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Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2016

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2016


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Executive Summary

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2016

Summary

Global Markets Direct's, 'Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Review, H2 2016', provides in depth analysis on Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted pipeline therapeutics.

The report provides comprehensive information on the Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics development and features dormant and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note:

*Certain sections in the report may be removed or altered based on the availability and relevance of data.

*Updated report will be delivered in 48 hours of order confirmation.

Scope

The report provides a snapshot of the global therapeutic landscape for Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)

The report reviews Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics and enlists all their major and minor projects

The report assesses Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

The report summarizes all the dormant and discontinued pipeline projects

The report reviews latest news and deals related to Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) targeted therapeutics

Reasons To Buy

Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand the targeted therapy areas and indications for Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)

Identify the use of drugs for target identification and drug repurposing

Identify potential new clients or partners in the target demographic

Develop strategic initiatives by understanding the focus areas of leading companies

Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics

Devise corrective measures for pipeline projects by understanding Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) development landscape

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Overview 6

Therapeutics Development 7

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Products under Development by Stage of Development 7

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Products under Development by Therapy Area 8

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Products under Development by Indication 9

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Pipeline Products Glance 10

Early Stage Products 10

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Products under Development by Companies 11

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Products under Development by Universities/Institutes 13

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Therapeutics Assessment 15

Assessment by Monotherapy/Combination Products 15

Assessment by Mechanism of Action 16

Assessment by Route of Administration 17

Assessment by Molecule Type 18

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Companies Involved in Therapeutics Development 20

ALSP, Inc. 20

BioMAS Ltd. 21

Oncomatryx Biopharma, S.L. 22

Phelix Therapeutics, LLC 23

Virobay Inc. 24

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Drug Profiles 25

ALP-496-Drug Profile 25

Product Description 25

Mechanism Of Action 25

R&D Progress 25

CIBP-4-Drug Profile 27

Product Description 27

Mechanism Of Action 27

R&D Progress 27

Drugs to Inhibit Cathepsin B for Ebola Viral Infections-Drug Profile 28

Product Description 28

Mechanism Of Action 28

R&D Progress 28

OMTX-001-Drug Profile 29

Product Description 29

Mechanism Of Action 29

R&D Progress 29

SAS-Drug Profile 30

Product Description 30

Mechanism Of Action 30

R&D Progress 30

Small Molecule to Inhibit Cathepsin B for Oncology-Drug Profile 31

Product Description 31

Mechanism Of Action 31

R&D Progress 31

Small Molecules to Inhibit Cathepsin B for Alzheimer's Disease-Drug Profile 32

Product Description 32

Mechanism Of Action 32

R&D Progress 32

VBY-129-Drug Profile 33

Product Description 33

Mechanism Of Action 33

R&D Progress 33

VBY-285-Drug Profile 34

Product Description 34

Mechanism Of Action 34

R&D Progress 34

VBY-376-Drug Profile 35

Product Description 35

Mechanism Of Action 35

R&D Progress 35

VBY-825-Drug Profile 36

Product Description 36

Mechanism Of Action 36

R&D Progress 36

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Dormant Projects 37

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1)-Featured News & Press Releases 38

Apr 19, 2016: American Life Science Pharmaceuticals Obtains Patent 38

Jan 25, 2016: ALSP invited to Give Oral Presentation at the Keystone TBI Conference January 25-27 in Santa Fe, New Mexico 38

Nov 14, 2011: Virobay's Spectrum-Selective Cathepsin Inhibitor Shows Efficacy In Bone Cancer Model 38

Appendix 40

Methodology 40

Coverage 40

Secondary Research 40

Primary Research 40

Expert Panel Validation 40

Contact Us 40

Disclaimer 41

List of Figures

Number of Products under Development for, H2 2016 7

Number of Products under Development by Therapy Area, H2 2016 8

Number of Products under Development by Top 10 Indication, H2 2016 9

Comparative Analysis by Early Stage Products, H2 2016 10

Assessment by Monotherapy/Combination Products, H2 2016 15

Number of Products by Stage and Mechanism of Actions, H2 2016 16

Number of Products by Stage and Routes of Administration, H2 2016 17

Number of Products by Molecule Types, H2 2016 18

Number of Products by Stage and Molecule Type, H2 2016 18

List of Tables

Number of Products under Development for, H2 2016 7

Number of Products under Development by Therapy Area, H2 2016 8

Number of Products under Development by Indication, H2 2016 9

Comparative Analysis by Early Stage Products, H2 2016 10

Number of Products under Development by Companies, H2 2016 11

Products under Development by Companies, H2 2016 12

Number of Products under Investigation by Universities/Institutes, H2 2016 13

Products under Investigation by Universities/Institutes, H2 2016 14

Assessment by Monotherapy/Combination Products, H2 2016 15

Number of Products by Stage and Mechanism of Action, H2 2016 16

Number of Products by Stage and Route of Administration, H2 2016 17

Number of Products by Stage and Molecule Type, H2 2016 19

Pipeline by ALSP, Inc., H2 2016 20

Pipeline by BioMAS Ltd., H2 2016 21

Pipeline by Oncomatryx Biopharma, S.L., H2 2016 22

Pipeline by Phelix Therapeutics, LLC, H2 2016 23

Pipeline by Virobay Inc., H2 2016 24

Dormant Projects, H2 2016 37

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ALSP, Inc., BioMAS Ltd., Oncomatryx Biopharma, S.L., Phelix Therapeutics, LLC, Virobay Inc.

Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Therapeutic Products under Development, Key Players in Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Therapeutics, Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Pipeline Overview, Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Pipeline, Cathepsin B (APP Secretase or Cathepsin B1 or CTSB or EC 3.4.22.1) Pipeline Assessment


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