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Advaxis, Inc.-Product Pipeline Review-2015

Advaxis, Inc.-Product Pipeline Review-2015

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Executive Summary

Advaxis, Inc.-Product Pipeline Review-2015


Global Markets Direct's, 'Advaxis, Inc.-Product Pipeline Review-2015', provides an overview of the Advaxis, Inc.'s pharmaceutical research and development focus.

This report provides comprehensive information on the current therapeutic developmental pipeline of Advaxis, Inc.'s, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.


The report provides brief overview of Advaxis, Inc. including business description, key information and facts, and its locations and subsidiaries

The report reviews current pipeline of Advaxis, Inc.'s human therapeutic division and enlists all their major and minor projects

The report features product description and descriptive mechanism of action for key pipeline products along with the product's developmental history and major milestones

Special feature on out-licensed and partnered product portfolio

The report summarizes all the dormant and discontinued pipeline projects

Latest company statement

Latest news and deals relating to the Advaxis, Inc.'s pipeline products

Reasons To Buy

Evaluate Advaxis, Inc.'s strategic position with total access to detailed information on its product pipeline

Assess the growth potential of Advaxis, Inc. in its therapy areas of focus

Identify new drug targets and therapeutic classes in the Advaxis, Inc.'s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas

Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps

Develop strategic initiatives by understanding the focus areas of Advaxis, Inc. and exploit collaboration and partnership opportunities

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Plan mergers and acquisitions effectively by identifying the most promising pipeline of Advaxis, Inc.

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Explore the dormant and discontinued projects of Advaxis, Inc. and identify potential opportunities in those areas

Avoid Intellectual Property Rights related issues

Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 5

Advaxis, Inc. Snapshot 6

Advaxis, Inc. Overview 6

Key Information 6

Key Facts 6

Advaxis, Inc.-Research and Development Overview 7

Key Therapeutic Areas 7

Advaxis, Inc.-Pipeline Review 10

Pipeline Products by Stage of Development 10

Pipeline Products-Monotherapy 11

Pipeline Products-Partnered Products 12

Partnered Products/Combination Treatment Modalities 13

Advaxis, Inc.-Pipeline Products Glance 14

Advaxis, Inc.-Clinical Stage Pipeline Products 14

Phase II Products/Combination Treatment Modalities 14

Phase I Products/Combination Treatment Modalities 15

Advaxis, Inc.-Early Stage Pipeline Products 16

IND/CTA Filed Products/Combination Treatment Modalities 16

Preclinical Products/Combination Treatment Modalities 17

Advaxis, Inc.-Drug Profiles 18


Product Description 18

Mechanism of Action 18

R&D Progress 18


Product Description 21

Mechanism of Action 21

R&D Progress 21


Product Description 23

Mechanism of Action 23

R&D Progress 23

Adxs-LmddA159 24

Product Description 24

Mechanism of Action 24

R&D Progress 24

Lm-LLO-CA9 26

Product Description 26

Mechanism of Action 26

R&D Progress 26

Lm-LLO-CD105A 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

Lm-LLO-Flk1 30

Product Description 30

Mechanism of Action 30

R&D Progress 30


Product Description 32

Mechanism of Action 32

R&D Progress 32

Lm-LLO-ISG15 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Lovaxin S 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

Vaccine to Target CEA for Ovarian Cancer 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

Vaccine to Target FAP for Breast and Colorectal Cancer 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

Vaccine to Target HER2 and CA9 for Breast Cancer 41

Product Description 41

Mechanism of Action 41

R&D Progress 41

Vaccine to Target Her2 and HMWMAA for Breast Cancer 43

Product Description 43

Mechanism of Action 43

R&D Progress 43

Vaccine to Target IL-13R Alpha2 for Solid Tumor 45

Product Description 45

Mechanism of Action 45

R&D Progress 45

Vaccine to Target PSA and HMWMAA for Prostate Cancer 47

Product Description 47

Mechanism of Action 47

R&D Progress 47

Vaccine to Target PSCA for Prostate Cancer 49

Product Description 49

Mechanism of Action 49

R&D Progress 49

Vaccine to Target WT1 for Lung Cancer 51

Product Description 51

Mechanism of Action 51

R&D Progress 51

Advaxis, Inc.-Pipeline Analysis 53

Advaxis, Inc.-Pipeline Products by Target 53

Advaxis, Inc.-Pipeline Products by Route of Administration 55

Advaxis, Inc.-Pipeline Products by Molecule Type 56

Advaxis, Inc.-Recent Pipeline Updates 57

Advaxis, Inc.-Dormant Projects 69

Advaxis, Inc.-Company Statement 70

Advaxis, Inc.-Locations And Subsidiaries 75

Head Office 75

Appendix 76

Methodology 76

Coverage 76

Secondary Research 76

Primary Research 76

Expert Panel Validation 76

Contact Us 76

Disclaimer 77

List of Tables

Advaxis, Inc., Key Information 6

Advaxis, Inc., Key Facts 6

Advaxis, Inc.-Pipeline by Indication, 2015 8

Advaxis, Inc.-Pipeline by Stage of Development, 2015 10

Advaxis, Inc.-Monotherapy Products in Pipeline, 2015 11

Advaxis, Inc.-Partnered Products in Pipeline, 2015 12

Advaxis, Inc.-Partnered Products/ Combination Treatment Modalities, 2015 13

Advaxis, Inc.-Phase II, 2015 14

Advaxis, Inc.-Phase I, 2015 15

Advaxis, Inc.-IND/CTA Filed, 2015 16

Advaxis, Inc.-Preclinical, 2015 17

Advaxis, Inc.-Pipeline by Target, 2015 54

Advaxis, Inc.-Pipeline by Route of Administration, 2015 55

Advaxis, Inc.-Pipeline by Molecule Type, 2015 56

Advaxis, Inc.-Recent Pipeline Updates, 2015 57

Advaxis, Inc.-Dormant Developmental Projects,2015 69

List of Figures

Advaxis, Inc.-Pipeline by Top 10 Indication, 2015 8

Advaxis, Inc.-Pipeline by Stage of Development, 2015 10

Advaxis, Inc.-Monotherapy Products in Pipeline, 2015 11

Advaxis, Inc.-Partnered Products in Pipeline, 2015 12

Advaxis, Inc.-Pipeline by Top 10 Target, 2015 53

Advaxis, Inc.-Pipeline by Top 10 Route of Administration, 2015 55

Advaxis, Inc.-Pipeline by Top 10 Molecule Type, 2015 56

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Current R&D Portfolio of Advaxis, Inc.; Advaxis, Inc. - Key Therapeutics; Advaxis, Inc. - Pipeline Overview and Promising Molecules; Advaxis, Inc. - News; Advaxis, Inc. - Latest Updates; Advaxis, Inc. - Pipeline; Advaxis, Inc. - Discontinued/Dormant Projects

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