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Gastroenteritis-Pipeline Review, H1 2015

Gastroenteritis-Pipeline Review, H1 2015


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Executive Summary

Gastroenteritis-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Gastroenteritis-Pipeline Review, H1 2015', provides an overview of the Gastroenteritis's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Gastroenteritis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Gastroenteritis and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Gastroenteritis

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Gastroenteritis and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Gastroenteritis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Gastroenteritis pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Gastroenteritis

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Gastroenteritis pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Gastroenteritis Overview 6

Therapeutics Development 7

Pipeline Products for Gastroenteritis-Overview 7

Pipeline Products for Gastroenteritis-Comparative Analysis 8

Gastroenteritis-Therapeutics under Development by Companies 9

Gastroenteritis-Therapeutics under Investigation by Universities/Institutes 10

Gastroenteritis-Pipeline Products Glance 11

Late Stage Products 11

Clinical Stage Products 12

Early Stage Products 13

Gastroenteritis-Products under Development by Companies 14

Gastroenteritis-Products under Investigation by Universities/Institutes 15

Gastroenteritis-Companies Involved in Therapeutics Development 16

Cocrystal Pharma, Inc. 16

RedHill Biopharma Ltd. 17

Takeda Pharmaceutical Company Limited 18

UMN Pharma Inc. 19

Gastroenteritis-Therapeutics Assessment 20

Assessment by Monotherapy Products 20

Assessment by Target 21

Assessment by Mechanism of Action 23

Assessment by Route of Administration 25

Assessment by Molecule Type 27

Drug Profiles 29

Antibodies for Gastroenteritis-Drug Profile 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

Antibody to Target TRIM-21 for Gastrointestinal and Ear Nose Throat Disorders-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

ondansetron hydrochloride CR-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

Small Molecules to Inhibit RNA Dependent RNA Polymerase for Acute Gastroenteritis-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

TAK-214-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

UMN-2002-Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

UMN-2003-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

Gastroenteritis-Recent Pipeline Updates 37

Gastroenteritis-Product Development Milestones 42

Featured News & Press Releases 42

Mar 02, 2015: Positive Bioavailability Studies of RedHill's BEKINDA to be Presented at the 2015 American Society for Clinical Pharmacology and Therapeutics Meeting 42

Dec 17, 2014: RedHill Biopharma Announces First Patients Enrolled in the Phase III Study of RHB-102 (BEKINDA) for Gastroenteritis and Gastritis 42

Dec 09, 2014: RedHill Biopharma Submits BEKINDA (RHB-102) European Marketing Authorization Application for Oncology Support 43

Sep 03, 2014: RedHill Biopharma Initiates Phase III Study of RHB-102 for Gastroenteritis 44

Dec 08, 2011: The New England Journal Of Medicine Publishes Study Showing LigoCyte's Norovirus Vaccine Demonstrates Protection Against Illness 45

Oct 25, 2010: LigoCyte Presents Positive Results From Norovirus Vaccine Challenge Study At IDSA Annual Meeting 47

Appendix 49

Methodology 49

Coverage 49

Secondary Research 49

Primary Research 49

Expert Panel Validation 49

Contact Us 49

Disclaimer 50

List of Tables

Number of Products under Development for Gastroenteritis, H1 2015 7

Number of Products under Development for Gastroenteritis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Number of Products under Investigation by Universities/Institutes, H1 2015 10

Comparative Analysis by Late Stage Development, H1 2015 11

Comparative Analysis by Clinical Stage Development, H1 2015 12

Comparative Analysis by Early Stage Development, H1 2015 13

Products under Development by Companies, H1 2015 14

Products under Investigation by Universities/Institutes, H1 2015 15

Gastroenteritis-Pipeline by Cocrystal Pharma, Inc., H1 2015 16

Gastroenteritis-Pipeline by RedHill Biopharma Ltd., H1 2015 17

Gastroenteritis-Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 18

Gastroenteritis-Pipeline by UMN Pharma Inc., H1 2015 19

Assessment by Monotherapy Products, H1 2015 20

Number of Products by Stage and Target, H1 2015 22

Number of Products by Stage and Mechanism of Action, H1 2015 24

Number of Products by Stage and Route of Administration, H1 2015 26

Number of Products by Stage and Molecule Type, H1 2015 28

Gastroenteritis Therapeutics-Recent Pipeline Updates, H1 2015 37

List of Figures

Number of Products under Development for Gastroenteritis, H1 2015 7

Number of Products under Development for Gastroenteritis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Number of Products under Investigation by Universities/Institutes, H1 2015 10

Comparative Analysis by Early Stage Products, H1 2015 13

Assessment by Monotherapy Products, H1 2015 20

Number of Products by Top 10 Targets, H1 2015 21

Number of Products by Stage and Top 10 Targets, H1 2015 22

Number of Products by Top 10 Mechanism of Actions, H1 2015 23

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 24

Number of Products by Top 10 Routes of Administration, H1 2015 25

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 26

Number of Products by Top 10 Molecule Types, H1 2015 27

Number of Products by Stage and Top 10 Molecule Types, H1 2015 28

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Cocrystal Pharma, Inc.

RedHill Biopharma Ltd.

Takeda Pharmaceutical Company Limited

UMN Pharma Inc.

Gastroenteritis Therapeutic Products under Development, Key Players in Gastroenteritis Therapeutics, Gastroenteritis Pipeline Overview, Gastroenteritis Pipeline, Gastroenteritis Pipeline Assessment


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