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Sleep Apnea-Pipeline Review, H1 2015

Sleep Apnea-Pipeline Review, H1 2015


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Executive Summary

Sleep Apnea-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Sleep Apnea-Pipeline Review, H1 2015', provides an overview of the Sleep Apnea's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Sleep Apnea, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Sleep Apnea and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Sleep Apnea

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Sleep Apnea and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Sleep Apnea products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Sleep Apnea pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Sleep Apnea

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Sleep Apnea pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Sleep Apnea Overview 6

Therapeutics Development 7

Pipeline Products for Sleep Apnea-Overview 7

Pipeline Products for Sleep Apnea-Comparative Analysis 8

Sleep Apnea-Therapeutics under Development by Companies 9

Sleep Apnea-Pipeline Products Glance 10

Clinical Stage Products 10

Early Stage Products 11

Sleep Apnea-Products under Development by Companies 12

Sleep Apnea-Companies Involved in Therapeutics Development 13

Cortex Pharmaceuticals, Inc. 13

Galleon Pharmaceuticals 14

Rottapharm SpA 15

SK Biopharmaceuticals Co., Ltd. 16

Sleep Apnea-Therapeutics Assessment 17

Assessment by Monotherapy Products 17

Assessment by Target 18

Assessment by Mechanism of Action 20

Assessment by Route of Administration 22

Assessment by Molecule Type 24

Drug Profiles 25

CX-1739-Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

CX-2007-Drug Profile 27

Product Description 27

Mechanism of Action 27

R&D Progress 27

CX-2076-Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

dexloxiglumide-Drug Profile 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

doxapram hydrochloride-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

dronabinol-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

GAL-021-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

GAL-160-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

GAL-160 Backups-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

itriglumide-Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

SKL-N05-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

Sleep Apnea-Recent Pipeline Updates 38

Sleep Apnea-Dormant Projects 42

Sleep Apnea-Discontinued Products 43

Sleep Apnea-Product Development Milestones 44

Featured News & Press Releases 44

Sep 02, 2014: Galleon Pharmaceuticals Announces Publication of Proof-of-Concept Clinical Studies for GAL-021, Projected Use for the Emerging Perioperative Sleep Apnea Epidemic 44

Jan 06, 2014: Galleon Scientists Win Prestigious Research Awards for First-in-Class Treatment of Emerging Perioperative Sleep Apnea Epidemic 45

Apr 11, 2013: Galleon Pharma's GAL-021 Demonstrates Positive Results In Clinical Proof-of-Concept Study 45

Mar 13, 2012: Cortex Reports Issuance Of Patents For Next Generation Of Ampakine Compounds 46

Mar 13, 2012: Cortex Obtains Patents For Next Generation Of Ampakine Compounds 47

Apr 26, 2011: Cortex Receives US Patent For Lead AMPAKINE Molecule CX1739 47

Feb 02, 2011: Cortex's Ampakine CX1739 Improves Respiratory Parameters In Obstructive Sleep Apnea Patients 48

Appendix 50

Methodology 50

Coverage 50

Secondary Research 50

Primary Research 50

Expert Panel Validation 50

Contact Us 50

Disclaimer 51

List of Tables

Number of Products under Development for Sleep Apnea, H1 2015 7

Number of Products under Development for Sleep Apnea-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Comparative Analysis by Early Stage Development, H1 2015 11

Products under Development by Companies, H1 2015 12

Sleep Apnea-Pipeline by Cortex Pharmaceuticals, Inc., H1 2015 13

Sleep Apnea-Pipeline by Galleon Pharmaceuticals, H1 2015 14

Sleep Apnea-Pipeline by Rottapharm SpA, H1 2015 15

Sleep Apnea-Pipeline by SK Biopharmaceuticals Co., Ltd., H1 2015 16

Assessment by Monotherapy Products, H1 2015 17

Number of Products by Stage and Target, H1 2015 19

Number of Products by Stage and Mechanism of Action, H1 2015 21

Number of Products by Stage and Route of Administration, H1 2015 23

Number of Products by Stage and Molecule Type, H1 2015 24

Sleep Apnea Therapeutics-Recent Pipeline Updates, H1 2015 38

Sleep Apnea-Dormant Projects, H1 2015 42

Sleep Apnea-Discontinued Products, H1 2015 43

List of Figures

Number of Products under Development for Sleep Apnea, H1 2015 7

Number of Products under Development for Sleep Apnea-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Comparative Analysis by Early Stage Products, H1 2015 11

Assessment by Monotherapy Products, H1 2015 17

Number of Products by Top 10 Targets, H1 2015 18

Number of Products by Stage and Top 10 Targets, H1 2015 18

Number of Products by Top 10 Mechanism of Actions, H1 2015 20

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 20

Number of Products by Top 10 Routes of Administration, H1 2015 22

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 22

Number of Products by Stage and Top 10 Molecule Types, H1 2015 24

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Cortex Pharmaceuticals, Inc.

Galleon Pharmaceuticals

Rottapharm SpA

SK Biopharmaceuticals Co., Ltd.

Sleep Apnea Therapeutic Products under Development, Key Players in Sleep Apnea Therapeutics, Sleep Apnea Pipeline Overview, Sleep Apnea Pipeline, Sleep Apnea Pipeline Assessment


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