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Psoriasis-Pipeline Review, H1 2015

Psoriasis-Pipeline Review, H1 2015


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Executive Summary

Psoriasis-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Psoriasis-Pipeline Review, H1 2015', provides an overview of the Psoriasis's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Psoriasis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Psoriasis and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Psoriasis

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Psoriasis and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Psoriasis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Psoriasis pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Psoriasis

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Psoriasis pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

Introduction 9

Psoriasis Overview 10

Therapeutics Development 11

Psoriasis-Therapeutics under Development by Companies 13

Psoriasis-Therapeutics under Investigation by Universities/Institutes 25

Psoriasis-Pipeline Products Glance 26

Psoriasis-Products under Development by Companies 29

Psoriasis-Products under Investigation by Universities/Institutes 48

Psoriasis-Companies Involved in Therapeutics Development 49

Psoriasis-Therapeutics Assessment 179

Drug Profiles 196

Psoriasis-Recent Pipeline Updates 477

Psoriasis-Dormant Projects 586

Psoriasis-Dormant Projects 586

Psoriasis-Discontinued Products 609

Psoriasis-Product Development Milestones 614

Appendix 621

List of Tables

Number of Products under Development for Psoriasis, H1 2015 35

Number of Products under Development for Psoriasis-Comparative Analysis, H1 2015 36

Number of Products under Development by Companies, H1 2015 38

Number of Products under Development by Companies, H1 2015 (Contd..1) 39

Number of Products under Development by Companies, H1 2015 (Contd..2) 40

Number of Products under Development by Companies, H1 2015 (Contd..3) 41

Number of Products under Development by Companies, H1 2015 (Contd..4) 42

Number of Products under Development by Companies, H1 2015 (Contd..5) 43

Number of Products under Development by Companies, H1 2015 (Contd..6) 44

Number of Products under Development by Companies, H1 2015 (Contd..7) 45

Number of Products under Development by Companies, H1 2015 (Contd..8) 46

Number of Products under Development by Companies, H1 2015 (Contd..9) 47

Number of Products under Development by Companies, H1 2015 (Contd..10) 48

Number of Products under Investigation by Universities/Institutes, H1 2015 49

Comparative Analysis by Late Stage Development, H1 2015 50

Comparative Analysis by Clinical Stage Development, H1 2015 51

Comparative Analysis by Early Stage Development, H1 2015 52

Products under Development by Companies, H1 2015 53

Products under Development by Companies, H1 2015 (Contd..1) 54

Products under Development by Companies, H1 2015 (Contd..2) 55

Products under Development by Companies, H1 2015 (Contd..3) 56

Products under Development by Companies, H1 2015 (Contd..4) 57

Products under Development by Companies, H1 2015 (Contd..5) 58

Products under Development by Companies, H1 2015 (Contd..6) 59

Products under Development by Companies, H1 2015 (Contd..7) 60

Products under Development by Companies, H1 2015 (Contd..8) 61

Products under Development by Companies, H1 2015 (Contd..9) 62

Products under Development by Companies, H1 2015 (Contd..10) 63

Products under Development by Companies, H1 2015 (Contd..11) 64

Products under Development by Companies, H1 2015 (Contd..12) 65

Products under Development by Companies, H1 2015 (Contd..13) 66

Products under Development by Companies, H1 2015 (Contd..14) 67

Products under Development by Companies, H1 2015 (Contd..15) 68

Products under Development by Companies, H1 2015 (Contd..16) 69

Products under Development by Companies, H1 2015 (Contd..17) 70

Products under Development by Companies, H1 2015 (Contd..18) 71

Products under Investigation by Universities/Institutes, H1 2015 72

Psoriasis-Pipeline by 4SC AG, H1 2015 73

Psoriasis-Pipeline by AbGenomics International, Inc., H1 2015 74

Psoriasis-Pipeline by Acceleron Pharma, Inc., H1 2015 75

Psoriasis-Pipeline by Actelion Ltd, H1 2015 76

Psoriasis-Pipeline by Addex Therapeutics Ltd, H1 2015 77

Psoriasis-Pipeline by Advinus Therapeutics Ltd., H1 2015 78

Psoriasis-Pipeline by Ajinomoto Pharmaceuticals Co., Ltd., H1 2015 79

Psoriasis-Pipeline by AlbireoPharma, H1 2015 80

Psoriasis-Pipeline by Allozyne, Inc., H1 2015 81

Psoriasis-Pipeline by Almirall, S.A., H1 2015 82

Psoriasis-Pipeline by AlphaMab Co., Ltd, H1 2015 83

Psoriasis-Pipeline by Amgen Inc., H1 2015 84

Psoriasis-Pipeline by Anacor Pharmaceuticals, Inc., H1 2015 85

Psoriasis-Pipeline by Apexigen, Inc., H1 2015 86

Psoriasis-Pipeline by ApoPharma Inc., H1 2015 87

Psoriasis-Pipeline by Arena Pharmaceuticals, Inc., H1 2015 88

Psoriasis-Pipeline by Argos Therapeutics, Inc., H1 2015 89

Psoriasis-Pipeline by Arrien Pharmaceuticals, LLC, H1 2015 90

Psoriasis-Pipeline by AuraSense Therapeutics, LLC, H1 2015 91

Psoriasis-Pipeline by Avesthagen Limited, H1 2015 92

Psoriasis-Pipeline by Avexxin AS, H1 2015 93

Psoriasis-Pipeline by Basilea Pharmaceutica AG, H1 2015 94

Psoriasis-Pipeline by BIOCAD, H1 2015 95

Psoriasis-Pipeline by Biocon Limited, H1 2015 96

Psoriasis-Pipeline by Bionomics Limited, H1 2015 97

Psoriasis-Pipeline by Biotest AG, H1 2015 98

Psoriasis-Pipeline by Biotie Therapies Corp., H1 2015 99

Psoriasis-Pipeline by Boehringer Ingelheim GmbH, H1 2015 100

Psoriasis-Pipeline by Brickell Biotech, Inc., H1 2015 101

Psoriasis-Pipeline by Can-Fite BioPharma Ltd., H1 2015 102

Psoriasis-Pipeline by Celgene Corporation, H1 2015 103

Psoriasis-Pipeline by Cellceutix Corporation, H1 2015 104

Psoriasis-Pipeline by Celltrion, Inc., H1 2015 105

Psoriasis-Pipeline by ChemoCentryx, Inc., H1 2015 106

Psoriasis-Pipeline by ChironWells GmbH, H1 2015 107

Psoriasis-Pipeline by Circassia Pharmaceuticals plc, H1 2015 108

Psoriasis-Pipeline by Coherus BioSciences, Inc., H1 2015 109

Psoriasis-Pipeline by Compugen Ltd., H1 2015 110

Psoriasis-Pipeline by Convoy Therapeutics, Inc., H1 2015 111

Psoriasis-Pipeline by Covagen AG, H1 2015 112

Psoriasis-Pipeline by Creabilis SA, H1 2015 113

Psoriasis-Pipeline by Crescendo Biologics Limited, H1 2015 114

Psoriasis-Pipeline by Delenex Therapeutics AG, H1 2015 115

Psoriasis-Pipeline by Deltanoid Pharmaceuticals Inc., H1 2015 116

Psoriasis-Pipeline by Dermira Inc., H1 2015 117

Psoriasis-Pipeline by Effimune SAS, H1 2015 118

Psoriasis-Pipeline by Eli Lilly and Company, H1 2015 119

Psoriasis-Pipeline by Epirus Biopharmaceuticals, Inc., H1 2015 120

Psoriasis-Pipeline by Farmacija d.o.o. Tuzla, H1 2015 121

Psoriasis-Pipeline by Fibrocell Science, Inc., H1 2015 122

Psoriasis-Pipeline by Foamix Pharmaceuticals Ltd., H1 2015 123

Psoriasis-Pipeline by Forward Pharma A/S, H1 2015 124

Psoriasis-Pipeline by Gem Pharmaceuticals, LLC, H1 2015 125

Psoriasis-Pipeline by Gene Signal International SA, H1 2015 126

Psoriasis-Pipeline by Genentech, Inc., H1 2015 127

Psoriasis-Pipeline by Genor BioPharma Co., Ltd., H1 2015 128

Psoriasis-Pipeline by GlaxoSmithKline plc, H1 2015 129

Psoriasis-Pipeline by GliaCure Inc., H1 2015 130

Psoriasis-Pipeline by GlycoMar Limited, H1 2015 131

Psoriasis-Pipeline by Grupo Ferrer Internacional, S.A., H1 2015 132

Psoriasis-Pipeline by Hydra Biosciences, Inc., H1 2015 133

Psoriasis-Pipeline by Idera Pharmaceuticals, Inc., H1 2015 134

Psoriasis-Pipeline by Immune Response BioPharma, Inc., H1 2015 135

Psoriasis-Pipeline by Invion Limited, H1 2015 136

Psoriasis-Pipeline by ISDIN, H1 2015 137

Psoriasis-Pipeline by Johnson & Johnson, H1 2015 138

Psoriasis-Pipeline by Kadmon Corporation, LLC, H1 2015 139

Psoriasis-Pipeline by KaloBios Pharmaceuticals, Inc., H1 2015 140

Psoriasis-Pipeline by Kineta, Inc., H1 2015 141

Psoriasis-Pipeline by Kinex Pharmaceuticals, LLC, H1 2015 142

Psoriasis-Pipeline by Kyowa Hakko Kirin Co., Ltd., H1 2015 143

Psoriasis-Pipeline by Lee's Pharmaceutical Holdings Limited, H1 2015 144

Psoriasis-Pipeline by LegoChem Biosciences, Inc, H1 2015 145

Psoriasis-Pipeline by LEO Pharma A/S, H1 2015 146

Psoriasis-Pipeline by Lipidor AB, H1 2015 147

Psoriasis-Pipeline by Lupin Limited, H1 2015 148

Psoriasis-Pipeline by Lycera Corp., H1 2015 149

Psoriasis-Pipeline by Mabion SA, H1 2015 150

Psoriasis-Pipeline by Maruho Co., Ltd., H1 2015 151

Psoriasis-Pipeline by MediGene AG, H1 2015 152

Psoriasis-Pipeline by Merck KGaA, H1 2015 153

Psoriasis-Pipeline by Mitsubishi Tanabe Pharma Corporation, H1 2015 154

Psoriasis-Pipeline by NovaLead Pharma Pvt. Ltd., H1 2015 155

Psoriasis-Pipeline by Novartis AG, H1 2015 156

Psoriasis-Pipeline by Oncobiologics, Inc., H1 2015 157

Psoriasis-Pipeline by Ono Pharmaceutical Co., Ltd., H1 2015 158

Psoriasis-Pipeline by OPKO Health, Inc., H1 2015 159

Psoriasis-Pipeline by Panacea Biotec Limited, H1 2015 160

Psoriasis-Pipeline by Pfizer Inc., H1 2015 161

Psoriasis-Pipeline by Pharis Biotec GmbH, H1 2015 162

Psoriasis-Pipeline by Pharmedartis GmbH, H1 2015 163

Psoriasis-Pipeline by Phenex Pharmaceuticals AG, H1 2015 164

Psoriasis-Pipeline by Pieris AG, H1 2015 165

Psoriasis-Pipeline by PinCell srl, H1 2015 166

Psoriasis-Pipeline by Promius Pharma, LLC, H1 2015 167

Psoriasis-Pipeline by Protalix BioTherapeutics, Inc., H1 2015 168

Psoriasis-Pipeline by Prothena Corporation plc, H1 2015 169

Psoriasis-Pipeline by Provectus Biopharmaceuticals, Inc., H1 2015 170

Psoriasis-Pipeline by PurGenesis Technologies Inc., H1 2015 171

Psoriasis-Pipeline by R-Tech Ueno, Ltd., H1 2015 172

Psoriasis-Pipeline by RedHill Biopharma Ltd., H1 2015 173

Psoriasis-Pipeline by RestorGenex Corporation, H1 2015 174

Psoriasis-Pipeline by Rigel Pharmaceuticals, Inc., H1 2015 175

Psoriasis-Pipeline by Salix Pharmaceuticals Ltd., H1 2015 176

Psoriasis-Pipeline by Sandoz International GmbH, H1 2015 177

Psoriasis-Pipeline by Sareum Holdings plc, H1 2015 178

Psoriasis-Pipeline by Selvita SA, H1 2015 179

Psoriasis-Pipeline by Sigmoid Pharma Limited, H1 2015 180

Psoriasis-Pipeline by Soligenix, Inc., H1 2015 181

Psoriasis-Pipeline by Spherium Biomed S.L., H1 2015 182

Psoriasis-Pipeline by sterna biologicals Gmbh & Co KG, H1 2015 183

Psoriasis-Pipeline by Sun Pharma Advanced Research Company Ltd., H1 2015 184

Psoriasis-Pipeline by Sun Pharmaceutical Industries Inc., H1 2015 185

Psoriasis-Pipeline by SWITCH Biotech LLC, H1 2015 186

Psoriasis-Pipeline by Syntrix Biosystems, Inc., H1 2015 187

Psoriasis-Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 188

Psoriasis-Pipeline by Telormedix SA, H1 2015 189

Psoriasis-Pipeline by TetraLogic Pharmaceuticals, H1 2015 190

Psoriasis-Pipeline by Teva Pharmaceutical Industries Limited, H1 2015 191

Psoriasis-Pipeline by Therapix Biosciences Ltd, H1 2015 192

Psoriasis-Pipeline by Tolero Pharmaceuticals, Inc., H1 2015 193

Psoriasis-Pipeline by UCB S.A., H1 2015 194

Psoriasis-Pipeline by Uni-Bio Science Group Ltd., H1 2015 195

Psoriasis-Pipeline by Valeant Pharmaceuticals International, Inc., H1 2015 196

Psoriasis-Pipeline by Virobay Inc., H1 2015 197

Psoriasis-Pipeline by Vitae Pharmaceuticals, Inc., H1 2015 198

Psoriasis-Pipeline by Welichem Biotech Inc., H1 2015 199

Psoriasis-Pipeline by XBiotech USA, Inc., H1 2015 200

Psoriasis-Pipeline by XenoPort, Inc., H1 2015 201

Psoriasis-Pipeline by Ziarco Pharma Ltd, H1 2015 202

Assessment by Monotherapy Products, H1 2015 203

Assessment by Combination Products, H1 2015 204

Number of Products by Stage and Target, H1 2015 206

Number of Products by Stage and Mechanism of Action, H1 2015 212

Number of Products by Stage and Route of Administration, H1 2015 217

Number of Products by Stage and Molecule Type, H1 2015 219

Psoriasis Therapeutics-Recent Pipeline Updates, H1 2015 501

Psoriasis-Dormant Projects, H1 2015 610

Psoriasis-Dormant Projects (Contd..1), H1 2015 611

Psoriasis-Dormant Projects (Contd..2), H1 2015 612

Psoriasis-Dormant Projects (Contd..3), H1 2015 613

Psoriasis-Dormant Projects (Contd..4), H1 2015 614

Psoriasis-Dormant Projects (Contd..5), H1 2015 615

Psoriasis-Dormant Projects (Contd..6), H1 2015 616

Psoriasis-Dormant Projects (Contd..7), H1 2015 617

Psoriasis-Dormant Projects (Contd..8), H1 2015 618

Psoriasis-Dormant Projects (Contd..9), H1 2015 619

Psoriasis-Dormant Projects (Contd..10), H1 2015 620

Psoriasis-Dormant Projects (Contd..11), H1 2015 621

Psoriasis-Dormant Projects (Contd..12), H1 2015 622

Psoriasis-Dormant Projects (Contd..13), H1 2015 623

Psoriasis-Dormant Projects (Contd..14), H1 2015 624

Psoriasis-Dormant Projects (Contd..15), H1 2015 625

Psoriasis-Dormant Projects (Contd..16), H1 2015 626

Psoriasis-Dormant Projects (Contd..17), H1 2015 627

Psoriasis-Dormant Projects (Contd..18), H1 2015 628

Psoriasis-Dormant Projects (Contd..19), H1 2015 629

Psoriasis-Dormant Projects (Contd..20), H1 2015 630

Psoriasis-Dormant Projects (Contd..21), H1 2015 631

Psoriasis-Dormant Projects (Contd..22), H1 2015 632

Psoriasis-Discontinued Products, H1 2015 633

Psoriasis-Discontinued Products (Contd..1), H1 2015 634

Psoriasis-Discontinued Products (Contd..2), H1 2015 635

Psoriasis-Discontinued Products (Contd..3), H1 2015 636

Psoriasis-Discontinued Products (Contd..4), H1 2015 637

List of Figures

Number of Products under Development for Psoriasis, H1 2015 35

Number of Products under Development for Psoriasis-Comparative Analysis, H1 2015 36

Number of Products under Development by Companies, H1 2015 37

Number of Products under Investigation by Universities/Institutes, H1 2015 49

Comparative Analysis by Late Stage Development, H1 2015 50

Comparative Analysis by Clinical Stage Development, H1 2015 51

Comparative Analysis by Early Stage Products, H1 2015 52

Assessment by Monotherapy Products, H1 2015 203

Assessment by Combination Products, H1 2015 204

Number of Products by Top 10 Targets, H1 2015 205

Number of Products by Stage and Top 10 Targets, H1 2015 205

Number of Products by Top 10 Mechanism of Actions, H1 2015 211

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 211

Number of Products by Top 10 Routes of Administration, H1 2015 216

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 216

Number of Products by Top 10 Molecule Types, H1 2015 218

Number of Products by Stage and Top 10 Molecule Types, H1 2015 218

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4SC AG

AbGenomics International, Inc.

Acceleron Pharma, Inc.

Actelion Ltd

Addex Therapeutics Ltd

Advinus Therapeutics Ltd.

Ajinomoto Pharmaceuticals Co., Ltd.

AlbireoPharma

Allozyne, Inc.

Almirall, S.A.

AlphaMab Co., Ltd

Amgen Inc.

Anacor Pharmaceuticals, Inc.

Apexigen, Inc.

ApoPharma Inc.

Arena Pharmaceuticals, Inc.

Argos Therapeutics, Inc.

Arrien Pharmaceuticals, LLC

AuraSense Therapeutics, LLC

Avesthagen Limited

Avexxin AS

Basilea Pharmaceutica AG

BIOCAD

Biocon Limited

Bionomics Limited

Biotest AG

Biotie Therapies Corp.

Boehringer Ingelheim GmbH

Brickell Biotech, Inc.

Can-Fite BioPharma Ltd.

Celgene Corporation

Cellceutix Corporation

Celltrion, Inc.

ChemoCentryx, Inc.

ChironWells GmbH

Circassia Pharmaceuticals plc

Coherus BioSciences, Inc.

Compugen Ltd.

Convoy Therapeutics, Inc.

Covagen AG

Creabilis SA

Crescendo Biologics Limited

Delenex Therapeutics AG

Deltanoid Pharmaceuticals Inc.

Dermira Inc.

Effimune SAS

Eli Lilly and Company

Epirus Biopharmaceuticals, Inc.

Farmacija d.o.o. Tuzla

Fibrocell Science, Inc.

Foamix Pharmaceuticals Ltd.

Forward Pharma A/S

Gem Pharmaceuticals, LLC

Gene Signal International SA

Genentech, Inc.

Genor BioPharma Co., Ltd.

GlaxoSmithKline plc

GliaCure Inc.

GlycoMar Limited

Grupo Ferrer Internacional, S.A.

Hydra Biosciences, Inc.

Idera Pharmaceuticals, Inc.

Immune Response BioPharma, Inc.

Invion Limited

ISDIN

Johnson & Johnson

Kadmon Corporation, LLC

KaloBios Pharmaceuticals, Inc.

Kineta, Inc.

Kinex Pharmaceuticals, LLC

Kyowa Hakko Kirin Co., Ltd.

Lee's Pharmaceutical Holdings Limited

LegoChem Biosciences, Inc

LEO Pharma A/S

Lipidor AB

Lupin Limited

Lycera Corp.

Mabion SA

Maruho Co., Ltd.

MediGene AG

Merck KGaA

Mitsubishi Tanabe Pharma Corporation

NovaLead Pharma Pvt. Ltd.

Novartis AG

Oncobiologics, Inc.

Ono Pharmaceutical Co., Ltd.

OPKO Health, Inc.

Panacea Biotec Limited

Pfizer Inc.

Pharis Biotec GmbH

Pharmedartis GmbH

Phenex Pharmaceuticals AG

Pieris AG

PinCell srl

Promius Pharma, LLC

Protalix BioTherapeutics, Inc.

Prothena Corporation plc

Provectus Biopharmaceuticals, Inc.

PurGenesis Technologies Inc.

R-Tech Ueno, Ltd.

RedHill Biopharma Ltd.

RestorGenex Corporation

Rigel Pharmaceuticals, Inc.

Salix Pharmaceuticals Ltd.

Sandoz International GmbH

Sareum Holdings plc

Selvita SA

Sigmoid Pharma Limited

Soligenix, Inc.

Spherium Biomed S.L.

sterna biologicals Gmbh & Co KG

Sun Pharma Advanced Research Company Ltd.

Sun Pharmaceutical Industries Inc.

SWITCH Biotech LLC

Syntrix Biosystems, Inc.

Takeda Pharmaceutical Company Limited

Telormedix SA

TetraLogic Pharmaceuticals

Teva Pharmaceutical Industries Limited

Therapix Biosciences Ltd

Tolero Pharmaceuticals, Inc.

UCB S.A.

Uni-Bio Science Group Ltd.

Valeant Pharmaceuticals International, Inc.

Virobay Inc.

Vitae Pharmaceuticals, Inc.

Welichem Biotech Inc.

XBiotech USA, Inc.

XenoPort, Inc.

Ziarco Pharma Ltd

Psoriasis Therapeutic Products under Development, Key Players in Psoriasis Therapeutics, Psoriasis Pipeline Overview, Psoriasis Pipeline, Psoriasis Pipeline Assessment


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