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Xerostomia-Pipeline Review, H1 2015

Xerostomia-Pipeline Review, H1 2015


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Executive Summary

Xerostomia-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Xerostomia-Pipeline Review, H1 2015', provides an overview of the Xerostomia's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Xerostomia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Xerostomia and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Xerostomia

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Xerostomia and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Xerostomia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Xerostomia pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Xerostomia

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Xerostomia pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Xerostomia Overview 6

Therapeutics Development 7

Pipeline Products for Xerostomia-Overview 7

Pipeline Products for Xerostomia-Comparative Analysis 8

Xerostomia-Therapeutics under Development by Companies 9

Xerostomia-Therapeutics under Investigation by Universities/Institutes 10

Xerostomia-Pipeline Products Glance 11

Clinical Stage Products 11

Early Stage Products 12

Xerostomia-Products under Development by Companies 13

Xerostomia-Products under Investigation by Universities/Institutes 14

Xerostomia-Companies Involved in Therapeutics Development 15

Acacia Pharma Ltd. 15

Hadasit Medical Research Services & Development Ltd 16

Kadmon Corporation, LLC 17

Parion Sciences, Inc. 18

Xerostomia-Therapeutics Assessment 19

Assessment by Monotherapy Products 19

Assessment by Target 20

Assessment by Mechanism of Action 22

Assessment by Route of Administration 24

Assessment by Molecule Type 26

Drug Profiles 28

APD-515-Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

Gene Therapy to Activate Aquaporin-1 for Xerostomia-Drug Profile 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

Gene Therapy to Activate Aquaporin-1 for Xerostomia-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

HYPER-IL-6-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

P-552-Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

Xerostomia-Recent Pipeline Updates 35

Xerostomia-Dormant Projects 36

Xerostomia-Product Development Milestones 37

Featured News & Press Releases 37

Oct 15, 2013: Acacia Pharma Announces Positive Phase II Results With APD515 for Xerostomia in Advanced Cancer 37

Jul 25, 2011: Acacia Pharma Initiates Phase II Clinical Trial With APD515 For Xerostomia 38

Feb 07, 2011: Acacia Pharma Completes Phase I Clinical Trial With APD515 For Xerostomia 38

Jan 06, 2011: Acacia Pharma Starts Clinical Trial With APD515 In Xerostomia 39

Appendix 40

Methodology 40

Coverage 40

Secondary Research 40

Primary Research 40

Expert Panel Validation 40

Contact Us 40

Disclaimer 41

List of Tables

Number of Products under Development for Xerostomia, H1 2015 7

Number of Products under Development for Xerostomia-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Number of Products under Investigation by Universities/Institutes, H1 2015 10

Comparative Analysis by Clinical Stage Development, H1 2015 11

Comparative Analysis by Early Stage Development, H1 2015 12

Products under Development by Companies, H1 2015 13

Products under Investigation by Universities/Institutes, H1 2015 14

Xerostomia-Pipeline by Acacia Pharma Ltd., H1 2015 15

Xerostomia-Pipeline by Hadasit Medical Research Services & Development Ltd, H1 2015 16

Xerostomia-Pipeline by Kadmon Corporation, LLC, H1 2015 17

Xerostomia-Pipeline by Parion Sciences, Inc., H1 2015 18

Assessment by Monotherapy Products, H1 2015 19

Number of Products by Stage and Target, H1 2015 21

Number of Products by Stage and Mechanism of Action, H1 2015 23

Number of Products by Stage and Route of Administration, H1 2015 25

Number of Products by Stage and Molecule Type, H1 2015 27

Xerostomia Therapeutics-Recent Pipeline Updates, H1 2015 35

Xerostomia-Dormant Projects, H1 2015 36

List of Figures

Number of Products under Development for Xerostomia, H1 2015 7

Number of Products under Development for Xerostomia-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 11

Assessment by Monotherapy Products, H1 2015 19

Number of Products by Top 10 Targets, H1 2015 20

Number of Products by Stage and Top 10 Targets, H1 2015 21

Number of Products by Top 10 Mechanism of Actions, H1 2015 22

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 23

Number of Products by Top 10 Routes of Administration, H1 2015 24

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 25

Number of Products by Top 10 Molecule Types, H1 2015 26

Number of Products by Stage and Top 10 Molecule Types, H1 2015 27

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Acacia Pharma Ltd.

Hadasit Medical Research Services & Development Ltd

Kadmon Corporation, LLC

Parion Sciences, Inc.

Xerostomia Therapeutic Products under Development, Key Players in Xerostomia Therapeutics, Xerostomia Pipeline Overview, Xerostomia Pipeline, Xerostomia Pipeline Assessment


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