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Menopausal Hot Flashes-Pipeline Review, H1 2015

Menopausal Hot Flashes-Pipeline Review, H1 2015


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Executive Summary

Menopausal Hot Flashes-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Menopausal Hot Flashes-Pipeline Review, H1 2015', provides an overview of the Menopausal Hot Flashes's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Menopausal Hot Flashes, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Menopausal Hot Flashes and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Menopausal Hot Flashes

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Menopausal Hot Flashes and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Menopausal Hot Flashes products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Menopausal Hot Flashes pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Menopausal Hot Flashes

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Menopausal Hot Flashes pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 5

Introduction 6

Global Markets Direct Report Coverage 6

Menopausal Hot Flashes Overview 7

Therapeutics Development 8

Pipeline Products for Menopausal Hot Flashes-Overview 8

Pipeline Products for Menopausal Hot Flashes-Comparative Analysis 9

Menopausal Hot Flashes-Therapeutics under Development by Companies 10

Menopausal Hot Flashes-Pipeline Products Glance 11

Late Stage Products 11

Clinical Stage Products 12

Early Stage Products 13

Unknown Stage Products 14

Menopausal Hot Flashes-Products under Development by Companies 15

Menopausal Hot Flashes-Companies Involved in Therapeutics Development 16

Amgen Inc. 16

Edgemont Pharmaceuticals, LLC 17

EndoCeutics, Inc. 18

Pantarhei Bioscience BV 19

Pherin Pharmaceuticals, Inc. 20

Radius Health, Inc. 21

Menopausal Hot Flashes-Therapeutics Assessment 22

Assessment by Monotherapy Products 22

Assessment by Combination Products 23

Assessment by Target 24

Assessment by Mechanism of Action 26

Assessment by Route of Administration 28

Assessment by Molecule Type 30

Drug Profiles 32

AMG-334-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

EDG-007-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

esterol-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

FP-101-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

HBN-2-Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

homatropine methylbromide-Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

MNGX-100-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

prasterone + acolbifene hydrochloride-Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

Q-122-Drug Profile 41

Product Description 41

Mechanism of Action 41

R&D Progress 41

RAD-1901-Drug Profile 42

Product Description 42

Mechanism of Action 42

R&D Progress 42

Salubrin-HF-Drug Profile 44

Product Description 44

Mechanism of Action 44

R&D Progress 44

Menopausal Hot Flashes-Recent Pipeline Updates 45

Menopausal Hot Flashes-Dormant Projects 48

Menopausal Hot Flashes-Discontinued Products 49

Menopausal Hot Flashes-Product Development Milestones 50

Featured News & Press Releases 50

Sep 26, 2012: Eaton Scientific Highlights International Potential For Tropine 3 As Globally Accepted Non-Hormonal Treatment For Hot Flash Symptoms 50

Sep 25, 2012: Eaton Scientific Provides Outline On Market Potential Of Tropine 3 For Non-Hormonal Treatment Of Hot Flashes 50

Sep 13, 2012: Eaton Scientific Teams Up With Urologist Dr Jennifer Berman To Advance Tropine 3 Trials And Marketing 50

Sep 06, 2012: Eaton Scientific Completes Study Protocol For Phase I/II Study Of Tropine 3 For Treatment Of Hot Flashes 51

Sep 04, 2012: Eaton Scientific Enters Agreement With RoxSan Pharmacy To Provide Tropine 3 For Upcoming Clinical Trial Participants 51

Aug 28, 2012: Eaton Scientific Announces Clinical Trial Plans For Tropine 3 For Treatment Of Hot Flashes In Menopausal Women 52

Jun 19, 2010: Radius Presents Positive Phase IIa Study Results Of RAD1901 In Reducing Menopausal Hot Flashes 52

Jun 08, 2008: Radius Presents Preclinical Study Of RAD1901 At The Endocrine Society 2007 Annual Meeting 53

Appendix 54

Methodology 54

Coverage 54

Secondary Research 54

Primary Research 54

Expert Panel Validation 54

Contact Us 54

Disclaimer 55

List of Tables

Number of Products under Development for Menopausal Hot Flashes, H1 2015 8

Number of Products under Development for Menopausal Hot Flashes-Comparative Analysis, H1 2015 9

Number of Products under Development by Companies, H1 2015 10

Comparative Analysis by Late Stage Development, H1 2015 11

Comparative Analysis by Clinical Stage Development, H1 2015 12

Comparative Analysis by Early Stage Development, H1 2015 13

Comparative Analysis by Unknown Stage Development, H1 2015 14

Products under Development by Companies, H1 2015 15

Menopausal Hot Flashes-Pipeline by Amgen Inc., H1 2015 16

Menopausal Hot Flashes-Pipeline by Edgemont Pharmaceuticals, LLC, H1 2015 17

Menopausal Hot Flashes-Pipeline by EndoCeutics, Inc., H1 2015 18

Menopausal Hot Flashes-Pipeline by Pantarhei Bioscience BV, H1 2015 19

Menopausal Hot Flashes-Pipeline by Pherin Pharmaceuticals, Inc., H1 2015 20

Menopausal Hot Flashes-Pipeline by Radius Health, Inc., H1 2015 21

Assessment by Monotherapy Products, H1 2015 22

Assessment by Combination Products, H1 2015 23

Number of Products by Stage and Target, H1 2015 25

Number of Products by Stage and Mechanism of Action, H1 2015 27

Number of Products by Stage and Route of Administration, H1 2015 29

Number of Products by Stage and Molecule Type, H1 2015 31

Menopausal Hot Flashes Therapeutics-Recent Pipeline Updates, H1 2015 45

Menopausal Hot Flashes-Dormant Projects, H1 2015 48

Menopausal Hot Flashes-Discontinued Products, H1 2015 49

List of Figures

Number of Products under Development for Menopausal Hot Flashes, H1 2015 8

Number of Products under Development for Menopausal Hot Flashes-Comparative Analysis, H1 2015 9

Number of Products under Development by Companies, H1 2015 10

Comparative Analysis by Clinical Stage Development, H1 2015 12

Assessment by Monotherapy Products, H1 2015 22

Number of Products by Top 10 Targets, H1 2015 24

Number of Products by Stage and Top 10 Targets, H1 2015 25

Number of Products by Top 10 Mechanism of Actions, H1 2015 26

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 27

Number of Products by Top 10 Routes of Administration, H1 2015 28

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 29

Number of Products by Top 10 Molecule Types, H1 2015 30

Number of Products by Stage and Top 10 Molecule Types, H1 2015 31

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Amgen Inc.

Edgemont Pharmaceuticals, LLC

EndoCeutics, Inc.

Pantarhei Bioscience BV

Pherin Pharmaceuticals, Inc.

Radius Health, Inc.

Menopausal Hot Flashes Therapeutic Products under Development, Key Players in Menopausal Hot Flashes Therapeutics, Menopausal Hot Flashes Pipeline Overview, Menopausal Hot Flashes Pipeline, Menopausal Hot Flashes Pipeline Assessment


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