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Gastrointestinal Radiation Toxicity-Pipeline Review, H1 2015

Gastrointestinal Radiation Toxicity-Pipeline Review, H1 2015


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Executive Summary

Gastrointestinal Radiation Toxicity-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Gastrointestinal Radiation Toxicity-Pipeline Review, H1 2015', provides an overview of the Gastrointestinal Radiation Toxicity's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Gastrointestinal Radiation Toxicity, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Gastrointestinal Radiation Toxicity and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Gastrointestinal Radiation Toxicity

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Gastrointestinal Radiation Toxicity and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Gastrointestinal Radiation Toxicity products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Gastrointestinal Radiation Toxicity pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Gastrointestinal Radiation Toxicity

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Gastrointestinal Radiation Toxicity pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Gastrointestinal Radiation Toxicity Overview 6

Therapeutics Development 7

Pipeline Products for Gastrointestinal Radiation Toxicity-Overview 7

Pipeline Products for Gastrointestinal Radiation Toxicity-Comparative Analysis 8

Gastrointestinal Radiation Toxicity-Therapeutics under Development by Companies 9

Gastrointestinal Radiation Toxicity-Pipeline Products Glance 10

Clinical Stage Products 10

Early Stage Products 11

Gastrointestinal Radiation Toxicity-Products under Development by Companies 12

Gastrointestinal Radiation Toxicity-Companies Involved in Therapeutics Development 13

Aeolus Pharmaceuticals, Inc. 13

Avaxia Biologics, Inc. 14

Soligenix, Inc. 15

Gastrointestinal Radiation Toxicity-Therapeutics Assessment 16

Assessment by Monotherapy Products 16

Assessment by Target 17

Assessment by Mechanism of Action 19

Assessment by Route of Administration 21

Assessment by Molecule Type 23

Drug Profiles 25

2A2-Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

AEOL-10150-Drug Profile 27

Product Description 27

Mechanism of Action 27

R&D Progress 27

AVX-470-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

m2A2-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

SGX-202-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

Gastrointestinal Radiation Toxicity-Recent Pipeline Updates 33

Gastrointestinal Radiation Toxicity-Dormant Projects 41

Gastrointestinal Radiation Toxicity-Product Development Milestones 42

Featured News & Press Releases 42

Aug 01, 2014: Soligenix Receives Additional NIAID Funding to Advance Development of OrbeShield in GI ARS 42

Sep 19, 2013: Soligenix Awarded BARDA Contract Valued up to $26.3 Million for Advanced Development of OrbeShield in GI ARS 42

Feb 20, 2013: Soligenix Submits BARDA Contract Proposal For Development Of OrbeShield In Gastrointestinal Acute Radiation Syndrome 43

Jan 29, 2013: Soligenix's OrbeShield Receives FDA Fast Track Designation For Reduction Of Mortality Associated With Gastrointestinal Acute Radiation Syndrome 44

Jan 07, 2013: BARDA Invites Soligenix To Submit Contract Proposal For Development Of OrbeShield In GI ARS 45

Appendix 46

Methodology 46

Coverage 46

Secondary Research 46

Primary Research 46

Expert Panel Validation 46

Contact Us 46

Disclaimer 47

List of Tables

Number of Products under Development for Gastrointestinal Radiation Toxicity, H1 2015 7

Number of Products under Development for Gastrointestinal Radiation Toxicity-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Comparative Analysis by Early Stage Development, H1 2015 11

Products under Development by Companies, H1 2015 12

Gastrointestinal Radiation Toxicity-Pipeline by Aeolus Pharmaceuticals, Inc., H1 2015 13

Gastrointestinal Radiation Toxicity-Pipeline by Avaxia Biologics, Inc., H1 2015 14

Gastrointestinal Radiation Toxicity-Pipeline by Soligenix, Inc., H1 2015 15

Assessment by Monotherapy Products, H1 2015 16

Number of Products by Stage and Target, H1 2015 18

Number of Products by Stage and Mechanism of Action, H1 2015 20

Number of Products by Stage and Route of Administration, H1 2015 22

Number of Products by Stage and Molecule Type, H1 2015 24

Gastrointestinal Radiation Toxicity Therapeutics-Recent Pipeline Updates, H1 2015 33

Gastrointestinal Radiation Toxicity-Dormant Projects, H1 2015 41

List of Figures

Number of Products under Development for Gastrointestinal Radiation Toxicity, H1 2015 7

Number of Products under Development for Gastrointestinal Radiation Toxicity-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Early Stage Products, H1 2015 11

Assessment by Monotherapy Products, H1 2015 16

Number of Products by Top 10 Targets, H1 2015 17

Number of Products by Stage and Top 10 Targets, H1 2015 18

Number of Products by Top 10 Mechanism of Actions, H1 2015 19

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 20

Number of Products by Top 10 Routes of Administration, H1 2015 21

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 22

Number of Products by Top 10 Molecule Types, H1 2015 23

Number of Products by Stage and Top 10 Molecule Types, H1 2015 24

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Aeolus Pharmaceuticals, Inc.

Avaxia Biologics, Inc.

Soligenix, Inc.

Gastrointestinal Radiation Toxicity Therapeutic Products under Development, Key Players in Gastrointestinal Radiation Toxicity Therapeutics, Gastrointestinal Radiation Toxicity Pipeline Overview, Gastrointestinal Radiation Toxicity Pipeline, Gastrointestinal Radiation Toxicity Pipeline Assessment


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