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Malaria-Pipeline Review, H1 2015

Malaria-Pipeline Review, H1 2015


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Executive Summary

Malaria-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Malaria-Pipeline Review, H1 2015', provides an overview of the Malaria's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Malaria, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Malaria and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Malaria

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Malaria and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Malaria products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Malaria pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Malaria

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Malaria pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

Introduction 6

Malaria Overview 7

Therapeutics Development 8

Malaria-Therapeutics under Development by Companies 10

Malaria-Therapeutics under Investigation by Universities/Institutes 17

Malaria-Pipeline Products Glance 22

Malaria-Products under Development by Companies 26

Malaria-Products under Investigation by Universities/Institutes 34

Malaria-Companies Involved in Therapeutics Development 40

Malaria-Therapeutics Assessment 107

Drug Profiles 118

Malaria-Recent Pipeline Updates 348

Malaria-Dormant Projects 367

Malaria-Discontinued Products 376

Malaria-Product Development Milestones 379

Appendix 388

List of Tables

Number of Products under Development for Malaria, H1 2015 29

Number of Products under Development for Malaria-Comparative Analysis, H1 2015 30

Number of Products under Development by Companies, H1 2015 32

Number of Products under Development by Companies, H1 2015 (Contd..1) 33

Number of Products under Development by Companies, H1 2015 (Contd..2) 34

Number of Products under Development by Companies, H1 2015 (Contd..3) 35

Number of Products under Development by Companies, H1 2015 (Contd..4) 36

Number of Products under Development by Companies, H1 2015 (Contd..5) 37

Number of Products under Investigation by Universities/Institutes, H1 2015 39

Number of Products under Investigation by Universities/Institutes, H1 2015 (Contd..1) 40

Number of Products under Investigation by Universities/Institutes, H1 2015 (Contd..2) 41

Number of Products under Investigation by Universities/Institutes, H1 2015 (Contd..3) 42

Comparative Analysis by Late Stage Development, H1 2015 43

Comparative Analysis by Clinical Stage Development, H1 2015 44

Comparative Analysis by Early Stage Development, H1 2015 45

Comparative Analysis by Unknown Stage Development, H1 2015 46

Products under Development by Companies, H1 2015 47

Products under Development by Companies, H1 2015 (Contd..1) 48

Products under Development by Companies, H1 2015 (Contd..2) 49

Products under Development by Companies, H1 2015 (Contd..3) 50

Products under Development by Companies, H1 2015 (Contd..4) 51

Products under Development by Companies, H1 2015 (Contd..5) 52

Products under Development by Companies, H1 2015 (Contd..6) 53

Products under Development by Companies, H1 2015 (Contd..7) 54

Products under Investigation by Universities/Institutes, H1 2015 55

Products under Investigation by Universities/Institutes, H1 2015 (Contd..1) 56

Products under Investigation by Universities/Institutes, H1 2015 (Contd..2) 57

Products under Investigation by Universities/Institutes, H1 2015 (Contd..3) 58

Products under Investigation by Universities/Institutes, H1 2015 (Contd..4) 59

Products under Investigation by Universities/Institutes, H1 2015 (Contd..5) 60

Malaria-Pipeline by 4SC AG, H1 2015 61

Malaria-Pipeline by Acetylon Pharmaceuticals, Inc., H1 2015 62

Malaria-Pipeline by Actelion Ltd, H1 2015 63

Malaria-Pipeline by Agilvax, Inc., H1 2015 64

Malaria-Pipeline by Akshaya Bio Inc., H1 2015 65

Malaria-Pipeline by Amura Holdings Limited, H1 2015 66

Malaria-Pipeline by Artificial Cell Technologies, Inc., H1 2015 67

Malaria-Pipeline by AstraZeneca Plc, H1 2015 68

Malaria-Pipeline by Bharat Biotech International Limited, H1 2015 69

Malaria-Pipeline by Callaghan Innovation Research Ltd., H1 2015 70

Malaria-Pipeline by Carna Biosciences, Inc., H1 2015 71

Malaria-Pipeline by CEL-SCI Corporation, H1 2015 72

Malaria-Pipeline by Celgene Corporation, H1 2015 73

Malaria-Pipeline by Cellceutix Corporation, H1 2015 74

Malaria-Pipeline by Chong Kun Dang Pharmaceutical Corp., H1 2015 75

Malaria-Pipeline by Cilian AG, H1 2015 76

Malaria-Pipeline by Clevexel Pharma SAS, H1 2015 77

Malaria-Pipeline by Daiichi Sankyo Company, Limited, H1 2015 78

Malaria-Pipeline by DesignMedix, Inc., H1 2015 79

Malaria-Pipeline by Eisai Co., Ltd., H1 2015 80

Malaria-Pipeline by Genocea Biosciences, Inc., H1 2015 81

Malaria-Pipeline by GenVec, Inc., H1 2015 82

Malaria-Pipeline by Genzyme Corporation, H1 2015 83

Malaria-Pipeline by Georgia Tech Research Corporation, H1 2015 84

Malaria-Pipeline by GlaxoSmithKline Plc, H1 2015 85

Malaria-Pipeline by Hawaii Biotech, Inc., H1 2015 86

Malaria-Pipeline by iBio, Inc., H1 2015 87

Malaria-Pipeline by Imaxio SA, H1 2015 88

Malaria-Pipeline by Immtech Pharmaceuticals, Inc., H1 2015 89

Malaria-Pipeline by Immunitor, Inc., H1 2015 90

Malaria-Pipeline by Immunovaccine, Inc., H1 2015 91

Malaria-Pipeline by Inovio Pharmaceuticals, Inc., H1 2015 92

Malaria-Pipeline by IPCA Laboratories Limited, H1 2015 93

Malaria-Pipeline by iQur Limited, H1 2015 94

Malaria-Pipeline by IRBM Science Park SpA, H1 2015 95

Malaria-Pipeline by iThemba Pharmaceuticals (Pty) Ltd., H1 2015 96

Malaria-Pipeline by Jenrin Discovery, Inc., H1 2015 97

Malaria-Pipeline by Jomaa Pharma GmbH, H1 2015 98

Malaria-Pipeline by KAEL-GemVax Co., Ltd., H1 2015 99

Malaria-Pipeline by Kancera AB, H1 2015 100

Malaria-Pipeline by Lipotek Pty Ltd., H1 2015 101

Malaria-Pipeline by LondonPharma Ltd, H1 2015 102

Malaria-Pipeline by Merck KGaA, H1 2015 103

Malaria-Pipeline by MerLion Pharmaceuticals Pte Ltd, H1 2015 104

Malaria-Pipeline by Microbiotix, Inc., H1 2015 105

Malaria-Pipeline by Molplex Ltd., H1 2015 106

Malaria-Pipeline by Mucosis B.V., H1 2015 107

Malaria-Pipeline by Mymetics Corporation, H1 2015 108

Malaria-Pipeline by Novartis AG, H1 2015 109

Malaria-Pipeline by Panacela Labs, Inc., H1 2015 110

Malaria-Pipeline by PaxVax, H1 2015 111

Malaria-Pipeline by Pfenex Inc., H1 2015 112

Malaria-Pipeline by Pfizer Inc., H1 2015 113

Malaria-Pipeline by Raptor Pharmaceuticals Corp., H1 2015 114

Malaria-Pipeline by Rodos BioTarget GmbH, H1 2015 115

Malaria-Pipeline by Sanaria Inc., H1 2015 116

Malaria-Pipeline by Sanofi, H1 2015 117

Malaria-Pipeline by SATT Lutech SAS, H1 2015 118

Malaria-Pipeline by SEEK Group, H1 2015 119

Malaria-Pipeline by Selecta Biosciences, Inc., H1 2015 120

Malaria-Pipeline by Sigma-Tau Pharmaceuticals, Inc, H1 2015 121

Malaria-Pipeline by Sigma-Tau S.p.A., H1 2015 122

Malaria-Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 123

Malaria-Pipeline by Telormedix SA, H1 2015 124

Malaria-Pipeline by Vaccibody AS, H1 2015 125

Malaria-Pipeline by VLP Biotech, Inc., H1 2015 126

Malaria-Pipeline by Zydus Cadila Healthcare Limited, H1 2015 127

Assessment by Monotherapy Products, H1 2015 128

Assessment by Combination Products, H1 2015 129

Number of Products by Stage and Target, H1 2015 131

Number of Products by Stage and Mechanism of Action, H1 2015 134

Number of Products by Stage and Route of Administration, H1 2015 136

Number of Products by Stage and Molecule Type, H1 2015 138

Malaria Therapeutics-Recent Pipeline Updates, H1 2015 369

Malaria-Dormant Projects, H1 2015 388

Malaria-Dormant Projects (Contd..1), H1 2015 389

Malaria-Dormant Projects (Contd..2), H1 2015 390

Malaria-Dormant Projects (Contd..3), H1 2015 391

Malaria-Dormant Projects (Contd..4), H1 2015 392

Malaria-Dormant Projects (Contd..5), H1 2015 393

Malaria-Dormant Projects (Contd..6), H1 2015 394

Malaria-Dormant Projects (Contd..7), H1 2015 395

Malaria-Dormant Projects (Contd..8), H1 2015 396

Malaria-Discontinued Products, H1 2015 397

Malaria-Discontinued Products (Contd..1), H1 2015 398

Malaria-Discontinued Products (Contd..2), H1 2015 399

List of Figures

Number of Products under Development for Malaria, H1 2015 29

Number of Products under Development for Malaria-Comparative Analysis, H1 2015 30

Number of Products under Development by Companies, H1 2015 31

Number of Products under Investigation by Universities/Institutes, H1 2015 38

Comparative Analysis by Late Stage Development, H1 2015 43

Comparative Analysis by Clinical Stage Development, H1 2015 44

Comparative Analysis by Early Stage Products, H1 2015 45

Comparative Analysis by Unknown Stage Development, H1 2015 46

Assessment by Monotherapy Products, H1 2015 128

Number of Products by Top 10 Targets, H1 2015 130

Number of Products by Stage and Top 10 Targets, H1 2015 130

Number of Products by Top 10 Mechanism of Actions, H1 2015 133

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 133

Number of Products by Top 10 Routes of Administration, H1 2015 135

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 135

Number of Products by Top 10 Molecule Types, H1 2015 137

Number of Products by Stage and Top 10 Molecule Types, H1 2015 137

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4SC AG

Acetylon Pharmaceuticals, Inc.

Actelion Ltd

Agilvax, Inc.

Akshaya Bio Inc.

Amura Holdings Limited

Artificial Cell Technologies, Inc.

AstraZeneca Plc

Bharat Biotech International Limited

Callaghan Innovation Research Ltd.

Carna Biosciences, Inc.

CEL-SCI Corporation

Celgene Corporation

Cellceutix Corporation

Chong Kun Dang Pharmaceutical Corp.

Cilian AG

Clevexel Pharma SAS

Daiichi Sankyo Company, Limited

DesignMedix, Inc.

Eisai Co., Ltd.

Genocea Biosciences, Inc.

GenVec, Inc.

Genzyme Corporation

Georgia Tech Research Corporation

GlaxoSmithKline Plc

Hawaii Biotech, Inc.

iBio, Inc.

Imaxio SA

Immtech Pharmaceuticals, Inc.

Immunitor, Inc.

Immunovaccine, Inc.

Inovio Pharmaceuticals, Inc.

IPCA Laboratories Limited

iQur Limited

IRBM Science Park SpA

iThemba Pharmaceuticals (Pty) Ltd.

Jenrin Discovery, Inc.

Jomaa Pharma GmbH

KAEL-GemVax Co., Ltd.

Kancera AB

Lipotek Pty Ltd.

LondonPharma Ltd

Merck KGaA

MerLion Pharmaceuticals Pte Ltd

Microbiotix, Inc.

Molplex Ltd.

Mucosis B.V.

Mymetics Corporation

Novartis AG

Panacela Labs, Inc.

PaxVax

Pfenex Inc.

Pfizer Inc.

Raptor Pharmaceuticals Corp.

Rodos BioTarget GmbH

Sanaria Inc.

Sanofi

SATT Lutech SAS

SEEK Group

Selecta Biosciences, Inc.

Sigma-Tau Pharmaceuticals, Inc

Sigma-Tau S.p.A.

Takeda Pharmaceutical Company Limited

Telormedix SA

Vaccibody AS

VLP Biotech, Inc.

Zydus Cadila Healthcare Limited

Malaria Therapeutic Products under Development, Key Players in Malaria Therapeutics, Malaria Pipeline Overview, Malaria Pipeline, Malaria Pipeline Assessment


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