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Rheumatoid Arthritis-Pipeline Review, H1 2015

Rheumatoid Arthritis-Pipeline Review, H1 2015


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Executive Summary

Rheumatoid Arthritis-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Rheumatoid Arthritis-Pipeline Review, H1 2015', provides an overview of the Rheumatoid Arthritis's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Rheumatoid Arthritis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Rheumatoid Arthritis and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Rheumatoid Arthritis

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Rheumatoid Arthritis and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Rheumatoid Arthritis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Rheumatoid Arthritis pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Rheumatoid Arthritis

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Rheumatoid Arthritis pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

Introduction 12

Rheumatoid Arthritis Overview 13

Therapeutics Development 14

Rheumatoid Arthritis-Therapeutics under Development by Companies 16

Rheumatoid Arthritis-Therapeutics under Investigation by Universities/Institutes 36

Rheumatoid Arthritis-Pipeline Products Glance 40

Rheumatoid Arthritis-Products under Development by Companies 44

Rheumatoid Arthritis-Products under Investigation by Universities/Institutes 72

Rheumatoid Arthritis-Companies Involved in Therapeutics Development 75

Rheumatoid Arthritis-Therapeutics Assessment 291

Drug Profiles 324

Rheumatoid Arthritis-Recent Pipeline Updates 892

Rheumatoid Arthritis-Dormant Projects 1027

Rheumatoid Arthritis-Discontinued Products 1063

Rheumatoid Arthritis-Product Development Milestones 1074

Appendix 1087

List of Tables

Number of Products under Development for Rheumatoid Arthritis, H1 2015 61

Number of Products under Development for Rheumatoid Arthritis-Comparative Analysis, H1 2015 62

Number of Products under Development by Companies, H1 2015 64

Number of Products under Development by Companies, H1 2015 (Contd..1) 65

Number of Products under Development by Companies, H1 2015 (Contd..2) 66

Number of Products under Development by Companies, H1 2015 (Contd..3) 67

Number of Products under Development by Companies, H1 2015 (Contd..4) 68

Number of Products under Development by Companies, H1 2015 (Contd..5) 69

Number of Products under Development by Companies, H1 2015 (Contd..6) 70

Number of Products under Development by Companies, H1 2015 (Contd..7) 71

Number of Products under Development by Companies, H1 2015 (Contd..8) 72

Number of Products under Development by Companies, H1 2015 (Contd..9) 73

Number of Products under Development by Companies, H1 2015 (Contd..10) 74

Number of Products under Development by Companies, H1 2015 (Contd..11) 75

Number of Products under Development by Companies, H1 2015 (Contd..12) 76

Number of Products under Development by Companies, H1 2015 (Contd..13) 77

Number of Products under Development by Companies, H1 2015 (Contd..14) 78

Number of Products under Development by Companies, H1 2015 (Contd..15) 79

Number of Products under Development by Companies, H1 2015 (Contd..16) 80

Number of Products under Development by Companies, H1 2015 (Contd..17) 81

Number of Products under Development by Companies, H1 2015 (Contd..18) 82

Number of Products under Investigation by Universities/Institutes, H1 2015 83

Number of Products under Investigation by Universities/Institutes, H1 2015 (Contd..1) 85

Number of Products under Investigation by Universities/Institutes, H1 2015 (Contd..2) 86

Comparative Analysis by Late Stage Development, H1 2015 87

Comparative Analysis by Clinical Stage Development, H1 2015 88

Comparative Analysis by Early Stage Development, H1 2015 89

Comparative Analysis by Unknown Stage Development, H1 2015 90

Products under Development by Companies, H1 2015 91

Products under Development by Companies, H1 2015 (Contd..1) 92

Products under Development by Companies, H1 2015 (Contd..2) 93

Products under Development by Companies, H1 2015 (Contd..3) 94

Products under Development by Companies, H1 2015 (Contd..4) 95

Products under Development by Companies, H1 2015 (Contd..5) 96

Products under Development by Companies, H1 2015 (Contd..6) 97

Products under Development by Companies, H1 2015 (Contd..7) 98

Products under Development by Companies, H1 2015 (Contd..8) 99

Products under Development by Companies, H1 2015 (Contd..9) 100

Products under Development by Companies, H1 2015 (Contd..10) 101

Products under Development by Companies, H1 2015 (Contd..11) 102

Products under Development by Companies, H1 2015 (Contd..12) 103

Products under Development by Companies, H1 2015 (Contd..13) 104

Products under Development by Companies, H1 2015 (Contd..14) 105

Products under Development by Companies, H1 2015 (Contd..15) 106

Products under Development by Companies, H1 2015 (Contd..16) 107

Products under Development by Companies, H1 2015 (Contd..17) 108

Products under Development by Companies, H1 2015 (Contd..18) 109

Products under Development by Companies, H1 2015 (Contd..19) 110

Products under Development by Companies, H1 2015 (Contd..20) 111

Products under Development by Companies, H1 2015 (Contd..21) 112

Products under Development by Companies, H1 2015 (Contd..22) 113

Products under Development by Companies, H1 2015 (Contd..23) 114

Products under Development by Companies, H1 2015 (Contd..24) 115

Products under Development by Companies, H1 2015 (Contd..25) 116

Products under Development by Companies, H1 2015 (Contd..26) 117

Products under Development by Companies, H1 2015 (Contd..27) 118

Products under Investigation by Universities/Institutes, H1 2015 119

Products under Investigation by Universities/Institutes, H1 2015 (Contd..1) 120

Products under Investigation by Universities/Institutes, H1 2015 (Contd..2) 121

Rheumatoid Arthritis-Pipeline by 3SBio Inc., H1 2015 122

Rheumatoid Arthritis-Pipeline by 4SC AG, H1 2015 123

Rheumatoid Arthritis-Pipeline by AB Science, H1 2015 124

Rheumatoid Arthritis-Pipeline by AB2 Bio Ltd., H1 2015 125

Rheumatoid Arthritis-Pipeline by AbbVie Inc., H1 2015 126

Rheumatoid Arthritis-Pipeline by Ablynx NV, H1 2015 127

Rheumatoid Arthritis-Pipeline by Acceleron Pharma, Inc., H1 2015 128

Rheumatoid Arthritis-Pipeline by Addex Therapeutics Ltd, H1 2015 129

Rheumatoid Arthritis-Pipeline by Advinus Therapeutics Ltd., H1 2015 130

Rheumatoid Arthritis-Pipeline by Aegera Therapeutics Inc., H1 2015 131

Rheumatoid Arthritis-Pipeline by Alder Biopharmaceuticals Inc., H1 2015 132

Rheumatoid Arthritis-Pipeline by AlphaMab Co., Ltd, H1 2015 133

Rheumatoid Arthritis-Pipeline by Amgen Inc., H1 2015 134

Rheumatoid Arthritis-Pipeline by Amura Holdings Limited, H1 2015 135

Rheumatoid Arthritis-Pipeline by Aprogen, Inc., H1 2015 136

Rheumatoid Arthritis-Pipeline by Araim Pharmaceuticals Inc., H1 2015 137

Rheumatoid Arthritis-Pipeline by Arena Pharmaceuticals, Inc., H1 2015 138

Rheumatoid Arthritis-Pipeline by arGentis Pharmaceuticals, LLC, H1 2015 139

Rheumatoid Arthritis-Pipeline by Arrien Pharmaceuticals, LLC, H1 2015 140

Rheumatoid Arthritis-Pipeline by Arthrogen BV, H1 2015 141

Rheumatoid Arthritis-Pipeline by Asahi Kasei Pharma Corp., H1 2015 142

Rheumatoid Arthritis-Pipeline by Aslan Pharmaceuticals Pte. Ltd., H1 2015 143

Rheumatoid Arthritis-Pipeline by Astellas Pharma Inc., H1 2015 144

Rheumatoid Arthritis-Pipeline by AstraZeneca Plc, H1 2015 145

Rheumatoid Arthritis-Pipeline by AuraSense Therapeutics, LLC, H1 2015 146

Rheumatoid Arthritis-Pipeline by Avesthagen Limited, H1 2015 147

Rheumatoid Arthritis-Pipeline by Avexxin AS, H1 2015 148

Rheumatoid Arthritis-Pipeline by Axxam SpA, H1 2015 149

Rheumatoid Arthritis-Pipeline by Baliopharm AG, H1 2015 150

Rheumatoid Arthritis-Pipeline by Bio-Cancer Treatment International Limited, H1 2015 151

Rheumatoid Arthritis-Pipeline by BIOCAD, H1 2015 152

Rheumatoid Arthritis-Pipeline by Biocon Limited, H1 2015 153

Rheumatoid Arthritis-Pipeline by Bioheart, Inc., H1 2015 154

Rheumatoid Arthritis-Pipeline by Biokine Therapeutics Ltd., H1 2015 155

Rheumatoid Arthritis-Pipeline by BioMarin Pharmaceutical Inc., H1 2015 156

Rheumatoid Arthritis-Pipeline by Bionomics Limited, H1 2015 157

Rheumatoid Arthritis-Pipeline by BioTherapeutics Inc., H1 2015 158

Rheumatoid Arthritis-Pipeline by Biotie Therapies Corp., H1 2015 159

Rheumatoid Arthritis-Pipeline by Boehringer Ingelheim GmbH, H1 2015 160

Rheumatoid Arthritis-Pipeline by Bone Medical Limited, H1 2015 161

Rheumatoid Arthritis-Pipeline by Boryung Pharmaceutical Co., Ltd., H1 2015 162

Rheumatoid Arthritis-Pipeline by Bristol-Myers Squibb Company, H1 2015 163

Rheumatoid Arthritis-Pipeline by Can-Fite BioPharma Ltd., H1 2015 164

Rheumatoid Arthritis-Pipeline by Cardax Pharmaceuticals, Inc., H1 2015 165

Rheumatoid Arthritis-Pipeline by CASI Pharmaceuticals Inc., H1 2015 166

Rheumatoid Arthritis-Pipeline by CEL-SCI Corporation, H1 2015 167

Rheumatoid Arthritis-Pipeline by Celgene Corporation, H1 2015 168

Rheumatoid Arthritis-Pipeline by Cellceutix Corporation, H1 2015 169

Rheumatoid Arthritis-Pipeline by Celltrion, Inc., H1 2015 170

Rheumatoid Arthritis-Pipeline by Cellworks Group, Inc., H1 2015 171

Rheumatoid Arthritis-Pipeline by ChemoCentryx, Inc., H1 2015 172

Rheumatoid Arthritis-Pipeline by Chipscreen Biosciences Ltd, H1 2015 173

Rheumatoid Arthritis-Pipeline by ChironWells GmbH, H1 2015 174

Rheumatoid Arthritis-Pipeline by Chong Kun Dang Pharmaceutical Corp., H1 2015 175

Rheumatoid Arthritis-Pipeline by Chugai Pharmaceutical Co., Ltd., H1 2015 176

Rheumatoid Arthritis-Pipeline by CLL Pharma, H1 2015 177

Rheumatoid Arthritis-Pipeline by Coherus BioSciences, Inc., H1 2015 178

Rheumatoid Arthritis-Pipeline by Compugen Ltd., H1 2015 179

Rheumatoid Arthritis-Pipeline by Creabilis SA, H1 2015 180

Rheumatoid Arthritis-Pipeline by CrystalGenomics, Inc., H1 2015 181

Rheumatoid Arthritis-Pipeline by Cyclacel Pharmaceuticals, Inc., H1 2015 182

Rheumatoid Arthritis-Pipeline by Daiichi Sankyo Company, Limited, H1 2015 183

Rheumatoid Arthritis-Pipeline by Dong-A Socio Group, H1 2015 184

Rheumatoid Arthritis-Pipeline by Effimune SAS, H1 2015 185

Rheumatoid Arthritis-Pipeline by Eisai Co., Ltd., H1 2015 186

Rheumatoid Arthritis-Pipeline by Eli Lilly and Company, H1 2015 187

Rheumatoid Arthritis-Pipeline by Emergent BioSolutions Inc., H1 2015 188

Rheumatoid Arthritis-Pipeline by Enceladus Pharmaceuticals BV, H1 2015 189

Rheumatoid Arthritis-Pipeline by Endocyte, Inc., H1 2015 190

Rheumatoid Arthritis-Pipeline by Ensemble Therapeutics Corporation, H1 2015 191

Rheumatoid Arthritis-Pipeline by Epirus Biopharmaceuticals, Inc., H1 2015 192

Rheumatoid Arthritis-Pipeline by F. Hoffmann-La Roche Ltd., H1 2015 193

Rheumatoid Arthritis-Pipeline by Farmacija d.o.o. Tuzla, H1 2015 194

Rheumatoid Arthritis-Pipeline by Five Prime Therapeutics, Inc., H1 2015 195

Rheumatoid Arthritis-Pipeline by Fountain Biopharma Inc., H1 2015 196

Rheumatoid Arthritis-Pipeline by Galapagos NV, H1 2015 197

Rheumatoid Arthritis-Pipeline by GeneFrontier Corporation, H1 2015 198

Rheumatoid Arthritis-Pipeline by Genentech, Inc., H1 2015 199

Rheumatoid Arthritis-Pipeline by Genor BioPharma Co., Ltd., H1 2015 200

Rheumatoid Arthritis-Pipeline by Genosco, H1 2015 201

Rheumatoid Arthritis-Pipeline by Gilead Sciences, Inc., H1 2015 202

Rheumatoid Arthritis-Pipeline by GlaxoSmithKline Plc, H1 2015 203

Rheumatoid Arthritis-Pipeline by Griffin Discoveries BV, H1 2015 204

Rheumatoid Arthritis-Pipeline by Handok Inc., H1 2015 205

Rheumatoid Arthritis-Pipeline by Hanmi Pharmaceuticals, Co. Ltd., H1 2015 206

Rheumatoid Arthritis-Pipeline by Hanwha Chemical Corporation, H1 2015 207

Rheumatoid Arthritis-Pipeline by Hospira, Inc., H1 2015 208

Rheumatoid Arthritis-Pipeline by Huabo Biopharm Co., Ltd., H1 2015 209

Rheumatoid Arthritis-Pipeline by Hutchison MediPharma Limited, H1 2015 210

Rheumatoid Arthritis-Pipeline by Idera Pharmaceuticals, Inc., H1 2015 211

Rheumatoid Arthritis-Pipeline by IMMD Inc., H1 2015 212

Rheumatoid Arthritis-Pipeline by Immune Response BioPharma, Inc., H1 2015 213

Rheumatoid Arthritis-Pipeline by ImmunoFrontier, Inc., H1 2015 214

Rheumatoid Arthritis-Pipeline by Inbiopro Solutions Pvt. Ltd., H1 2015 215

Rheumatoid Arthritis-Pipeline by Innate Pharma SA, H1 2015 216

Rheumatoid Arthritis-Pipeline by Innovent Biologics, Inc., H1 2015 217

Rheumatoid Arthritis-Pipeline by Invion Limited, H1 2015 218

Rheumatoid Arthritis-Pipeline by InvivoGen Therapeutics, H1 2015 219

Rheumatoid Arthritis-Pipeline by Jiangsu Hengrui Medicine Co., Ltd., H1 2015 220

Rheumatoid Arthritis-Pipeline by Johnson & Johnson, H1 2015 221

Rheumatoid Arthritis-Pipeline by Kadmon Corporation, LLC, H1 2015 222

Rheumatoid Arthritis-Pipeline by KAHR medical Ltd., H1 2015 223

Rheumatoid Arthritis-Pipeline by Kineta, Inc., H1 2015 224

Rheumatoid Arthritis-Pipeline by Lead Pharma Holding B.V., H1 2015 225

Rheumatoid Arthritis-Pipeline by LG Life Sciences, Ltd., H1 2015 226

Rheumatoid Arthritis-Pipeline by Lupin Limited, H1 2015 227

Rheumatoid Arthritis-Pipeline by Lycera Corp., H1 2015 228

Rheumatoid Arthritis-Pipeline by Mabion SA, H1 2015 229

Rheumatoid Arthritis-Pipeline by MacroGenics, Inc., H1 2015 230

Rheumatoid Arthritis-Pipeline by MaimoniDex RA Ltd., H1 2015 231

Rheumatoid Arthritis-Pipeline by Mebiopharm Co., Ltd., H1 2015 232

Rheumatoid Arthritis-Pipeline by MedAnnex Ltd, H1 2015 233

Rheumatoid Arthritis-Pipeline by MediGene AG, H1 2015 234

Rheumatoid Arthritis-Pipeline by MedImmune, LLC, H1 2015 235

Rheumatoid Arthritis-Pipeline by Merck & Co., Inc., H1 2015 236

Rheumatoid Arthritis-Pipeline by Mertiva AB, H1 2015 237

Rheumatoid Arthritis-Pipeline by Mesoblast Limited, H1 2015 238

Rheumatoid Arthritis-Pipeline by MetrioPharm AG, H1 2015 239

Rheumatoid Arthritis-Pipeline by Mitsubishi Tanabe Pharma Corporation, H1 2015 240

Rheumatoid Arthritis-Pipeline by Modern Biosciences Plc, H1 2015 241

Rheumatoid Arthritis-Pipeline by ModiQuest B.V., H1 2015 242

Rheumatoid Arthritis-Pipeline by Momenta Pharmaceuticals, Inc., H1 2015 243

Rheumatoid Arthritis-Pipeline by Morphotek, Inc., H1 2015 244

Rheumatoid Arthritis-Pipeline by Mycenax Biotech Inc., H1 2015 245

Rheumatoid Arthritis-Pipeline by Myos Corporation, H1 2015 246

Rheumatoid Arthritis-Pipeline by Myungmoon pharmaceutical Co.,Ltd., H1 2015 247

Rheumatoid Arthritis-Pipeline by Navigen Pharmaceuticals, Inc., H1 2015 248

Rheumatoid Arthritis-Pipeline by Neovacs SA, H1 2015 249

Rheumatoid Arthritis-Pipeline by Nichi-Iko Pharmaceutical Co., Ltd., H1 2015 250

Rheumatoid Arthritis-Pipeline by Nimbus Therapeutics, LLC, H1 2015 251

Rheumatoid Arthritis-Pipeline by Novartis AG, H1 2015 252

Rheumatoid Arthritis-Pipeline by NovImmune SA, H1 2015 253

Rheumatoid Arthritis-Pipeline by Nuvo Research Inc., H1 2015 254

Rheumatoid Arthritis-Pipeline by Omeros Corporation, H1 2015 255

Rheumatoid Arthritis-Pipeline by Oncobiologics, Inc., H1 2015 256

Rheumatoid Arthritis-Pipeline by OncoImmune, Inc., H1 2015 257

Rheumatoid Arthritis-Pipeline by Ono Pharmaceutical Co., Ltd., H1 2015 258

Rheumatoid Arthritis-Pipeline by Onyx Pharmaceuticals, Inc., H1 2015 259

Rheumatoid Arthritis-Pipeline by OPKO Health, Inc., H1 2015 260

Rheumatoid Arthritis-Pipeline by Opsona Therapeutics Limited, H1 2015 261

Rheumatoid Arthritis-Pipeline by Orchid Chemicals & Pharmaceuticals Ltd, H1 2015 262

Rheumatoid Arthritis-Pipeline by Oscotec Inc., H1 2015 263

Rheumatoid Arthritis-Pipeline by Padlock Therapeutics, Inc., H1 2015 264

Rheumatoid Arthritis-Pipeline by Panacea Biotec Limited, H1 2015 265

Rheumatoid Arthritis-Pipeline by Paras Biopharmaceuticals Finland Oy, H1 2015 266

Rheumatoid Arthritis-Pipeline by Peptinnovate Limited, H1 2015 267

Rheumatoid Arthritis-Pipeline by Peptinov SAS, H1 2015 268

Rheumatoid Arthritis-Pipeline by Pfenex Inc., H1 2015 269

Rheumatoid Arthritis-Pipeline by Pfizer Inc., H1 2015 270

Rheumatoid Arthritis-Pipeline by Pharmacyclics, Inc., H1 2015 271

Rheumatoid Arthritis-Pipeline by PharmaIN Corporation, H1 2015 272

Rheumatoid Arthritis-Pipeline by Pharmedartis GmbH, H1 2015 273

Rheumatoid Arthritis-Pipeline by Phenex Pharmaceuticals AG, H1 2015 274

Rheumatoid Arthritis-Pipeline by Philogen S.p.A., H1 2015 275

Rheumatoid Arthritis-Pipeline by Phylogica Limited, H1 2015 276

Rheumatoid Arthritis-Pipeline by Principia Biopharma Inc., H1 2015 277

Rheumatoid Arthritis-Pipeline by Progenra, Inc., H1 2015 278

Rheumatoid Arthritis-Pipeline by ProNoxis AB, H1 2015 279

Rheumatoid Arthritis-Pipeline by ProtAb Ltd, H1 2015 280

Rheumatoid Arthritis-Pipeline by Protalex, Inc., H1 2015 281

Rheumatoid Arthritis-Pipeline by Protalix BioTherapeutics, Inc., H1 2015 282

Rheumatoid Arthritis-Pipeline by Provid Pharmaceuticals, Inc., H1 2015 283

Rheumatoid Arthritis-Pipeline by PurGenesis Technologies Inc., H1 2015 284

Rheumatoid Arthritis-Pipeline by Qu Biologics Inc., H1 2015 285

Rheumatoid Arthritis-Pipeline by R-Pharm, H1 2015 286

Rheumatoid Arthritis-Pipeline by Re-Pharm Limited, H1 2015 287

Rheumatoid Arthritis-Pipeline by Reata Pharmaceuticals, Inc., H1 2015 288

Rheumatoid Arthritis-Pipeline by Recoly N.V., H1 2015 289

Rheumatoid Arthritis-Pipeline by RedHill Biopharma Ltd., H1 2015 290

Rheumatoid Arthritis-Pipeline by Redx Pharma Plc, H1 2015 291

Rheumatoid Arthritis-Pipeline by Regeneron Pharmaceuticals, Inc., H1 2015 292

Rheumatoid Arthritis-Pipeline by Reliance Life Sciences Pvt. Ltd., H1 2015 293

Rheumatoid Arthritis-Pipeline by ReveraGen BioPharma, Inc., H1 2015 294

Rheumatoid Arthritis-Pipeline by Rhizen Pharmaceuticals SA, H1 2015 295

Rheumatoid Arthritis-Pipeline by Richter Gedeon Nyrt., H1 2015 296

Rheumatoid Arthritis-Pipeline by Rottapharm SpA, H1 2015 297

Rheumatoid Arthritis-Pipeline by Salix Pharmaceuticals Ltd., H1 2015 298

Rheumatoid Arthritis-Pipeline by Sandoz International GmbH, H1 2015 299

Rheumatoid Arthritis-Pipeline by Sareum Holdings Plc, H1 2015 300

Rheumatoid Arthritis-Pipeline by SBI Biotech Co., Ltd., H1 2015 301

Rheumatoid Arthritis-Pipeline by Selvita SA, H1 2015 302

Rheumatoid Arthritis-Pipeline by Shanghai Henlius Biotech Co., Ltd., H1 2015 303

Rheumatoid Arthritis-Pipeline by Shanghai Pharmaceutical Co., Ltd., H1 2015 304

Rheumatoid Arthritis-Pipeline by Spectrum Pharmaceuticals, Inc., H1 2015 305

Rheumatoid Arthritis-Pipeline by Sun Pharmaceutical Industries Limited, H1 2015 306

Rheumatoid Arthritis-Pipeline by Swedish Orphan Biovitrum AB, H1 2015 307

Rheumatoid Arthritis-Pipeline by Synovo GmbH, H1 2015 308

Rheumatoid Arthritis-Pipeline by Syntrix Biosystems, Inc., H1 2015 309

Rheumatoid Arthritis-Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 310

Rheumatoid Arthritis-Pipeline by TechnoPhage SA, H1 2015 311

Rheumatoid Arthritis-Pipeline by Teijin Pharma Limited, H1 2015 312

Rheumatoid Arthritis-Pipeline by Teva Pharmaceutical Industries Limited, H1 2015 313

Rheumatoid Arthritis-Pipeline by TheraMAB, H1 2015 314

Rheumatoid Arthritis-Pipeline by Therapeutic Proteins International, LLC, H1 2015 315

Rheumatoid Arthritis-Pipeline by TiGenix NV, H1 2015 316

Rheumatoid Arthritis-Pipeline by Toleranzia AB, H1 2015 317

Rheumatoid Arthritis-Pipeline by Toyama Chemical Co., Ltd., H1 2015 318

Rheumatoid Arthritis-Pipeline by TSH Biopharm Corporation Limited, H1 2015 319

Rheumatoid Arthritis-Pipeline by TxCell SA, H1 2015 320

Rheumatoid Arthritis-Pipeline by UCB S.A., H1 2015 321

Rheumatoid Arthritis-Pipeline by ugichem GmbH, H1 2015 322

Rheumatoid Arthritis-Pipeline by UNIZYME Laboratories A/S, H1 2015 323

Rheumatoid Arthritis-Pipeline by Vaccinex, Inc., H1 2015 324

Rheumatoid Arthritis-Pipeline by Vertex Pharmaceuticals Incorporated, H1 2015 325

Rheumatoid Arthritis-Pipeline by Vichem Chemie Research Ltd., H1 2015 326

Rheumatoid Arthritis-Pipeline by Vicore Pharma AB, H1 2015 327

Rheumatoid Arthritis-Pipeline by Vida Therapeutics Inc., H1 2015 328

Rheumatoid Arthritis-Pipeline by Vivia Biotech, S.L., H1 2015 329

Rheumatoid Arthritis-Pipeline by XBiotech USA, Inc., H1 2015 330

Rheumatoid Arthritis-Pipeline by Xencor, Inc., H1 2015 331

Rheumatoid Arthritis-Pipeline by Xenexus Pharmaceuticals Pty. Ltd., H1 2015 332

Rheumatoid Arthritis-Pipeline by XTL Biopharmaceuticals Ltd., H1 2015 333

Rheumatoid Arthritis-Pipeline by Yuhan Corporation, H1 2015 334

Rheumatoid Arthritis-Pipeline by Yungjin Pharm Ind. Co., Ltd., H1 2015 335

Rheumatoid Arthritis-Pipeline by Zydus Cadila Healthcare Limited, H1 2015 336

Rheumatoid Arthritis-Pipeline by Zynerba Pharmaceuticals, Inc., H1 2015 337

Assessment by Monotherapy Products, H1 2015 338

Assessment by Combination Products, H1 2015 339

Number of Products by Stage and Target, H1 2015 341

Number of Products by Stage and Mechanism of Action, H1 2015 357

Number of Products by Stage and Route of Administration, H1 2015 368

Number of Products by Stage and Molecule Type, H1 2015 370

Rheumatoid Arthritis Therapeutics-Recent Pipeline Updates, H1 2015 939

Rheumatoid Arthritis-Dormant Projects, H1 2015 1074

Rheumatoid Arthritis-Dormant Projects (Contd..1), H1 2015 1075

Rheumatoid Arthritis-Dormant Projects (Contd..2), H1 2015 1076

Rheumatoid Arthritis-Dormant Projects (Contd..3), H1 2015 1077

Rheumatoid Arthritis-Dormant Projects (Contd..4), H1 2015 1078

Rheumatoid Arthritis-Dormant Projects (Contd..5), H1 2015 1079

Rheumatoid Arthritis-Dormant Projects (Contd..6), H1 2015 1080

Rheumatoid Arthritis-Dormant Projects (Contd..7), H1 2015 1081

Rheumatoid Arthritis-Dormant Projects (Contd..8), H1 2015 1082

Rheumatoid Arthritis-Dormant Projects (Contd..9), H1 2015 1083

Rheumatoid Arthritis-Dormant Projects (Contd..10), H1 2015 1084

Rheumatoid Arthritis-Dormant Projects (Contd..11), H1 2015 1085

Rheumatoid Arthritis-Dormant Projects (Contd..12), H1 2015 1086

Rheumatoid Arthritis-Dormant Projects (Contd..13), H1 2015 1087

Rheumatoid Arthritis-Dormant Projects (Contd..14), H1 2015 1088

Rheumatoid Arthritis-Dormant Projects (Contd..15), H1 2015 1089

Rheumatoid Arthritis-Dormant Projects (Contd..16), H1 2015 1090

Rheumatoid Arthritis-Dormant Projects (Contd..17), H1 2015 1091

Rheumatoid Arthritis-Dormant Projects (Contd..18), H1 2015 1092

Rheumatoid Arthritis-Dormant Projects (Contd..19), H1 2015 1093

Rheumatoid Arthritis-Dormant Projects (Contd..20), H1 2015 1094

Rheumatoid Arthritis-Dormant Projects (Contd..21), H1 2015 1095

Rheumatoid Arthritis-Dormant Projects (Contd..22), H1 2015 1096

Rheumatoid Arthritis-Dormant Projects (Contd..23), H1 2015 1097

Rheumatoid Arthritis-Dormant Projects (Contd..24), H1 2015 1098

Rheumatoid Arthritis-Dormant Projects (Contd..25), H1 2015 1099

Rheumatoid Arthritis-Dormant Projects (Contd..26), H1 2015 1100

Rheumatoid Arthritis-Dormant Projects (Contd..27), H1 2015 1101

Rheumatoid Arthritis-Dormant Projects (Contd..28), H1 2015 1102

Rheumatoid Arthritis-Dormant Projects (Contd..29), H1 2015 1103

Rheumatoid Arthritis-Dormant Projects (Contd..30), H1 2015 1104

Rheumatoid Arthritis-Dormant Projects (Contd..31), H1 2015 1105

Rheumatoid Arthritis-Dormant Projects (Contd..32), H1 2015 1106

Rheumatoid Arthritis-Dormant Projects (Contd..33), H1 2015 1107

Rheumatoid Arthritis-Dormant Projects (Contd..34), H1 2015 1108

Rheumatoid Arthritis-Dormant Projects (Contd..35), H1 2015 1109

Rheumatoid Arthritis-Discontinued Products, H1 2015 1110

Rheumatoid Arthritis-Discontinued Products (Contd..1), H1 2015 1111

Rheumatoid Arthritis-Discontinued Products (Contd..2), H1 2015 1112

Rheumatoid Arthritis-Discontinued Products (Contd..3), H1 2015 1113

Rheumatoid Arthritis-Discontinued Products (Contd..4), H1 2015 1114

Rheumatoid Arthritis-Discontinued Products (Contd..5), H1 2015 1115

Rheumatoid Arthritis-Discontinued Products (Contd..6), H1 2015 1116

Rheumatoid Arthritis-Discontinued Products (Contd..7), H1 2015 1117

Rheumatoid Arthritis-Discontinued Products (Contd..8), H1 2015 1118

Rheumatoid Arthritis-Discontinued Products (Contd..9), H1 2015 1119

Rheumatoid Arthritis-Discontinued Products (Contd..10), H1 2015 1120

List of Figures

Number of Products under Development for Rheumatoid Arthritis, H1 2015 61

Number of Products under Development for Rheumatoid Arthritis-Comparative Analysis, H1 2015 62

Number of Products under Development by Companies, H1 2015 63

Number of Products under Investigation by Universities/Institutes, H1 2015 83

Comparative Analysis by Late Stage Development, H1 2015 87

Comparative Analysis by Clinical Stage Development, H1 2015 88

Comparative Analysis by Early Stage Products, H1 2015 89

Assessment by Monotherapy Products, H1 2015 338

Assessment by Combination Products, H1 2015 339

Number of Products by Top 10 Targets, H1 2015 340

Number of Products by Stage and Top 10 Targets, H1 2015 340

Number of Products by Top 10 Mechanism of Actions, H1 2015 356

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 356

Number of Products by Top 10 Routes of Administration, H1 2015 367

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 367

Number of Products by Top 10 Molecule Types, H1 2015 369

Number of Products by Stage and Top 10 Molecule Types, H1 2015 369

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Alder Biopharmaceuticals Inc.

AlphaMab Co., Ltd

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Amura Holdings Limited

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Araim Pharmaceuticals Inc.

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Avesthagen Limited

Avexxin AS

Axxam SpA

Baliopharm AG

Bio-Cancer Treatment International Limited

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Biocon Limited

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Bionomics Limited

BioTherapeutics Inc.

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Bristol-Myers Squibb Company

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CASI Pharmaceuticals Inc.

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Cellworks Group, Inc.

ChemoCentryx, Inc.

Chipscreen Biosciences Ltd

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CLL Pharma

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Compugen Ltd.

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Genor BioPharma Co., Ltd.

Genosco

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Handok Inc.

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Immune Response BioPharma, Inc.

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Invion Limited

InvivoGen Therapeutics

Jiangsu Hengrui Medicine Co., Ltd.

Johnson & Johnson

Kadmon Corporation, LLC

KAHR medical Ltd.

Kineta, Inc.

Lead Pharma Holding B.V.

LG Life Sciences, Ltd.

Lupin Limited

Lycera Corp.

Mabion SA

MacroGenics, Inc.

MaimoniDex RA Ltd.

Mebiopharm Co., Ltd.

MedAnnex Ltd

MediGene AG

MedImmune, LLC

Merck & Co., Inc.

Mertiva AB

Mesoblast Limited

MetrioPharm AG

Mitsubishi Tanabe Pharma Corporation

Modern Biosciences Plc

ModiQuest B.V.

Momenta Pharmaceuticals, Inc.

Morphotek, Inc.

Mycenax Biotech Inc.

Myos Corporation

Myungmoon pharmaceutical Co.,Ltd.

Navigen Pharmaceuticals, Inc.

Neovacs SA

Nichi-Iko Pharmaceutical Co., Ltd.

Nimbus Therapeutics, LLC

Novartis AG

NovImmune SA

Nuvo Research Inc.

Omeros Corporation

Oncobiologics, Inc.

OncoImmune, Inc.

Ono Pharmaceutical Co., Ltd.

Onyx Pharmaceuticals, Inc.

OPKO Health, Inc.

Opsona Therapeutics Limited

Orchid Chemicals & Pharmaceuticals Ltd

Oscotec Inc.

Padlock Therapeutics, Inc.

Panacea Biotec Limited

Paras Biopharmaceuticals Finland Oy

Peptinnovate Limited

Peptinov SAS

Pfenex Inc.

Pfizer Inc.

Pharmacyclics, Inc.

PharmaIN Corporation

Pharmedartis GmbH

Phenex Pharmaceuticals AG

Philogen S.p.A.

Phylogica Limited

Principia Biopharma Inc.

Progenra, Inc.

ProNoxis AB

ProtAb Ltd

Protalex, Inc.

Protalix BioTherapeutics, Inc.

Provid Pharmaceuticals, Inc.

PurGenesis Technologies Inc.

Qu Biologics Inc.

R-Pharm

Re-Pharm Limited

Reata Pharmaceuticals, Inc.

Recoly N.V.

RedHill Biopharma Ltd.

Redx Pharma Plc

Regeneron Pharmaceuticals, Inc.

Reliance Life Sciences Pvt. Ltd.

ReveraGen BioPharma, Inc.

Rhizen Pharmaceuticals SA

Richter Gedeon Nyrt.

Rottapharm SpA

Salix Pharmaceuticals Ltd.

Sandoz International GmbH

Sareum Holdings Plc

SBI Biotech Co., Ltd.

Selvita SA

Shanghai Henlius Biotech Co., Ltd.

Shanghai Pharmaceutical Co., Ltd.

Spectrum Pharmaceuticals, Inc.

Sun Pharmaceutical Industries Limited

Swedish Orphan Biovitrum AB

Synovo GmbH

Syntrix Biosystems, Inc.

Takeda Pharmaceutical Company Limited

TechnoPhage SA

Teijin Pharma Limited

Teva Pharmaceutical Industries Limited

TheraMAB

Therapeutic Proteins International, LLC

TiGenix NV

Toleranzia AB

Toyama Chemical Co., Ltd.

TSH Biopharm Corporation Limited

TxCell SA

UCB S.A.

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UNIZYME Laboratories A/S

Vaccinex, Inc.

Vertex Pharmaceuticals Incorporated

Vichem Chemie Research Ltd.

Vicore Pharma AB

Vida Therapeutics Inc.

Vivia Biotech, S.L.

XBiotech USA, Inc.

Xencor, Inc.

Xenexus Pharmaceuticals Pty. Ltd.

XTL Biopharmaceuticals Ltd.

Yuhan Corporation

Yungjin Pharm Ind. Co., Ltd.

Zydus Cadila Healthcare Limited

Zynerba Pharmaceuticals, Inc.

Rheumatoid Arthritis Therapeutic Products under Development, Key Players in Rheumatoid Arthritis Therapeutics, Rheumatoid Arthritis Pipeline Overview, Rheumatoid Arthritis Pipeline, Rheumatoid Arthritis Pipeline Assessment


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