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Acute Sensorineural Hearing Loss-Pipeline Review, H1 2015

Acute Sensorineural Hearing Loss-Pipeline Review, H1 2015


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Executive Summary

Acute Sensorineural Hearing Loss-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Acute Sensorineural Hearing Loss-Pipeline Review, H1 2015', provides an overview of the Acute Sensorineural Hearing Loss's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Acute Sensorineural Hearing Loss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Acute Sensorineural Hearing Loss and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Acute Sensorineural Hearing Loss

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Acute Sensorineural Hearing Loss and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Acute Sensorineural Hearing Loss products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Acute Sensorineural Hearing Loss pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Acute Sensorineural Hearing Loss

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Acute Sensorineural Hearing Loss pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Acute Sensorineural Hearing Loss Overview 6

Therapeutics Development 7

Pipeline Products for Acute Sensorineural Hearing Loss-Overview 7

Pipeline Products for Acute Sensorineural Hearing Loss-Comparative Analysis 8

Acute Sensorineural Hearing Loss-Therapeutics under Development by Companies 9

Acute Sensorineural Hearing Loss-Pipeline Products Glance 10

Late Stage Products 10

Clinical Stage Products 11

Early Stage Products 12

Acute Sensorineural Hearing Loss-Products under Development by Companies 13

Acute Sensorineural Hearing Loss-Companies Involved in Therapeutics Development 14

Nordmark Arzneimittel GmbH & Co. KG 14

Orbis Biosciences, Inc. 15

Otologic Pharmaceutics, Inc. 16

Pfizer Inc. 17

Sound Pharmaceuticals, Inc. 18

Xigen SA 19

Acute Sensorineural Hearing Loss-Therapeutics Assessment 20

Assessment by Monotherapy Products 20

Assessment by Combination Products 21

Assessment by Target 22

Assessment by Mechanism of Action 24

Assessment by Route of Administration 26

Assessment by Molecule Type 28

Drug Profiles 30

(acetylcysteine + disufenton sodium)-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

ancrod-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

betamethasone valerate-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

PF-04958242-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Small Molecules to Inhibit Gamma Secretase for Sensorineural Hearing Loss-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

SPI-1005-Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

Stem Cell Therapy for Sensorineural Hearing Loss-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

XG-102-Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

Acute Sensorineural Hearing Loss-Recent Pipeline Updates 42

Acute Sensorineural Hearing Loss-Product Development Milestones 45

Featured News & Press Releases 45

Nov 19, 2014: Otologic Pharmaceutics Initiates Phase 1 Clinical Study of NHPN-1010 for Hearing Disorders 45

Feb 18, 2014: Sound Pharmaceuticals submits positive Phase 2 clinical trial data on SPI-1005 for the prevention and treatment of sensorineural hearing loss 45

Dec 05, 2012: University Of Florida Begins Phase-II Trial With Sound Pharma's SPI-1005 To Prevent Hearing Loss 46

Nov 13, 2012: Auris Medical Announces Positive Results From Phase IIb Trial With AM-111 For Treatment Of Acute Sensorineural Hearing Loss 46

Apr 20, 2012: Auris Medical Completes Enrolment In Phase IIb Trial With AM-111 For Treatment Of Acute Sensorineural Hearing Loss 47

Appendix 48

Methodology 48

Coverage 48

Secondary Research 48

Primary Research 48

Expert Panel Validation 48

Contact Us 49

Disclaimer 49

List of Tables

Number of Products under Development for Acute Sensorineural Hearing Loss, H1 2015 7

Number of Products under Development for Acute Sensorineural Hearing Loss-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Late Stage Development, H1 2015 10

Comparative Analysis by Clinical Stage Development, H1 2015 11

Comparative Analysis by Early Stage Development, H1 2015 12

Products under Development by Companies, H1 2015 13

Acute Sensorineural Hearing Loss-Pipeline by Nordmark Arzneimittel GmbH & Co. KG, H1 2015 14

Acute Sensorineural Hearing Loss-Pipeline by Orbis Biosciences, Inc., H1 2015 15

Acute Sensorineural Hearing Loss-Pipeline by Otologic Pharmaceutics, Inc., H1 2015 16

Acute Sensorineural Hearing Loss-Pipeline by Pfizer Inc., H1 2015 17

Acute Sensorineural Hearing Loss-Pipeline by Sound Pharmaceuticals, Inc., H1 2015 18

Acute Sensorineural Hearing Loss-Pipeline by Xigen SA, H1 2015 19

Assessment by Monotherapy Products, H1 2015 20

Assessment by Combination Products, H1 2015 21

Number of Products by Stage and Target, H1 2015 23

Number of Products by Stage and Mechanism of Action, H1 2015 25

Number of Products by Stage and Route of Administration, H1 2015 27

Number of Products by Stage and Molecule Type, H1 2015 29

Acute Sensorineural Hearing Loss Therapeutics-Recent Pipeline Updates, H1 2015 42

List of Figures

Number of Products under Development for Acute Sensorineural Hearing Loss, H1 2015 7

Number of Products under Development for Acute Sensorineural Hearing Loss-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 11

Comparative Analysis by Early Stage Products, H1 2015 12

Assessment by Monotherapy Products, H1 2015 20

Number of Products by Top 10 Targets, H1 2015 22

Number of Products by Stage and Top 10 Targets, H1 2015 22

Number of Products by Top 10 Mechanism of Actions, H1 2015 24

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 24

Number of Products by Top 10 Routes of Administration, H1 2015 26

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 26

Number of Products by Top 10 Molecule Types, H1 2015 28

Number of Products by Stage and Top 10 Molecule Types, H1 2015 28

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Nordmark Arzneimittel GmbH & Co. KG

Orbis Biosciences, Inc.

Otologic Pharmaceutics, Inc.

Pfizer Inc.

Sound Pharmaceuticals, Inc.

Xigen SA

Acute Sensorineural Hearing Loss Therapeutic Products under Development, Key Players in Acute Sensorineural Hearing Loss Therapeutics, Acute Sensorineural Hearing Loss Pipeline Overview, Acute Sensorineural Hearing Loss Pipeline, Acute Sensorineural Hearing Loss Pipeline Assessment


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