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Blepharitis-Pipeline Review, H1 2015

Blepharitis-Pipeline Review, H1 2015


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Executive Summary

Blepharitis-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Blepharitis-Pipeline Review, H1 2015', provides an overview of the Blepharitis's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Blepharitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Blepharitis and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Blepharitis

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Blepharitis and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Blepharitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Blepharitis pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Blepharitis

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Blepharitis pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Blepharitis Overview 6

Therapeutics Development 7

Pipeline Products for Blepharitis-Overview 7

Pipeline Products for Blepharitis-Comparative Analysis 8

Blepharitis-Therapeutics under Development by Companies 9

Blepharitis-Pipeline Products Glance 10

Late Stage Products 10

Clinical Stage Products 11

Early Stage Products 12

Unknown Stage Products 13

Blepharitis-Products under Development by Companies 14

Blepharitis-Companies Involved in Therapeutics Development 15

Foamix Pharmaceuticals Ltd. 15

InSite Vision Incorporated 16

Laboratoires Thea S.A. 17

Novaliq GmbH 18

Blepharitis-Therapeutics Assessment 19

Assessment by Monotherapy Products 19

Assessment by Combination Products 20

Assessment by Target 21

Assessment by Mechanism of Action 23

Assessment by Route of Administration 25

Assessment by Molecule Type 27

Drug Profiles 28

(azithromycin + dexamethasone)-Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

azithromycin-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

dexamethasone-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

ISV-405-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

minocycline Gel-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

Nov-137-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Blepharitis-Recent Pipeline Updates 35

Blepharitis-Dormant Projects 37

Blepharitis-Product Development Milestones 38

Featured News & Press Releases 38

Jul 08, 2014: InSite Vision Plans to Submit New Drug Application to FDA for DexaSite for the Treatment of Blepharitis in Adults 38

Jul 23, 2013: InSite Vision Announces Top-line Results from the DOUBle Phase 3 Clinical Study for the Treatment of Moderate-to-Severe Blepharitis 39

Mar 25, 2013: InSite Vision Completes DOUBle Phase III Clinical Study Of AzaSite Plus And DexaSite For Treatment Of Blepharitis 39

Sep 07, 2012: InSite Vision Fully Enrolls Phase III DOUBle Clinical Study Of AzaSite Plus And DexaSite For Blepharitis 41

May 25, 2011: InSite Vision Receives SPA From FDA For DOUBle Phase III Clinical Trial Of AzaSite Plus And DexaSite 42

Apr 14, 2011: InSite Vision Updates Special Protocol Assessment Submission To FDA For Phase III Trial Of AzaSite Plus And DexaSite 43

Apr 26, 2010: Foamix is granted a fourth U.S. patent for OilGel, directed to pharmaceutical compositions and their dermatological, gynecological and ophthalmic applications 44

Appendix 45

Methodology 45

Coverage 45

Secondary Research 45

Primary Research 45

Expert Panel Validation 45

Contact Us 46

Disclaimer 46

List of Tables

Number of Products under Development for Blepharitis, H1 2015 7

Number of Products under Development for Blepharitis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Late Stage Development, H1 2015 10

Comparative Analysis by Clinical Stage Development, H1 2015 11

Comparative Analysis by Early Stage Development, H1 2015 12

Comparative Analysis by Unknown Stage Development, H1 2015 13

Products under Development by Companies, H1 2015 14

Blepharitis-Pipeline by Foamix Pharmaceuticals Ltd., H1 2015 15

Blepharitis-Pipeline by InSite Vision Incorporated, H1 2015 16

Blepharitis-Pipeline by Laboratoires Thea S.A., H1 2015 17

Blepharitis-Pipeline by Novaliq GmbH, H1 2015 18

Assessment by Monotherapy Products, H1 2015 19

Assessment by Combination Products, H1 2015 20

Number of Products by Stage and Target, H1 2015 22

Number of Products by Stage and Mechanism of Action, H1 2015 24

Number of Products by Stage and Route of Administration, H1 2015 26

Number of Products by Stage and Molecule Type, H1 2015 27

Blepharitis Therapeutics-Recent Pipeline Updates, H1 2015 35

Blepharitis-Dormant Projects, H1 2015 37

List of Figures

Number of Products under Development for Blepharitis, H1 2015 7

Number of Products under Development for Blepharitis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Assessment by Monotherapy Products, H1 2015 19

Number of Products by Top 10 Targets, H1 2015 21

Number of Products by Stage and Top 10 Targets, H1 2015 22

Number of Products by Top 10 Mechanism of Actions, H1 2015 23

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 24

Number of Products by Top 10 Routes of Administration, H1 2015 25

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 26

Number of Products by Stage and Top 10 Molecule Types, H1 2015 27

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Foamix Pharmaceuticals Ltd.

InSite Vision Incorporated

Laboratoires Thea S.A.

Novaliq GmbH

Blepharitis Therapeutic Products under Development, Key Players in Blepharitis Therapeutics, Blepharitis Pipeline Overview, Blepharitis Pipeline, Blepharitis Pipeline Assessment


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