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Cholera-Pipeline Review, H1 2015

Cholera-Pipeline Review, H1 2015

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Executive Summary

Cholera-Pipeline Review, H1 2015


Global Markets Direct's, 'Cholera-Pipeline Review, H1 2015', provides an overview of the Cholera's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Cholera, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Cholera and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.


The report provides a snapshot of the global therapeutic landscape of Cholera

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Cholera and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Cholera products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Cholera pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Cholera

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Cholera pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Cholera Overview 6

Therapeutics Development 7

Pipeline Products for Cholera-Overview 7

Pipeline Products for Cholera-Comparative Analysis 8

Cholera-Therapeutics under Development by Companies 9

Cholera-Therapeutics under Investigation by Universities/Institutes 10

Cholera-Pipeline Products Glance 11

Late Stage Products 11

Clinical Stage Products 12

Early Stage Products 13

Cholera-Products under Development by Companies 14

Cholera-Products under Investigation by Universities/Institutes 15

Cholera-Companies Involved in Therapeutics Development 16

Beijing Minhai Biotechnology Co., Ltd 16

Napo Pharmaceuticals, Inc. 17

PaxVax 18

Cholera-Therapeutics Assessment 19

Assessment by Monotherapy Products 19

Assessment by Target 20

Assessment by Mechanism of Action 21

Assessment by Route of Administration 22

Assessment by Molecule Type 23

Drug Profiles 25

AKT-10082-Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

cholera (trivalent) vaccine-Drug Profile 26

Product Description 26

Mechanism of Action 26

R&D Progress 26

crofelemer DR-Drug Profile 27

Product Description 27

Mechanism of Action 27

R&D Progress 27

Peptide for Cholera and Guillain-Barre Syndrome-Drug Profile 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

PXVX-0200-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

Cholera-Recent Pipeline Updates 31

Cholera-Dormant Projects 35

Cholera-Discontinued Products 36

Cholera-Product Development Milestones 37

Featured News & Press Releases 37

Dec 08, 2014: PaxVax Announces Primary Endpoints Met in Phase 3 Cholera Vaccine Trial 37

Sep 30, 2014: Specialty Vaccine Company PaxVax to Present at 13th Annual BIO Investor Forum 37

Jul 01, 2014: Specialty Vaccine Company PaxVax Announces Positive Efficacy Results for Phase 3 Cholera Challenge Study 38

May 27, 2014: Specialty Vaccine Company PaxVax to Present at the Jefferies 2014 Global Healthcare Conference 39

Jan 09, 2014: PaxVax Announces Positive Interim Results for Phase 3 Cholera Challenge Study; Clinical Trial Program to Proceed as Planned 39

Sep 06, 2013: PaxVax Initiates Phase 3 Clinical Trial Challenge Studies for Single-Dose Oral Cholera Vaccine 41

Nov 14, 2012: PaxVax Presents Phase I Clinical Trial Results Of Single-dose Cholera Vaccine At 2012 ASTMH Annual Meeting 42

Mar 19, 2012: FDA Accepts PaxVax's IND For Single-Dose Oral Cholera Vaccine 42

Appendix 44

Methodology 44

Coverage 44

Secondary Research 44

Primary Research 44

Expert Panel Validation 44

Contact Us 44

Disclaimer 45

List of Tables

Number of Products under Development for Cholera, H1 2015 7

Number of Products under Development for Cholera-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Number of Products under Investigation by Universities/Institutes, H1 2015 10

Comparative Analysis by Late Stage Development, H1 2015 11

Comparative Analysis by Clinical Stage Development, H1 2015 12

Comparative Analysis by Early Stage Development, H1 2015 13

Products under Development by Companies, H1 2015 14

Products under Investigation by Universities/Institutes, H1 2015 15

Cholera-Pipeline by Beijing Minhai Biotechnology Co., Ltd, H1 2015 16

Cholera-Pipeline by Napo Pharmaceuticals, Inc., H1 2015 17

Cholera-Pipeline by PaxVax, H1 2015 18

Assessment by Monotherapy Products, H1 2015 19

Number of Products by Stage and Target, H1 2015 20

Number of Products by Stage and Mechanism of Action, H1 2015 21

Number of Products by Stage and Route of Administration, H1 2015 22

Number of Products by Stage and Molecule Type, H1 2015 24

Cholera Therapeutics-Recent Pipeline Updates, H1 2015 31

Cholera-Dormant Projects, H1 2015 35

Cholera-Discontinued Products, H1 2015 36

List of Figures

Number of Products under Development for Cholera, H1 2015 7

Number of Products under Development for Cholera-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Early Stage Products, H1 2015 13

Assessment by Monotherapy Products, H1 2015 19

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 22

Number of Products by Top 10 Molecule Types, H1 2015 23

Number of Products by Stage and Top 10 Molecule Types, H1 2015 24

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Cholera Therapeutic Products under Development, Key Players in Cholera Therapeutics, Cholera Pipeline Overview, Cholera Pipeline, Cholera Pipeline Assessment

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