Ionis Pharmaceuticals Inc (IONS) - Pharmaceuticals & Healthcare - Deals and Alliances Profile
October 2018
94
About the Report
About the Report
Summary
Ionis Pharmaceuticals Inc (Ionis) formerly ISIS Pharmaceuticals, Inc. focuses on the discovery and development of RNA-targeted drugs. The company develops first in-class medicines for the treatment of cardiovascular and metabolic disorders, cancer and rare diseases. Ionis develops its products based on its proprietary antisense technology. Its lead product candidates in Phase III development include Kynamro injection being developed in collaboration with Genzyme for the reduction of low-density lipoprotein cholesterol in patients suffering from homozygous familial hypercholesterolemia, or HoFH; Volanesorsen being developed for the treatment of rare, genetic disorders marked by severely high triglyceride levels; IONIS-TTRRx, a first-in-class drug for the treatment of all forms of TTR amyloidosis and Nusinersen being developed for the spinal muscular atrophy (SMA). Ionis is headquartered in Carlsbad, California, the US.
Ionis Pharmaceuticals Inc (IONS)-Pharmaceuticals & Healthcare-Deals and Alliances Profile provides you comprehensive data and trend analysis of the company's Mergers and Acquisitions (M&As), partnerships and financings. The report provides detailed information on Mergers and Acquisitions, Equity/Debt Offerings, Private Equity, Venture Financing and Partnership transactions recorded by the company over a five year period. The report offers detailed comparative data on the number of deals and their value categorized into deal types, sub-sector and regions.
GlobalData derived the data presented in this report from proprietary in-house Pharma eTrack deals database, and primary and secondary research.
Scope
- Financial Deals-Analysis of the company's financial deals including Mergers and Acquisitions, Equity/Debt Offerings, Private Equity, Venture Financing and Partnerships.
- Deals by Year-Chart and table displaying information encompassing the number of deals and value reported by the company by year, for a five year period.
- Deals by Type-Chart and table depicting information including the number of deals and value reported by the company by type such as Mergers and Acquisitions, Equity/Debt Offering etc.
- Deals by Region-Chart and table presenting information on the number of deals and value reported by the company by region, which includes North America, Europe, Asia Pacific, the Middle East and Africa and South and Central America.
- Deals by Sub-sector-Chart and table showing information on the number of deals and value reported by the company, by sub-sector.
- Major Deals-Information on the company's major financial deals. Each such deal has a brief summary, deal type, deal rationale; and deal financials and target Company's (major public companies) key financial metrics and ratios.
- Business Description-A brief description of the company's operations.
- Key Employees-A list of the key executives of the company.
- Important Locations and Subsidiaries-A list and contact details of key centers of operation and subsidiaries of the company.
- Key Competitors-A list of the key competitors of the company.
- Key Recent Developments-A brief on recent news about the company.
Reasons to Buy
Get detailed information on the company's financial deals that enable you to understand the company's expansion/divestiture and fund requirements
- The profile enables you to analyze the company's financial deals by region, by year, by business segments and by type, for a five year period.
Understand the company's business segments' expansion / divestiture strategy
- The profile presents deals from the company's core business segments' perspective to help you understand its corporate strategy.
Access elaborate information on the company's recent financial deals that enable you to understand the key deals which have shaped the company
- Detailed information on major recent deals includes a summary of each deal, deal type, deal rationale, deal financials and Target Company's key financial metrics and ratios.
Equip yourself with detailed information about the company's operations to identify potential customers and suppliers.
- The profile analyzes the company's business structure, locations and subsidiaries, key executives and key competitors.
Stay up-to-date on the major developments affecting the company
- Recent developments concerning the company presented in the profile help you track important events.
Gain key insights into the company for academic or business research
- Key elements such as break up of deals into categories and information on detailed major deals are incorporated into the profile to assist your academic or business research needs.
Note*: Some sections may be missing if data is unavailable for the company.
Products
Products
Ionis Pharmaceuticals Inc, Deal Analysis, Mergers, Acquisitions, Asset Purchases, Asset Divestitures, Company Divestitures, Equity Offerings, Capital Raising, Debt Offerings, IPOs, Initial Public Offering, Private Placement, Private Investment In Public Equities, Secondary Offerings, Follow-On Offerings, Debt Private Placement, Public Debt Placement, Partnerships, Joint Venture, Licensing Agreements, Co-Marketing Agreements, Upfront Payment, Milestone Payment, Phases, Clinical Trials, Private Equity, Venture Capital, PE,VC, Asset Finance, Project Finance, Tax Equity Financing, Bond Financing, Lease Financing, New Build Financing, Deal Analysis By Market/sector, Deal Analysis By Geography, Deal Analysis By Deal Types, Key Employees, Locations And Subsidiaries, Competitors, Recent News, Company Overview, Key Facts, Deals By Year, Deal Details, Recent Developments, Significant Developments.
Table of Contents
Table of Contents
Table of Contents
Table of Contents 3
List of Tables 5
List of Figures 6
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 7
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 8
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 9
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 10
Ionis Pharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 12
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 13
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deal Details 16
Private Equity 16
Ionis Pharma Recommends Stockholders to Reject Mini-Tender Offer of TRC Capital 16
Partnerships 17
Ionis Pharma Enters into Collaboration Agreement with Roche 17
Cerveau Technologies Enters into Research Agreement with Ionis Pharma 18
SRI International Enters into Reaserch Agreement with Ionis Pharma 19
Biogen and Ionis Pharma Enter into Agreement 20
Biogen and Ionis Pharma Enter into Agreement 21
Novartis Enters into Option Agreement with Ionis Pharma and Akcea Therapeutics 22
Ionis Pharma Enters into Agreement with Dynacure 24
Ionis Pharma Enters into Agreement with Cystic Fibrosis Foundation 25
Ionis Pharma Partners with University of Texas MD Anderson Cancer Center 26
Biogazelle Enters into Research Agreement with Isis Pharma 27
Isis Pharma Enters into Agreement with Janssen Biotech to Discover and Develop RNA-Targeted Therapeutics 28
Biogen Idec And Isis Pharma Enter Into R&D Agreement To Develop Treatments For Neurological Disorders 29
Roche Enters Into Co-Development Agreement With Isis Pharma For Huntington's Disease Treatment 30
AstraZeneca Expands Co-Development Agreement with Isis Pharma 31
Biogen Idec Enters Into Agreement With Isis Pharma To Develop Antisense Drugs For Neurological Disorders 32
Biogen Idec Enters Into Agreement With Isis Pharma To Develop Antisense Drug For Myotonic Dystrophy 33
Biogen Idec Enters Into Co-Development Agreement With Isis Pharma 35
Licensing Agreements 37
PTC Therapeutics Enters into Licesing Agreement with Akcea Therapeutics 37
Akcea Therapeutics Enters into Licensing Agreement with Ionis Pharma 38
AstraZeneca Enters into Licensing Agreement with Ionis Pharma 40
Ionis Pharma Enters into License Agreement with Roche for IONIS-HTTRx 41
Janssen Biotech Enters into Licensing Agreement with Ionis Pharma 42
Ionis Pharma Enters into Licensing Agreement with Dynacure 43
Suzhou Ribo Enters into Licensing Agreement with Ionis Pharma 44
Biogen Exercises Option for Licensing Agreement with Ionis Pharma 45
Janssen Biotech Enters into Licensing Agreement with Ionis Pharma 46
Kastle Therapeutics Acquires Global Rights for KYNAMRO Injection from Ionis Pharma 47
Ionis Pharmaceuticals Enters Into Licensing Agreement with Glaxo Group and GlaxoSmithKline 48
Akcea Therapeutics Enters Into Licensing Agreement With Ionis Pharma 49
AstraZeneca Enters into Licensing Agreement with Isis Pharma 51
Bayer HealthCare Amends Licensing Agreement with Ionis Pharma 52
Xenon Pharma Exercises Option For Licensing Agreement With Isis Pharma For Antisense Drug XEN701 53
Astrazeneca Enters into Licensing Agreement with Isis Pharma 55
Equity Offering 56
Akcea Therapeutics Raises USD143.8 Million in IPO 56
Akcea Therapeutics Raises USD50 Million in Private Placement of Shares 58
Ionis Pharma Files Registration Statement for Public Offering of Shares for up to USD68.7 Million 59
Akcea Therapeutics Raises USD100 Million in Private Placement of Series A Preferred Stock 60
Isis Pharma Completes Public Offering Of Shares For USD 182.7 Million 61
Debt Offering 63
Isis Pharma Completes Private Placement of Notes for USD500 Million 63
Isis Pharma Completes Private Placement Of Convertible Senior Notes Due 2019 For USD 201 Million 65
Ionis Pharmaceuticals Inc-Key Competitors 66
Ionis Pharmaceuticals Inc-Key Employees 67
Ionis Pharmaceuticals Inc-Locations And Subsidiaries 68
Head Office 68
Other Locations & Subsidiaries 68
Joint Venture 69
Recent Developments 70
Financial Announcements 70
Aug 07, 2018: Ionis reports second quarter 2018 financial results 70
May 04, 2018: Ionis Announces First Quarter 2018 Financial Results 73
Feb 27, 2018: Ionis Announces Fourth Quarter and Full Year 2017 Financial Results 76
Nov 07, 2017: Ionis Pharmaceuticals Reports Financial Results and Highlights for Third Quarter 2017 79
Aug 08, 2017: Ionis Provides Improved 2017 Guidance Following Strong Financial Performance 81
May 09, 2017: Ionis Reports Financial Results and Highlights for First Quarter 2017 83
Feb 28, 2017: Ionis' 2016 Financial Results Outperform Financial Guidance 85
Jan 06, 2017: Ionis Pharmaceuticals Significantly Improves Upon 2016 Financial Guidance 89
Corporate Communications 90
Jun 18, 2018: Ionis Pharmaceuticals Names Damien McDevitt As Chief Business Officer 90
Nov 07, 2017: Ionis Announces Management Transitions 91
Sep 24, 2017: Ionis Pharmaceuticals appoints two new board members 92
Other Significant Developments 93
Jun 12, 2018: Akcea and Ambry Genetics to Launch hATTR Compass, a Genetic Testing Program for People with Suspected Hereditary ATTR Amyloidosis 93
Appendix 94
Methodology 94
About GlobalData 94
Contact Us 94
Disclaimer 94
List of Figure
List of Figures
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 2
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 2
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 2
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 2
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 7
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 8
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 9
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 10
Ionis Pharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 12
List of Table
List of Tables
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Key Facts, 2017 2
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 7
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 8
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 9
Ionis Pharmaceuticals Inc, Deals By Therapy Area, 2012 to YTD 2018 10
Ionis Pharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 12
Ionis Pharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 13
Ionis Pharma Recommends Stockholders to Reject Mini-Tender Offer of TRC Capital 16
Ionis Pharma Enters into Collaboration Agreement with Roche 17
Cerveau Technologies Enters into Research Agreement with Ionis Pharma 18
SRI International Enters into Reaserch Agreement with Ionis Pharma 19
Biogen and Ionis Pharma Enter into Agreement 20
Biogen and Ionis Pharma Enter into Agreement 21
Novartis Enters into Option Agreement with Ionis Pharma and Akcea Therapeutics 22
Ionis Pharma Enters into Agreement with Dynacure 24
Ionis Pharma Enters into Agreement with Cystic Fibrosis Foundation 25
Ionis Pharma Partners with University of Texas MD Anderson Cancer Center 26
Biogazelle Enters into Research Agreement with Isis Pharma 27
Isis Pharma Enters into Agreement with Janssen Biotech to Discover and Develop RNA-Targeted Therapeutics 28
Biogen Idec And Isis Pharma Enter Into R&D Agreement To Develop Treatments For Neurological Disorders 29
Roche Enters Into Co-Development Agreement With Isis Pharma For Huntington's Disease Treatment 30
AstraZeneca Expands Co-Development Agreement with Isis Pharma 31
Biogen Idec Enters Into Agreement With Isis Pharma To Develop Antisense Drugs For Neurological Disorders 32
Biogen Idec Enters Into Agreement With Isis Pharma To Develop Antisense Drug For Myotonic Dystrophy 33
Biogen Idec Enters Into Co-Development Agreement With Isis Pharma 35
PTC Therapeutics Enters into Licesing Agreement with Akcea Therapeutics 37
Akcea Therapeutics Enters into Licensing Agreement with Ionis Pharma 38
AstraZeneca Enters into Licensing Agreement with Ionis Pharma 40
Ionis Pharma Enters into License Agreement with Roche for IONIS-HTTRx 41
Janssen Biotech Enters into Licensing Agreement with Ionis Pharma 42
Ionis Pharma Enters into Licensing Agreement with Dynacure 43
Suzhou Ribo Enters into Licensing Agreement with Ionis Pharma 44
Biogen Exercises Option for Licensing Agreement with Ionis Pharma 45
Janssen Biotech Enters into Licensing Agreement with Ionis Pharma 46
Kastle Therapeutics Acquires Global Rights for KYNAMRO Injection from Ionis Pharma 47
Ionis Pharmaceuticals Enters Into Licensing Agreement with Glaxo Group and GlaxoSmithKline 48
Akcea Therapeutics Enters Into Licensing Agreement With Ionis Pharma 49
AstraZeneca Enters into Licensing Agreement with Isis Pharma 51
Bayer HealthCare Amends Licensing Agreement with Ionis Pharma 52
Xenon Pharma Exercises Option For Licensing Agreement With Isis Pharma For Antisense Drug XEN701 53
Astrazeneca Enters into Licensing Agreement with Isis Pharma 55
Akcea Therapeutics Raises USD143.8 Million in IPO 56
Akcea Therapeutics Raises USD50 Million in Private Placement of Shares 58
Ionis Pharma Files Registration Statement for Public Offering of Shares for up to USD68.7 Million 59
Akcea Therapeutics Raises USD100 Million in Private Placement of Series A Preferred Stock 60
Isis Pharma Completes Public Offering Of Shares For USD 182.7 Million 61
Isis Pharma Completes Private Placement of Notes for USD500 Million 63
Isis Pharma Completes Private Placement Of Convertible Senior Notes Due 2019 For USD 201 Million 65
Ionis Pharmaceuticals Inc, Key Competitors 66
Ionis Pharmaceuticals Inc, Key Employees 67
Ionis Pharmaceuticals Inc, Subsidiaries 68
Ionis Pharmaceuticals Inc, Joint Venture 69
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