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MicroRNA (miRNAs) Market: Current Analysis and Forecast (2021-2027)

Region:Global

Author(s):

Product Code:UMHE21302

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Published on

July 2021

Total pages

127

Table of Content

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About the Report

About the Report

At present, there are over 2000 MicroRNA (miRNAs) discovered in humans that helps in the regulation of gene expression. Most of the human disease occurs due to genetic changes, hence miRNA is considered to be an important part of clinical diagnostics and therapeutic agents. MicroRNA (miRNA)-based therapeutics can be divided into miRNA mimics and inhibitors of miRNAs (antimiRs). For instance, miR-34a is a miRNA mimic that targets the BCL2, MET, MYC, CDK6, and other genes for the treatment of solid tumors (e.g., lung, liver, colon, brain, prostate, pancreatic, bladder, and cervical), Myeloma, and B cell lymphoma.

The demand for miRNA is mainly increasing on account of the emerging microRNA (miRNA) tools for disease-associated applications, the high role of miRNA in the target identification and prediction, and the high adoption of miRNA as a potential biomarker. Moreover, the role of miRNA in the diagnosis and treatment of various chronic diseases such as cancer, neurological disease, liver disease, metabolic diseases, and chronic heart diseases is also propelling the market growth. The overexpressed miRNA in certain diseases is known as oncogenes while the under-expressed miRNA in certain diseases is known as tumor suppressor miRNA. For instance, miRNA-212 functions as a tumor suppressor in colorectal carcinoma through targeting SOX4.

However, some of the restraints in the market include the safety and toxicity issues of miRNA in the treatment of certain diseases. Based on Products, the market is fragmented into Instruments and Consumables. The instruments segment holds the largest share in 2020 and is expected to register the highest CAGR in the upcoming period. In the recent few years, there is an increase in the number of miRNA-based clinical trials coupled with the rising incidents of chronic diseases. The various instruments are required in the completion of miRNA-based clinical trials such as TransmiR, DIANA-mirGen v.3 which is propelling the segment growth in the market.
 
Based on Services, the market is fragmented into Service Type and Specimen. The Service Type segment holds the largest share in 2020 and is expected to register the highest CAGR in the upcoming period owing to the rising strategic collaboration between companies for providing microRNA profiling services. For instance, LC Sciences announced its strategic collaboration with DNAVision to increase accessibility to its custom microRNA profiling service and enhance both its customer and technical service to researchers in Europe.

Based on Applications, the market is fragmented into Cancer, Infectious Diseases, Immunological Disorders, Cardiovascular Disease, Neurological Disease, and Others. The Cancer segment holds the largest share in 2020 and is expected to register the highest CAGR in the upcoming period owing to the rising clinical trials of miRNA in the treatment of cancer coupled with the rising prevalence of cancer cases. As per the International Agency for Research on Cancer (IARC) 1 in 5 people develop cancer during their lifetime globally and 1 in 8 men and 1 in 11 women die from cancer.

Based on End-user, the market is fragmented into Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, and Other end-users. The Biotechnology & Pharmaceutical Companies segment holds the largest share in 2020 and is expected to register the highest CAGR in the upcoming period due to a rise in research funding for new startups. For instance, Twentyeight-Seven Therapeutics (28-7), a biotechnology company focused on modulating non-coding RNA (ncRNA) biology to develop treatments for cancer and other diseases, announced the successful completion of its USD 65 million Series A financing in 2018. The funding will be used to advance 28-7's lead program, aimed at the discovery and development of small molecules that increase the levels of the tumor suppressor microRNA (miRNA), Let-7, into serious cancer indications.

For a better understanding of the market adoption of miRNA, the market is analyzed based on its worldwide presence in the countries such as North America (United States, Canada, and the Rest of North America), Europe (Germany, France, Italy, Spain, United Kingdom and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, and Rest of APAC), and Rest of World. North America will dominate the miRNA market on account of the rising number of clinical trials for the development of novel therapeutics, and the increase in recent product launches in the region. In September 2016, Amgen and Arrowhead Pharmaceuticals signed two licensing and collaboration deals to develop miRNA-based therapies for cardiovascular diseases. Some of the major players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., Horizon Discovery Ltd., Synlogic, QIAGEN, GeneCopoeia, Inc., New England Biolabs, Quantabio, NanoString, and BioGenex. Several M&As along with partnerships have been undertaken by these players to boost their presence in different regions.

Products


Companies

Merck KGaA, Thermo Fisher Scientific, Inc., Horizon Discovery Ltd., Synlogic, QIAGEN, GeneCopoeia, Inc., New England Biolabs, Quantabio, NanoString, and BioGenex

Table of Contents

Table of Contents

1 MARKET INTRODUCTION

1.1. Market Definitions

1.2. Objective of the Study

1.3. Limitation

1.4. Stake Holders

1.5. Currency Used in Report

1.6. Scope of the Global miRNA Market Study

2 RESEARCH METHODOLOGY OR ASSUMPTION

2.1. Research Methodology for the Global miRNA Market

2.1.1. Main Objective of the Global miRNA Market

3 MARKET SYNOPSIS

4 EXECUTIVE SUMMARY

5 GLOBAL miRNA MARKET REVENUE (USD BN), 2019-2027F

6 MARKET INSIGHTS BY PRODUCTS

6.1. Instruments

6.2. Consumables

7 MARKET INSIGHTS BY SERVICES

7.1. Service Type

7.2. Specimen

8 MARKET INSIGHTS BY APPLICATION

8.1. Cancer

8.2. Infectious Diseases

8.3. Immunological Disorder

8.4. Cardiovascular Disease

8.5. Neurological Disease

8.6. Others

9 MARKET INSIGHTS BY END-USER

9.1. Biotechnology & Pharmaceutical Companies

9.2. Academic & Government Research Institutes

9.3. Other end-users

10 MARKET INSIGHTS BY REGION

10.1. North America miRNA Market

10.1.1. United States

10.1.2. Canada

10.1.3. Rest of North America

10.2. Europe miRNA Market

10.2.1. Germany

10.2.2. France

10.2.3. United Kingdom

10.2.4. Italy

10.2.5. Spain

10.2.6. Rest of Europe

10.3. Asia Pacific miRNA Market

10.3.1. China

10.3.2. Japan

10.3.3. India

10.3.4. Australia

10.3.5. Rest of Asia Pacific

10.4. Rest of the World miRNA Market

11 DEMAND AND SUPPLY SIDE ANALYSIS

11.1. Demand Side Analysis

11.2. Supply Side Analysis

11.2.1. Top Product Launches

11.2.2. Top Business Partnerships

11.2.3. Top Business Expansions, Investments and Divestitures

11.2.4. Top Merger and Acquisitions

12 VALUE CHAIN ANALYSIS

13 GLOBAL MIRNA MARKET TRENDS & INSIGHTS

14 GLOBAL MIRNA MARKET DYNAMICS

14.1. Market Drivers

14.2. Market Challenges

14.3. Impact Analysis

15 GLOBAL MIRNA MARKET OPPORTUNITIES

16 COMPETITIVE SCENARIO

16.1. Porter's Five Forces Analysis

16.1.1. Bargaining power of Supplier

16.1.2. Bargaining power of Buyer

16.1.3. Industry Rivalry

16.1.4. Availability of Substitute

16.1.5. Threat of new Entrants

17 COMPANY PROFILED

17.1. Merck KGaA

17.2. Thermo Fisher Scientific, Inc.

17.3. Horizon Discovery Ltd.

17.4. Synlogic

17.5. QIAGEN

17.6. GeneCopoeia, Inc.

17.7. New England Biolabs

17.8. Quantabio

17.9. NanoString

17.10. BioGenex

18 DISCLAIMER

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