Muscle Spasticity-Pipeline Review, H2 2015

Muscle Spasticity-Pipeline Review, H2 2015


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Executive Summary

Muscle Spasticity-Pipeline Review, H2 2015

Summary

Global Markets Direct's, 'Muscle Spasticity-Pipeline Review, H2 2015', provides an overview of the Muscle Spasticity's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Muscle Spasticity, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Muscle Spasticity and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Muscle Spasticity

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Muscle Spasticity and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Muscle Spasticity products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Muscle Spasticity pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Muscle Spasticity

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Muscle Spasticity pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline



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Ken Research
Ankur Gupta, Head Marketing & Communications

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Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Muscle Spasticity Overview 6

Therapeutics Development 7

Pipeline Products for Muscle Spasticity-Overview 7

Pipeline Products for Muscle Spasticity-Comparative Analysis 8

Muscle Spasticity-Therapeutics under Development by Companies 9

Muscle Spasticity-Pipeline Products Glance 10

Late Stage Products 10

Clinical Stage Products 11

Early Stage Products 12

Muscle Spasticity-Products under Development by Companies 13

Muscle Spasticity-Companies Involved in Therapeutics Development 14

Daewoong Pharmaceutical Co., Ltd. 14

Ipsen S.A. 15

OBI Pharma, Inc. 16

Sanochemia Pharmazeutika AG 17

Sun Pharma Advanced Research Company Ltd. 18

Muscle Spasticity-Therapeutics Assessment 19

Assessment by Monotherapy Products 19

Assessment by Target 20

Assessment by Mechanism of Action 22

Assessment by Route of Administration 24

Assessment by Molecule Type 26

Drug Profiles 28

abobotulinumtoxin A-Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

baclofen ER-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

NB-2221-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

OBI-858-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

onabotulinumtoxin A-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

tolperisone-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Muscle Spasticity-Recent Pipeline Updates 36

Muscle Spasticity-Dormant Projects 39

Muscle Spasticity-Discontinued Products 40

Muscle Spasticity-Product Development Milestones 41

Featured News & Press Releases 41

Jul 16, 2015: Ipsen Biopharmaceuticals Announces FDA Approval of Dysport (abobotulinumtoxinA) for Injection in the Treatment of Upper Limb Spasticity in Adults in the United States 41

Jan 26, 2015: Ipsen announces topline results of two double-blind phase III studies of Dysport in lower limb spasticity in children and in adults 42

Nov 28, 2014: Ipsen Announces FDA Acceptance of Filing for Dysport in the Treatment of Upper Limb Spasticity in Adult Patients 44

Nov 14, 2014: Ipsen Biopharmaceuticals Presents Dysport (abobotulinumtoxinA) Data at American Academy of Physical Medicine and Rehabilitation Annual Assembly 44

Jul 11, 2014: Ipsen and Galderma become exclusive partners for development and marketing of neurotoxins in the US, Canada, Brazil and Europe 46

Apr 12, 2014: Ipsen announces a first set of results on positive phase III clinical study of Dysport in the treatment of adults suffering from Upper Limb Spasticity at the 8th World Congress for NeuroRehabilitation in Istanbul 46

Dec 17, 2013: Ipsen announces positive initial results from the international double-blind clinical phase III study of Dysport in the treatment of Adults suffering from Upper Limb Spasticity 48

Appendix 50

Methodology 50

Coverage 50

Secondary Research 50

Primary Research 50

Expert Panel Validation 50

Contact Us 50

Disclaimer 51

List of Tables

Number of Products under Development for Muscle Spasticity, H2 2015 7

Number of Products under Development for Muscle Spasticity-Comparative Analysis, H2 2015 8

Number of Products under Development by Companies, H2 2015 9

Comparative Analysis by Late Stage Development, H2 2015 10

Comparative Analysis by Clinical Stage Development, H2 2015 11

Comparative Analysis by Early Stage Development, H2 2015 12

Products under Development by Companies, H2 2015 13

Muscle Spasticity-Pipeline by Daewoong Pharmaceutical Co., Ltd., H2 2015 14

Muscle Spasticity-Pipeline by Ipsen S.A., H2 2015 15

Muscle Spasticity-Pipeline by OBI Pharma, Inc., H2 2015 16

Muscle Spasticity-Pipeline by Sanochemia Pharmazeutika AG, H2 2015 17

Muscle Spasticity-Pipeline by Sun Pharma Advanced Research Company Ltd., H2 2015 18

Assessment by Monotherapy Products, H2 2015 19

Number of Products by Stage and Target, H2 2015 21

Number of Products by Stage and Mechanism of Action, H2 2015 23

Number of Products by Stage and Route of Administration, H2 2015 25

Number of Products by Stage and Molecule Type, H2 2015 27

Muscle Spasticity Therapeutics-Recent Pipeline Updates, H2 2015 36

Muscle Spasticity-Dormant Projects, H2 2015 39

Muscle Spasticity-Discontinued Products, H2 2015 40

List of Figures

Number of Products under Development for Muscle Spasticity, H2 2015 7

Number of Products under Development for Muscle Spasticity-Comparative Analysis, H2 2015 8

Number of Products under Development by Companies, H2 2015 9

Assessment by Monotherapy Products, H2 2015 19

Number of Products by Top 10 Targets, H2 2015 20

Number of Products by Stage and Top 10 Targets, H2 2015 20

Number of Products by Top 10 Mechanism of Actions, H2 2015 22

Number of Products by Stage and Top 10 Mechanism of Actions, H2 2015 22

Number of Products by Top 10 Routes of Administration, H2 2015 24

Number of Products by Stage and Top 10 Routes of Administration, H2 2015 24

Number of Products by Top 10 Molecule Types, H2 2015 26

Number of Products by Stage and Top 10 Molecule Types, H2 2015 26

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Daewoong Pharmaceutical Co., Ltd.

Ipsen S.A.

OBI Pharma, Inc.

Sanochemia Pharmazeutika AG

Sun Pharma Advanced Research Company Ltd

Muscle Spasticity Therapeutic Products under Development, Key Players in Muscle Spasticity Therapeutics, Muscle Spasticity Pipeline Overview, Muscle Spasticity Pipeline, Muscle Spasticity Pipeline Assessment

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