 48

Table 49: CARILLON Mitral Contour System-Product Status 48

Table 50: CARILLON Mitral Contour System-Product Description 48

Table 51: Cardiac Dimensions Inc-Ongoing Clinical Trials Overview 49

Table 52: CARILLON Mitral Contour System-Assessment of the Carillon Mitral Contour System in Treating Functional Mitral Regurgitation Associated with Heart Failure 50

Table 53: CARILLON Mitral Contour System-The REDUCE FMR Trial: Safety and Efficacy of the CARILLON Mitral Contour System in Reducing Functional Mitral Regurgitation (FMR) Associated with Heart Failure 50

Table 54: Cardiosolutions Inc Pipeline Products & Ongoing Clinical Trials Overview 51

Table 55: Mitra-Spacer-Product Status 51

Table 56: Mitra-Spacer-Product Description 51

Table 57: Celyad SA Pipeline Products & Ongoing Clinical Trials Overview 52

Table 58: Cardiao3 Closure Device-Product Status 52

Table 59: Cardiao3 Closure Device-Product Description 52

Table 60: Heart Access Sheath-Mitral Valve Repair-Product Status 53

Table 61: Heart Access Sheath-Mitral Valve Repair-Product Description 53

Table 62: Mitral Valve Neo-chordae-Product Status 53

Table 63: Mitral Valve Neo-chordae-Product Description 54

Table 64: Children's Hospital Boston Pipeline Products & Ongoing Clinical Trials Overview 55

Table 65: Endovascular Prosthesis-Product Status 55

Table 66: Endovascular Prosthesis-Product Description 55

Table 67: Mitral Valve Repair Clip-Product Status 56

Table 68: Mitral Valve Repair Clip-Product Description 56

Table 69: Tricuspid Valve Repair Device-Product Status 56

Table 70: Tricuspid Valve Repair Device-Product Description 56

Table 71: Cierra, Inc. (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 57

Table 72: PFx Closure System-Product Status 57

Table 73: PFx Closure System-Product Description 57

Table 74: CollPlant Ltd Pipeline Products & Ongoing Clinical Trials Overview 58

Table 75: VergenixHVR-Product Status 58

Table 76: VergenixHVR-Product Description 58

Table 77: coramaze technologies GmbH Pipeline Products & Ongoing Clinical Trials Overview 59

Table 78: Mitramaze Valve Repair System-Product Status 59

Table 79: Mitramaze Valve Repair System-Product Description 59

Table 80: CoreMedic AG Pipeline Products & Ongoing Clinical Trials Overview 60

Table 81: ChordArt-Product Status 60

Table 82: ChordArt-Product Description 60

Table 83: CoreMedic AG-Ongoing Clinical Trials Overview 61

Table 84: ChordArt-First-in-man Chagall Study on Safety and Efficacy of ChordArt Mitral Valve Repair System 62

Table 85: Coroneo Inc. Pipeline Products & Ongoing Clinical Trials Overview 63

Table 86: Extra-Aortic Annuloplasty Ring-Product Status 63

Table 87: Extra-Aortic Annuloplasty Ring-Product Description 63

Table 88: CUBE SRL Pipeline Products & Ongoing Clinical Trials Overview 64

Table 89: Mitral-FERCube Ring-Product Status 64

Table 90: Mitral-FERCube Ring-Product Description 64

Table 91: Daidalos Solutions BV Pipeline Products & Ongoing Clinical Trials Overview 65

Table 92: Sutureless Mitral Valve Repair Ring-Product Status 65

Table 93: Sutureless Mitral Valve Repair Ring-Product Description 65

Table 94: Sutureless Tricuspid Valve Repair Ring-Product Status 66

Table 95: Sutureless Tricuspid Valve Repair Ring-Product Description 66

Table 96: Dextera Surgical Inc Pipeline Products & Ongoing Clinical Trials Overview 67

Table 97: PFO Closure Device-Product Status 67

Table 98: PFO Closure Device-Product Description 67

Table 99: Edwards Lifesciences Corp Pipeline Products & Ongoing Clinical Trials Overview 68

Table 100: Alterra Adaptive Prestent-Product Status 68

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4Tech Cardio Ireland Ltd

Abbott Vascular Inc

Admedus Ltd

Ample Medical Inc

Ancora Heart Inc

Aporo Biomedical, Inc.

BioStable Science & Engineering, Inc.

BioVentrix Inc

CARAG AG

Cardiac Dimensions Inc

Cardiosolutions Inc

Celyad SA

Children's Hospital Boston

Cierra, Inc.

CollPlant Ltd

coramaze technologies GmbH

CoreMedic AG

Coroneo Inc.

CUBE SRL

Daidalos Solutions BV

Dextera Surgical Inc

Edwards Lifesciences Corp

Emory University

Ension, Inc.

Georgia Institute of Technology

Hangzhou DeJin Medtech Co Ltd

Kardium Inc

Kephalios SAS

Lartim Medical Ltd

Lifetech Scientific (Shenzhen) Co Ltd

LivaNova PLC

Mardil Medical, Inc.

Mayo Clinic

Medtentia International Ltd Oy

MiCardia Corp

Michigan Critical Care Consultants, Inc.

Micro Interventional Devices, Inc.

Millipede LLC

Mitral Heal

Mitralign Inc

Mitralix Ltd.

Mitre Medical Corp

MVRx, Inc.

Neochord Inc

North Carolina State University

Occlutech International AB

Phoenix Cardiac Devices, Inc.

Rambam Health Care Campus

ReCor Medical Inc

SCR, Inc.

SeptRx, Inc.

St. Jude Medical LLC

Strait Access Technologies (Pty) Ltd

Sutura, Inc.

Swissimplant AG

Symetis SA

Tel Aviv Sourasky Medical Center

TransCardiac Therapeutics, LLC

TTK Healthcare Ltd

University of Manitoba

University of Minnesota

University of South Carolina

Valcare Medical

Valtech Cardio Ltd

Vanderbilt University

Vascular Concepts Ltd

Viacor Inc

W. L. Gore & Associates Inc

4Tech Cardio Ireland Ltd, TriCinch System; Abbott Vascular Inc, Transcatheter Tricuspid Valve Repair System; Admedus Ltd, 3D Curve; Ample Medical Inc, PS3 System; Ancora Heart Inc, AccuCinch Ventriculoplasty System; Aporo Biomedical, Inc. (Inactive), Patent Foramen Ovale Closure Device; BioStable Science &; Engineering, Inc., HAART 200 Aortic Annuloplasty Device; BioVentrix Inc, Revivent-TC System; CARAG AG, Solysafe Septal Occluder - Degradable Version; Cardiac Dimensions Inc, CARILLON Mitral Contour System; Cardiosolutions Inc, Mitra-Spacer; Celyad SA, Cardiao3 Closure Device; Celyad SA, Heart Access Sheath - Mitral Valve Repair; Celyad SA, Mitral Valve Neo-chordae; Children's Hospital Boston, Endovascular Prosthesis; Children's Hospital Boston, Mitral Valve Repair Clip; Children's Hospital Boston, Tricuspid Valve Repair Device; Cierra, Inc. (Inactive), PFx Closure System; CollPlant Ltd, VergenixHVR; coramaze technologies GmbH, Mitramaze Valve Repair System; CoreMedic AG, ChordArt; Coroneo Inc., Extra-Aortic Annuloplasty Ring; CUBE SRL, Mitral-FERCube Ring; Daidalos Solutions BV, Sutureless Mitral Valve Repair Ring; Daidalos Solutions BV, Sutureless Tricuspid Valve Repair Ring; Dextera Surgical Inc, PFO Closure Device; Edwards Lifesciences Corp, Alterra Adaptive Prestent; Edwards Lifesciences Corp, Coapsys; Edwards Lifesciences Corp, FORMA Tricuspid Repair System; Edwards Lifesciences Corp, MOBIUS Leaflet Repair System; Edwards Lifesciences Corp, MONARC Mitral Repair System; Emory University, MitraPlug; Emory University, MitraSurg; Ension, Inc., Atrial Septal Defect Correction Device; Georgia Institute of Technology, Tricuspid Annuloplasty Rings; Hangzhou DeJin Medtech Co Ltd, MitralStitch; Hangzhou DeJin Medtech Co Ltd, Second Generation Mitral Valve Repair Device; Hangzhou DeJin Medtech Co Ltd, Tricuspid Repair Device; Kardium Inc, Percutaneous Mitral Valve Regurgitation Device; Kephalios SAS, Mitral Annuloplasty Ring; Lartim Medical Ltd, Mitral Valve Repair Device; Lifetech Scientific (Shenzhen) Co Ltd, Absnow Absorbable Occluder; Lifetech Scientific (Shenzhen) Co Ltd, IrisFIT PFO Occluder; Lifetech Scientific (Shenzhen) Co Ltd, LAmbre LAA Closure System; LivaNova PLC , Percutaneous Mitral Valve Repair Device; LivaNova PLC , Percutaneous Mitral Valve Replacement Device; Mardil Medical, Inc., VenTouch Triad Targeted Ventricular Reshaping System; Mayo Clinic, Catheter-Based Mitral Valve Repair Device; Medtentia International Ltd Oy, CathHELIX; Medtentia International Ltd Oy, Double Helix Mitral Annuloplasty System; MiCardia Corp, enCorTC; Michigan Critical Care Consultants, Inc., Millipede Percutaneous Annuloplasty Ring; Michigan Critical Care Consultants, Inc., Percutaneous Mitral Annuloplasty Ring; Micro Interventional Devices, Inc., MIA Annuloplasty System - Mitral Valve Repair; Micro Interventional Devices, Inc., MIA Annuloplasty System - Tricuspid Valve Repair; Micro Interventional Devices, Inc., Patent Foramen Ovale Fixation Device; Millipede LLC, IRIS Transcatheter Annuloplasty Ring; Mitral Heal, Off-Pump Transapical Mitral Valve Device; Mitralign Inc, TriAlign Tricuspid Percutaneous Valve Annuloplasty System; Mitralix Ltd., Mistral; Mitre Medical Corp, Mitral Touch; Mitre Medical Corp, Next Generation Mitral Touch; MVRx, Inc., ARTO System; Neochord Inc, NeoChord DS1000; North Carolina State University, Transapical Mitral Valve Regurgitation Device; Occlutech International AB, Coronary Prosthesis Device; Occlutech International AB, Occlutech Figulla Flex UNI; Phoenix Cardiac Devices, Inc., BACE Device; Rambam Health Care Campus, Adjustable Annuloplasty Apparatus; ReCor Medical Inc, Ultrasound Catheter - Mitral Regurgitation; SCR, Inc., Chronic Implantable Counterpulsation Device; SeptRx, Inc. (Inactive), SeptRx IPO; St. Jude Medical LLC, Amplatzer Amulet Left Atrial Appendage Occluder; St. Jude Medical LLC, AMPLATZER Duct Occluder II AS; Strait Access Technologies (Pty) Ltd, Mitral Clip; Sutura, Inc. (Inactive), HeartStitch; Swissimplant AG (Inactive), Solysafe Septal Occluder - 10Fr Sheath; Symetis SA, Middle Peak Mitral Implant; Tel Aviv Sourasky Medical Center, Mitral Valve Implantation Device; TransCardiac Therapeutics, LLC, MitraFlex; TTK Healthcare Ltd, Mitral Annuloplasty Ring; University of Manitoba, Aortic Annular System; University of Minnesota, Bioresorbable Occlusion Device; University of South Carolina, Artificial Myocardium; Valcare Medical, AMEND Mitral Valve Repair System; Valcare Medical, Trivid; Valtech Cardio Ltd, Cardinal Adjustable Annuloplasty Ring System - Tricuspid Repair; Valtech Cardio Ltd, Cardioband System - Mitral Valve Repair; Valtech Cardio Ltd, Cardioband System - Tricuspid Regurgitation; Valtech Cardio Ltd, Transatrial Cardioband System; Valtech Cardio Ltd, V-Chordal System - Surgical; Valtech Cardio Ltd, V-Chordal System - Transfemoral; Vanderbilt University, Self Expanding Ductal Occluder; Vascular Concepts Ltd, VSD (Ventricular Septal Device); Viacor Inc, PTMA System; W. L. Gore &; Associates Inc, BioTREK; W. L. Gore &; Associates Inc, GORE HELEX Septal Occluder - PFO

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