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Artificial Pancreas-Pipeline Review

Artificial Pancreas-Pipeline Review


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Executive Summary

Artificial Pancreas-Pipeline Review, 2015

GlobalData's Medical Devices sector report, "Artificial Pancreas-Pipeline Review, 2015" provides an overview of Artificial Pancreas currently in pipeline stage.

The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and, the number of trials for the key Artificial Pancreas pipeline products.

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

Scope

Extensive coverage of the Artificial Pancreas products under development

The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

The report reviews the major players involved in the development of Artificial Pancreas and list all their pipeline projects

The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

The report provides key clinical trial data of ongoing trials specific to pipeline products

Recent developments in the segment / industry

Reasons To Buy

Formulate significant competitor information, analysis, and insights to improve R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of Artificial Pancreas under development

Develop market-entry and market expansion strategies

Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

In-depth analysis of the product's current stage of development, territory and estimated launch date

1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 4

1.2 List of Figures 7

2 Introduction 8

2.1 Artificial Pancreas Overview 8

3 Products under Development 9

3.1 Artificial Pancreas-Pipeline Products by Stage of Development 9

3.2 Artificial Pancreas-Pipeline Products by Territory 10

3.3 Artificial Pancreas-Pipeline Products by Regulatory Path 11

3.4 Artificial Pancreas-Pipeline Products by Estimated Approval Date 12

3.5 Artificial Pancreas-Ongoing Clinical Trials 13

4 Artificial Pancreas-Pipeline Products under Development by Companies 14

4.1 Artificial Pancreas Companies-Pipeline Products by Stage of Development 14

4.2 Artificial Pancreas-Pipeline Products by Stage of Development 16

5 Artificial Pancreas Companies and Product Overview 18

5.1 Advanced Biosensors-Ohio, Llc Company Overview 18

5.1.1 Advanced Biosensors-Ohio, Llc Pipeline Products & Ongoing Clinical Trials Overview 18

5.2 Animas Corporation Company Overview 19

5.2.1 Animas Corporation Pipeline Products & Ongoing Clinical Trials Overview 19

5.3 Beta-O2 Technologies Ltd. Company Overview 21

5.3.1 Beta-O2 Technologies Ltd. Pipeline Products & Ongoing Clinical Trials Overview 21

5.4 Bigfoot Biomedical, Inc. Company Overview 25

5.4.1 Bigfoot Biomedical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 25

5.5 BioTex, Inc. Company Overview 26

5.5.1 BioTex, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26

5.6 Boston University Company Overview 27

5.6.1 Boston University Pipeline Products & Ongoing Clinical Trials Overview 27

5.7 Cerco Medical Company Overview 28

5.7.1 Cerco Medical Pipeline Products & Ongoing Clinical Trials Overview 28

5.8 Converge Biotech, Inc. Company Overview 29

5.8.1 Converge Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 29

5.9 Covalor Medical, LLC Company Overview 30

5.9.1 Covalor Medical, LLC Pipeline Products & Ongoing Clinical Trials Overview 30

5.10 De Montfort University Company Overview 31

5.10.1 De Montfort University Pipeline Products & Ongoing Clinical Trials Overview 31

5.11 Defymed Company Overview 32

5.11.1 Defymed Pipeline Products & Ongoing Clinical Trials Overview 32

5.12 Diabeloop Company Overview 33

5.12.1 Diabeloop Pipeline Products & Ongoing Clinical Trials Overview 33

5.13 Dose Safety Inc. Company Overview 34

5.13.1 Dose Safety Inc. Pipeline Products & Ongoing Clinical Trials Overview 34

5.14 Imperial College London Company Overview 35

5.14.1 Imperial College London Pipeline Products & Ongoing Clinical Trials Overview 35

5.15 Inreda Diabetic BV Company Overview 39

5.15.1 Inreda Diabetic BV Pipeline Products & Ongoing Clinical Trials Overview 39

5.16 Kencak LLC Company Overview 40

5.16.1 Kencak LLC Pipeline Products & Ongoing Clinical Trials Overview 40

5.17 Medtronic plc Company Overview 41

5.17.1 Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 41

5.18 Miromatrix Medical Inc. Company Overview 48

5.18.1 Miromatrix Medical Inc. Pipeline Products & Ongoing Clinical Trials Overview 48

5.19 Pacific Diabetes Technologies, Inc. Company Overview 49

5.19.1 Pacific Diabetes Technologies, Inc. Pipeline Products & Ongoing Clinical Trials Overview 49

5.20 Pancreum, LLC Company Overview 50

5.20.1 Pancreum, LLC Pipeline Products & Ongoing Clinical Trials Overview 50

5.21 PharmaCyte Biotech, Inc. Company Overview 51

5.21.1 PharmaCyte Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 51

5.22 Rensselaer Polytechnic Institute Company Overview 53

5.22.1 Rensselaer Polytechnic Institute Pipeline Products & Ongoing Clinical Trials Overview 53

5.23 Schneider Children's Medical Center of Israel Company Overview 55

5.23.1 Schneider Children's Medical Center of Israel Pipeline Products & Ongoing Clinical Trials Overview 55

5.24 TecMed, Inc. Company Overview 57

5.24.1 TecMed, Inc. Pipeline Products & Ongoing Clinical Trials Overview 57

5.25 The University of Newcastle Company Overview 58

5.25.1 The University of Newcastle Pipeline Products & Ongoing Clinical Trials Overview 58

5.26 Ultradian Diagnostics LLC Company Overview 59

5.26.1 Ultradian Diagnostics LLC Pipeline Products & Ongoing Clinical Trials Overview 59

5.27 Universidad Autonoma de Madrid Company Overview 60

5.27.1 Universidad Autonoma de Madrid Pipeline Products & Ongoing Clinical Trials Overview 60

5.28 Universitat Politecnica de Valencia Company Overview 61

5.28.1 Universitat Politecnica de Valencia Pipeline Products & Ongoing Clinical Trials Overview 61

5.29 University of California, San Francisco Company Overview 62

5.29.1 University of California, San Francisco Pipeline Products & Ongoing Clinical Trials Overview 62

5.30 University of California, Santa Barbara Company Overview 63

5.30.1 University of California, Santa Barbara Pipeline Products & Ongoing Clinical Trials Overview 63

5.31 University of Cambridge Company Overview 65

5.31.1 University of Cambridge Pipeline Products & Ongoing Clinical Trials Overview 65

5.32 University of Florida Company Overview 66

5.32.1 University of Florida Pipeline Products & Ongoing Clinical Trials Overview 66

5.33 University of Virginia Company Overview 67

5.33.1 University of Virginia Pipeline Products & Ongoing Clinical Trials Overview 67

5.34 ViaCyte, Inc. Company Overview 71

5.34.1 ViaCyte, Inc. Pipeline Products & Ongoing Clinical Trials Overview 71

5.35 XERIS Pharmaceuticals, Inc. Company Overview 75

5.35.1 XERIS Pharmaceuticals, Inc. Pipeline Products & Ongoing Clinical Trials Overview 75

6 Artificial Pancreas-Recent Developments 76

7 Appendix 81

7.1 Methodology 81

7.2 About GlobalData 83

7.3 Contact Us 83

7.4 Disclaimer 83

1.2 List of Figures

Figure 1: Artificial Pancreas-Pipeline Products by Stage of Development 9

Figure 2: Artificial Pancreas-Pipeline Products by Territory 10

Figure 3: Artificial Pancreas-Pipeline Products by Regulatory Path 11

Figure 4: Artificial Pancreas-Pipeline Products by Estimated Approval Date 12

Figure 5: Artificial Pancreas-Ongoing Clinical Trials 13

1.1 List of Tables

Table 1: Artificial Pancreas-Pipeline Products by Stage of Development 9

Table 2: Artificial Pancreas-Pipeline Products by Territory 10

Table 3: Artificial Pancreas-Pipeline Products by Regulatory Path 11

Table 4: Artificial Pancreas-Pipeline Products by Estimated Approval Date 12

Table 5: Artificial Pancreas-Ongoing Clinical Trials 13

Table 6: Artificial Pancreas Companies-Pipeline Products by Stage of Development 14

Table 7: Artificial Pancreas-Pipeline Products by Stage of Development 16

Table 8: Advanced Biosensors-Ohio, Llc Pipeline Products & Ongoing Clinical Trials Overview 18

Table 9: Artificial Pancreas-Product Status 18

Table 10: Artificial Pancreas-Product Description 18

Table 11: Animas Corporation Pipeline Products & Ongoing Clinical Trials Overview 19

Table 12: Hypoglycemia-Hyperglycemia Minimizer System-Product Status 19

Table 13: Hypoglycemia-Hyperglycemia Minimizer System-Product Description 20

Table 14: Beta-O2 Technologies Ltd. Pipeline Products & Ongoing Clinical Trials Overview 21

Table 15: �Air-Product Status 21

Table 16: �Air-Product Description 22

Table 17: Beta-O2 Technologies Ltd.-Ongoing Clinical Trials Overview 23

Table 18: �Air-An Open Label, Pilot Investigation, to Assess the Safety and Efficacy of Transplantation of Macro-encapsulated Human Islets within the Bioartificial Pancreas Beta-Air in Patients with Type 1 Diabetes Mellitus 24

Table 19: Bigfoot Biomedical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 25

Table 20: Artificial Pancreas-Product Status 25

Table 21: Artificial Pancreas-Product Description 25

Table 22: BioTex, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26

Table 23: Artificial Pancreas-Product Status 26

Table 24: Artificial Pancreas-Product Description 26

Table 25: Boston University Pipeline Products & Ongoing Clinical Trials Overview 27

Table 26: Bionic Pancreas-Product Status 27

Table 27: Bionic Pancreas-Product Description 27

Table 28: Cerco Medical Pipeline Products & Ongoing Clinical Trials Overview 28

Table 29: Islet Sheet-Product Status 28

Table 30: Islet Sheet-Product Description 28

Table 31: Converge Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 29

Table 32: Bioartificial Pancreas System-Product Status 29

Table 33: Bioartificial Pancreas System-Product Description 29

Table 34: Covalor Medical, LLC Pipeline Products & Ongoing Clinical Trials Overview 30

Table 35: Artificial Pancreas-Product Status 30

Table 36: Artificial Pancreas-Product Description 30

Table 37: De Montfort University Pipeline Products & Ongoing Clinical Trials Overview 31

Table 38: InSmart Artificial Pancreas-Product Status 31

Table 39: InSmart Artificial Pancreas-Product Description 31

Table 40: Defymed Pipeline Products & Ongoing Clinical Trials Overview 32

Table 41: MAILPAN-Product Status 32

Table 42: MAILPAN-Product Description 32

Table 43: Diabeloop Pipeline Products & Ongoing Clinical Trials Overview 33

Table 44: Diabeloop-Product Status 33

Table 45: Diabeloop-Product Description 33

Table 46: Dose Safety Inc. Pipeline Products & Ongoing Clinical Trials Overview 34

Table 47: Dose Safety Controller-Product Status 34

Table 48: Dose Safety Controller-Product Description 34

Table 49: Imperial College London Pipeline Products & Ongoing Clinical Trials Overview 35

Table 50: Bio-inspired Artificial Pancreas-Product Status 35

Table 51: Bio-inspired Artificial Pancreas-Product Description 36

Table 52: Imperial College London-Ongoing Clinical Trials Overview 37

Table 53: Bio-inspired Artificial Pancreas-A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas 38

Table 54: Bio-inspired Artificial Pancreas-Closed-Loop Glucagon Administration for the Automated Prevention and Treatment of Hypoglycemia 38

Table 55: Bio-inspired Artificial Pancreas-The Summer Camp Study 2: Outpatient Automated Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas in a Pediatric Population Ages 6-11 at the Clara Barton Diabetes Camps 38

Table 56: Inreda Diabetic BV Pipeline Products & Ongoing Clinical Trials Overview 39

Table 57: Bi-Hormonal Artificial Pancreas-Product Status 39

Table 58: Bi-Hormonal Artificial Pancreas-Product Description 39

Table 59: Kencak LLC Pipeline Products & Ongoing Clinical Trials Overview 40

Table 60: BioArtificial Pancreas-Product Status 40

Table 61: BioArtificial Pancreas-Product Description 40

Table 62: Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 41

Table 63: Glucositter-Product Status 41

Table 64: Glucositter-Product Description 42

Table 65: MiniMed 640G System-Product Status 42

Table 66: MiniMed 640G System-Product Description 42

Table 67: Third-Generation Artificial Pancreas System-Product Status 43

Table 68: Third-Generation Artificial Pancreas System-Product Description 43

Table 69: Medtronic plc-Ongoing Clinical Trials Overview 44

Table 70: MiniMed 640G System-In-clinic Evaluation of the Predictive Low Glucose Management (PLGM) System in Adult and Pediatric Insulin Requiring Patients with Diabetes Using the Enlite 3 Sensor 45

Table 71: MiniMed 640G System-Prevention of Hypoglycaemia Using the Minimed 640G System 45

Table 72: MiniMed 640G System-Prevention of Hypoglycaemia with Predictive Insulin Suspend Using Medtronic Minimed 640G Sensor Augmented Insulin Pump in Children: The Sportguard Study 45

Table 73: Third-Generation Artificial Pancreas System-In-Clinic Feasibility Study to Observe the Overnight Closed Loop System 46

Table 74: Glucositter-Multicenter, Prospective, Open Label, Cross over, Pilot Trial to Evaluate Blood Glucose Control Overnight under Closed-loop Insulin Delivery with MD Logic Artificial Pancreas (MDLAP)System in Patients with Type 1 Diabetes 47

Table 75: Glucositter-Overnight Type 1 Diabetes Control Under MD-Logic Closed Loop System At The Patient's Home, Pilot Study 47

Table 76: Miromatrix Medical Inc. Pipeline Products & Ongoing Clinical Trials Overview 48

Table 77: Miro Pancreas-Product Status 48

Table 78: Miro Pancreas-Product Description 48

Table 79: Pacific Diabetes Technologies, Inc. Pipeline Products & Ongoing Clinical Trials Overview 49

Table 80: Single Indicating electrode Sensing Catheter-Product Status 49

Table 81: Single Indicating electrode Sensing Catheter-Product Description 49

Table 82: Pancreum, LLC Pipeline Products & Ongoing Clinical Trials Overview 50

Table 83: Genesis Artificial Pancreas-Product Status 50

Table 84: Genesis Artificial Pancreas-Product Description 50

Table 85: PharmaCyte Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 51

Table 86: Bio-Artificial Pancreas-Product Status 51

Table 87: Bio-Artificial Pancreas-Product Description 52

Table 88: Rensselaer Polytechnic Institute Pipeline Products & Ongoing Clinical Trials Overview 53

Table 89: Closed-Loop Artificial Pancreas System-Product Status 53

Table 90: Closed-Loop Artificial Pancreas System-Product Description 54

Table 91: Schneider Children's Medical Center of Israel Pipeline Products & Ongoing Clinical Trials Overview 55

Table 92: MD-Logic Artificial Pancreas-Product Status 55

Table 93: MD-Logic Artificial Pancreas-Product Description 56

Table 94: TecMed, Inc. Pipeline Products & Ongoing Clinical Trials Overview 57

Table 95: TecMed Artificial Pancreas-Product Status 57

Table 96: TecMed Artificial Pancreas-Product Description 57

Table 97: The University of Newcastle Pipeline Products & Ongoing Clinical Trials Overview 58

Table 98: Closed Glucose-Sensing Insulin-Delivery System-Product Status 58

Table 99: Closed Glucose-Sensing Insulin-Delivery System-Product Description 58

Table 100: Ultradian Diagnostics LLC Pipeline Products & Ongoing Clinical Trials Overview 59

Table 101: Artificial Pancreas-Product Status 59

Table 102: Artificial Pancreas-Product Description 59

Table 103: Universidad Autonoma de Madrid Pipeline Products & Ongoing Clinical Trials Overview 60

Table 104: Predictive Rule-Based Algorithm-Product Status 60

Table 105: Predictive Rule-Based Algorithm-Product Description 60

Table 106: Universitat Politecnica de Valencia Pipeline Products & Ongoing Clinical Trials Overview 61

Table 107: ClosedLoop 4Meal Control-Product Status 61

Table 108: ClosedLoop 4Meal Control-Product Description 61

Table 109: University of California, San Francisco Pipeline Products & Ongoing Clinical Trials Overview 62

Table 110: Bioartificial Pancreas-Product Status 62

Table 111: Bioartificial Pancreas-Product Description 62

Table 112: University of California, Santa Barbara Pipeline Products & Ongoing Clinical Trials Overview 63

Table 113: Closed-Loop Artificial Pancreas-Product Status 63

Table 114: Closed-Loop Artificial Pancreas-Product Description 63

Table 115: Pediatric Artificial Pancreas-Product Status 64

Table 116: Pediatric Artificial Pancreas-Product Description 64

Table 117: University of Cambridge Pipeline Products & Ongoing Clinical Trials Overview 65

Table 118: FlorenceD System-Product Status 65

Table 119: FlorenceD System-Product Description 65

Table 120: University of Florida Pipeline Products & Ongoing Clinical Trials Overview 66

Table 121: Bioartificial Pancreas-Type 1 Diabetes-Product Status 66

Table 122: Bioartificial Pancreas-Type 1 Diabetes-Product Description 66

Table 123: University of Virginia Pipeline Products & Ongoing Clinical Trials Overview 67

Table 124: DiAs-Product Status 67

Table 125: DiAs-Product Description 68

Table 126: University of Virginia-Ongoing Clinical Trials Overview 69

Table 127: DiAs-A Trial on Artificial Pancreas to Manage Type 1 diabetes By Automatically Regulating Insulin and Blood Sugar Levels 70

Table 128: ViaCyte, Inc. Pipeline Products & Ongoing Clinical Trials Overview 71

Table 129: VC-01 Combination Product-Product Status 71

Table 130: VC-01 Combination Product-Product Description 72

Table 131: ViaCyte, Inc.-Ongoing Clinical Trials Overview 73

Table 132: VC-01 Combination Product-A Prospective, Multicenter, Open-Label, First-in-Human Phase 1/2 Study with Two Cohorts to Evaluate the Safety, Tolerability, and Efficacy of Various Doses of VC-01 Combination Product in Subjects with Type 1 Diabetes Mellitus 74

Table 133: XERIS Pharmaceuticals, Inc. Pipeline Products & Ongoing Clinical Trials Overview 75

Table 134: G-Pump � BP-Product Status 75

Table 135: G-Pump � BP-Product Description 75

Table 136: Glossary 82

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Advanced Biosensors-Ohio, Llc

Animas Corporation

Beta-O2 Technologies Ltd.

Bigfoot Biomedical, Inc.

BioTex, Inc.

Boston University

Cerco Medical

Converge Biotech, Inc.

Covalor Medical, LLC

De Montfort University

Defymed

Diabeloop

Dose Safety Inc.

Imperial College London

Inreda Diabetic BV

Kencak LLC

Medtronic plc

Miromatrix Medical Inc.

Pacific Diabetes Technologies, Inc.

Pancreum, LLC

PharmaCyte Biotech, Inc.

Rensselaer Polytechnic Institute

Schneider Children's Medical Center of Israel

TecMed, Inc.

The University of Newcastle

Ultradian Diagnostics LLC

Universidad Autonoma de Madrid

Universitat Politecnica de Valencia

University of California, San Francisco

University of California, Santa Barbara

University of Cambridge

University of Florida

University of Virginia

ViaCyte, Inc.

XERIS Pharmaceuticals, Inc.

Advanced Biosensors-Ohio, Llc, Artificial Pancreas, Animas Corporation, Hypoglycemia-Hyperglycemia Minimizer System, Beta-O2 Technologies Ltd., �Air, Bigfoot Biomedical, Inc., Artificial Pancreas, BioTex, Inc., Artificial Pancreas, Boston University, Bionic Pancreas, Cerco Medical, Islet Sheet, Converge Biotech, Inc., Bioartificial Pancreas System, Covalor Medical, LLC, Artificial Pancreas, De Montfort University, InSmart Artificial Pancreas, Defymed, MAILPAN, Diabeloop, Diabeloop, Dose Safety Inc., Dose Safety Controller, Imperial College London, Bio-inspired Artificial Pancreas, Inreda Diabetic BV, Bi-Hormonal Artificial Pancreas, Kencak LLC, BioArtificial Pancreas, Medtronic plc, Glucositter, MiniMed 640G System, Third-Generation Artificial Pancreas System, Miromatrix Medical Inc., Miro Pancreas, Pacific Diabetes Technologies, Inc., Single Indicating electrode Sensing Catheter, Pancreum, LLC, Genesis Artificial Pancreas, PharmaCyte Biotech, Inc., Bio-Artificial Pancreas, Rensselaer Polytechnic Institute, Closed-Loop Artificial Pancreas System, Schneider Children's Medical Center of Israel, MD-Logic Artificial Pancreas, TecMed, Inc., TecMed Artificial Pancreas, The University of Newcastle, Closed Glucose-Sensing Insulin-Delivery System, Ultradian Diagnostics LLC, Artificial Pancreas, Universidad Autonoma de Madrid, Predictive Rule-Based Algorithm, Universitat Politecnica de Valencia, ClosedLoop 4Meal Control, University of California, San Francisco, Bioartificial Pancreas, University of California, Santa Barbara, Closed-Loop Artificial Pancreas, University of California, Santa Barbara, Pediatric Artificial Pancreas, University of Cambridge, FlorenceD System, University of Florida, Bioartificial Pancreas - Type 1 Diabetes, University of Virginia, DiAs, ViaCyte, Inc., VC-01 Combination Product, XERIS Pharmaceuticals, Inc., G-Pump - BP


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