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Brain Ischemia-Pipeline Review, H1 2015

Brain Ischemia-Pipeline Review, H1 2015


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Executive Summary

Brain Ischemia-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Brain Ischemia-Pipeline Review, H1 2015', provides an overview of the Brain Ischemia's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Brain Ischemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Brain Ischemia and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Brain Ischemia

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Brain Ischemia and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Brain Ischemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Brain Ischemia pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Brain Ischemia

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Brain Ischemia pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 6

Introduction 7

Global Markets Direct Report Coverage 7

Brain Ischemia Overview 8

Therapeutics Development 9

Pipeline Products for Brain Ischemia-Overview 9

Pipeline Products for Brain Ischemia-Comparative Analysis 10

Brain Ischemia-Therapeutics under Development by Companies 11

Brain Ischemia-Therapeutics under Investigation by Universities/Institutes 12

Brain Ischemia-Pipeline Products Glance 13

Late Stage Products 13

Clinical Stage Products 14

Early Stage Products 15

Brain Ischemia-Products under Development by Companies 16

Brain Ischemia-Products under Investigation by Universities/Institutes 17

Brain Ischemia-Companies Involved in Therapeutics Development 18

Edge Therapeutics, Inc. 18

Immune Pharmaceuticals, Ltd. 19

Lixte Biotechnology Holdings, Inc. 20

NeuroNascent, Inc. 21

NeurOp, Inc 22

Prolong Pharmaceuticals 23

Sylentis S.A. 24

The International Biotechnology Center (IBC) Generium 25

Vect-Horus S.A.S 26

Brain Ischemia-Therapeutics Assessment 27

Assessment by Monotherapy Products 27

Assessment by Target 28

Assessment by Mechanism of Action 30

Assessment by Route of Administration 32

Assessment by Molecule Type 34

Drug Profiles 36

AB-002-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

CIGB-845-Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

EG-1962-Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

F-573-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

GNR-014-Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

Humanin-Drug Profile 42

Product Description 42

Mechanism of Action 42

R&D Progress 42

LAU-0901-Drug Profile 43

Product Description 43

Mechanism of Action 43

R&D Progress 43

LB-100-Drug Profile 44

Product Description 44

Mechanism of Action 44

R&D Progress 44

LB-102-Drug Profile 46

Product Description 46

Mechanism of Action 46

R&D Progress 46

NA-1-Drug Profile 47

Product Description 47

Mechanism of Action 47

R&D Progress 47

NP-10679-Drug Profile 48

Product Description 48

Mechanism of Action 48

R&D Progress 48

RNAi Oligonucleotide for Cerebral Ischemia and Dementia-Drug Profile 49

Product Description 49

Mechanism of Action 49

R&D Progress 49

Sanguinate-Drug Profile 50

Product Description 50

Mechanism of Action 50

R&D Progress 50

Small Molecules for Brain Ischemia-Drug Profile 52

Product Description 52

Mechanism of Action 52

R&D Progress 52

Small Molecules for Brain Ischemia-Drug Profile 53

Product Description 53

Mechanism of Action 53

R&D Progress 53

Small Molecules for Brain Ischemia and Ischemic Stroke-Drug Profile 54

Product Description 54

Mechanism of Action 54

R&D Progress 54

Small Molecules to Activate Sigma Receptor for CNS Disorders-Drug Profile 55

Product Description 55

Mechanism of Action 55

R&D Progress 55

Small Molecules to Antagonize Gpr17 for Brain Ischemia-Drug Profile 56

Product Description 56

Mechanism of Action 56

R&D Progress 56

Stem Cell Therapy for Ischemia-Drug Profile 57

Product Description 57

Mechanism of Action 57

R&D Progress 57

Synthetic Peptide for Central Nervous System Disorders-Drug Profile 58

Product Description 58

Mechanism of Action 58

R&D Progress 58

VHN-439-Drug Profile 59

Product Description 59

Mechanism of Action 59

R&D Progress 59

Brain Ischemia-Recent Pipeline Updates 60

Brain Ischemia-Dormant Projects 64

Brain Ischemia-Discontinued Products 65

Appendix 66

Methodology 66

Coverage 66

Secondary Research 66

Primary Research 66

Expert Panel Validation 66

Contact Us 66

Disclaimer 67

List of Tables

Number of Products under Development for Brain Ischemia, H1 2015 9

Number of Products under Development for Brain Ischemia-Comparative Analysis, H1 2015 10

Number of Products under Development by Companies, H1 2015 11

Number of Products under Investigation by Universities/Institutes, H1 2015 12

Comparative Analysis by Late Stage Development, H1 2015 13

Comparative Analysis by Clinical Stage Development, H1 2015 14

Comparative Analysis by Early Stage Development, H1 2015 15

Products under Development by Companies, H1 2015 16

Products under Investigation by Universities/Institutes, H1 2015 17

Brain Ischemia-Pipeline by Edge Therapeutics, Inc., H1 2015 18

Brain Ischemia-Pipeline by Immune Pharmaceuticals, Ltd., H1 2015 19

Brain Ischemia-Pipeline by Lixte Biotechnology Holdings, Inc., H1 2015 20

Brain Ischemia-Pipeline by NeuroNascent, Inc., H1 2015 21

Brain Ischemia-Pipeline by NeurOp, Inc, H1 2015 22

Brain Ischemia-Pipeline by Prolong Pharmaceuticals, H1 2015 23

Brain Ischemia-Pipeline by Sylentis S.A., H1 2015 24

Brain Ischemia-Pipeline by The International Biotechnology Center (IBC) Generium, H1 2015 25

Brain Ischemia-Pipeline by Vect-Horus S.A.S , H1 2015 26

Assessment by Monotherapy Products, H1 2015 27

Number of Products by Stage and Target, H1 2015 29

Number of Products by Stage and Mechanism of Action, H1 2015 31

Number of Products by Stage and Route of Administration, H1 2015 33

Number of Products by Stage and Molecule Type, H1 2015 35

Brain Ischemia Therapeutics-Recent Pipeline Updates, H1 2015 60

Brain Ischemia-Dormant Projects, H1 2015 64

Brain Ischemia-Discontinued Products, H1 2015 65

List of Figures

Number of Products under Development for Brain Ischemia, H1 2015 9

Number of Products under Development for Brain Ischemia-Comparative Analysis, H1 2015 10

Number of Products under Development by Companies, H1 2015 11

Number of Products under Investigation by Universities/Institutes, H1 2015 12

Comparative Analysis by Clinical Stage Development, H1 2015 14

Comparative Analysis by Early Stage Products, H1 2015 15

Assessment by Monotherapy Products, H1 2015 27

Number of Products by Top 10 Targets, H1 2015 28

Number of Products by Stage and Top 10 Targets, H1 2015 29

Number of Products by Top 10 Mechanism of Actions, H1 2015 30

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 31

Number of Products by Top 10 Routes of Administration, H1 2015 32

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 33

Number of Products by Top 10 Molecule Types, H1 2015 34

Number of Products by Stage and Top 10 Molecule Types, H1 2015 35

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Edge Therapeutics, Inc.

Immune Pharmaceuticals, Ltd.

Lixte Biotechnology Holdings, Inc.

NeuroNascent, Inc.

NeurOp, Inc

Prolong Pharmaceuticals

Sylentis S.A.

The International Biotechnology Center (IBC) Generium

Vect-Horus S.A.S

Brain Ischemia Therapeutic Products under Development, Key Players in Brain Ischemia Therapeutics, Brain Ischemia Pipeline Overview, Brain Ischemia Pipeline, Brain Ischemia Pipeline Assessment


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