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Pancreatitis-Pipeline Review, H1 2015

Pancreatitis-Pipeline Review, H1 2015


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Executive Summary

Pancreatitis-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Pancreatitis-Pipeline Review, H1 2015', provides an overview of the Pancreatitis's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Pancreatitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Pancreatitis and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Pancreatitis

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Pancreatitis and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Pancreatitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Pancreatitis pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Pancreatitis

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Pancreatitis pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Pancreatitis Overview 6

Therapeutics Development 7

Pipeline Products for Pancreatitis-Overview 7

Pipeline Products for Pancreatitis-Comparative Analysis 8

Pancreatitis-Therapeutics under Development by Companies 9

Pancreatitis-Pipeline Products Glance 10

Clinical Stage Products 10

Early Stage Products 11

Pancreatitis-Products under Development by Companies 12

Pancreatitis-Companies Involved in Therapeutics Development 13

D-Pharm Ltd. 13

Dynavax Technologies Corporation 14

GlaxoSmithKline plc 15

Pharming Group N.V. 16

Pancreatitis-Therapeutics Assessment 17

Assessment by Monotherapy Products 17

Assessment by Target 18

Assessment by Mechanism of Action 20

Assessment by Route of Administration 22

Assessment by Molecule Type 23

Drug Profiles 25

AEM-28-02-Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

C1 esterase inhibitor (recombinant)-Drug Profile 26

Product Description 26

Mechanism of Action 26

R&D Progress 26

DP-b99-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

Drugs to Inhibit Kynurenine 3-Monooxygenase for Acute Pancreatitis-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

DV-1179-Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

GSK-6288B-Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

PZ-235-Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

SP-20201-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

SUN-102-Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

Pancreatitis-Recent Pipeline Updates 41

Pancreatitis-Dormant Projects 47

Pancreatitis-Discontinued Products 49

Pancreatitis-Product Development Milestones 50

Featured News & Press Releases 50

Jun 12, 2014: D-Pharm's DP-b99 Prevents Abnormal Neuronal Plasticity and Pathological Brain Reorganization 50

Jan 14, 2014: D-Pharm Announces Recruitment of the First Patient Into Its Phase 2 Clinical Trial With DP-b99 in Acute High-Risk Pancreatitis 50

Nov 21, 2013: D-Pharm starts Phase 2 Clinical Study with DP-b99 in Acute High-Risk Pancreatitis Patients 51

Oct 14, 2013: D-Pharm Schedules Investigators Meeting to Discuss Protocol of Phase 2 Clinical Study of DP-b99 for Acute High-Risk Pancreatitis 51

Appendix 53

Methodology 53

Coverage 53

Secondary Research 53

Primary Research 53

Expert Panel Validation 53

Contact Us 53

Disclaimer 54

List of Tables

Number of Products under Development for Pancreatitis, H1 2015 7

Number of Products under Development for Pancreatitis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Comparative Analysis by Early Stage Development, H1 2015 11

Products under Development by Companies, H1 2015 12

Pancreatitis-Pipeline by D-Pharm Ltd., H1 2015 13

Pancreatitis-Pipeline by Dynavax Technologies Corporation, H1 2015 14

Pancreatitis-Pipeline by GlaxoSmithKline plc, H1 2015 15

Pancreatitis-Pipeline by Pharming Group N.V., H1 2015 16

Assessment by Monotherapy Products, H1 2015 17

Number of Products by Stage and Target, H1 2015 19

Number of Products by Stage and Mechanism of Action, H1 2015 21

Number of Products by Stage and Route of Administration, H1 2015 22

Number of Products by Stage and Molecule Type, H1 2015 24

Pancreatitis Therapeutics-Recent Pipeline Updates, H1 2015 41

Pancreatitis-Dormant Projects, H1 2015 47

Pancreatitis-Dormant Projects (Contd..1), H1 2015 48

Pancreatitis-Discontinued Products, H1 2015 49

List of Figures

Number of Products under Development for Pancreatitis, H1 2015 7

Number of Products under Development for Pancreatitis-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Comparative Analysis by Early Stage Products, H1 2015 11

Assessment by Monotherapy Products, H1 2015 17

Number of Products by Top 10 Targets, H1 2015 18

Number of Products by Stage and Top 10 Targets, H1 2015 19

Number of Products by Top 10 Mechanism of Actions, H1 2015 20

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 21

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 22

Number of Products by Top 10 Molecule Types, H1 2015 23

Number of Products by Stage and Top 10 Molecule Types, H1 2015 24

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D-Pharm Ltd.

Dynavax Technologies Corporation

GlaxoSmithKline plc

Pharming Group N.V.

Pancreatitis Therapeutic Products under Development, Key Players in Pancreatitis Therapeutics, Pancreatitis Pipeline Overview, Pancreatitis Pipeline, Pancreatitis Pipeline Assessment


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