Synthetic Biology Market: Current Analysis and Forecast (2021-2027)

Region:Global

Author(s):

Product Code:UMHE21512

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Published on

November 2021

Total pages

349

Table of Content

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About the Report

About the Report

Synthetic biology is a developing area of biological research that syndicates both science and engineering. It mainly assists in designing and construction of the new biological devices, parts, and systems that are not present in nature and the redesigning of the existing biological systems. The advancements in nano-scale technologies are contributing to advances in synthetics biology. There are mainly two approaches that are being utilized in synthetic biologies such as the bottom-up approach and top-down approach. In the bottom-up approach, there is designing and construction of de novo biological devices or systems that do not exist in nature while in the top-down approach there is the re-designing and fabrication of already existing biological systems to produce synthetics products. The products synthesized by these approaches are utilized in many industries such as energy, bioplastics, environmental, pharmaceutical & diagnostics.

The demand for the Synthetic Biology market is increasing on account of the high investments in the R&D sector. The R&D sector has generally remained capital-intensive owing to long development periods and approval cycles. R&D funding and expenditure have witnessed constant growth over the years. Pharmaceuticals, as well as biotechnology companies, invest highly in research for the production of molecules to cater to the growing needs of the healthcare industry and to prevent the onset of new diseases. The R&D sector in the global pharmaceutical & Biotechnology industry accounts for about 80% of the overall R&D expenditure in the life sciences industry. Moreover, the declining cost of DNA sequencing and synthesizing, and rising investments in the market are boosting the growth of the Synthetic biology market. Furthermore, the increasing demand for biofuels, rising awareness in emerging economies offer remunerative growth opportunities in the market.

However, some of the restraints in the market are Biosafety, biosecurity, and ethical concerns.

Based on Tools, the market is fragmented into Oligonucleotides and Synthetic DNA, Enzymes, Cloning Technologies Kits, Synthetic Cells, Chassis Organisms, and Xeno-nucleic Acids. The oligonucleotides & synthetic DNA segment dominated the market in 2020 and is expected to grow at lucrative during the forecasted period owing to increasing demand for synthetic genes, synthetic DNA, and synthetic RNA which are employed in a wide range of applications. Oligonucleotide synthesis is a rapidly growing process that involves the chemical synthesis of small fragments of nucleic acids with a well-defined sequence. This technique is highly used to provide rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Moreover, it is used for the molecular diagnosis of several infectious diseases such as hepatitis, SARS-COV2, and cancer. Oligonucleotides can unravel cellular function, and help in the development of new therapeutics. In February 2021, Sarepta Therapeutics Inc., the leader in precision genetic medicine for rare diseases, announced the U.S. Food and Drug Administration (FDA) approval of AMONDYS 45 (casimersen). AMONDYS 45 is an antisense oligonucleotide from Sarepta's phosphorodiamidate morpholino oligomer (PMO) platform, indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation amenable to exon 45 skipping.

Based on Technology, the market is bifurcated into Gene Synthesis, Genome Engineering, Sequencing, Bioinformatics, Site-directed Mutagenesis, Cloning, Measurement and Modeling, Microfluidics, and Nanotechnology. The Gene Synthesis segment dominated the market in 2020 and is expected to grow at lucrative during the forecasted period owing to the growing demand for synthetic DNA, synthetic RNA, and oligonucleotides across various application industries. Gene Synthesis is very useful in genome engineering l which increases its attractiveness and value. Gene synthesis is highly exploited in efficient genome editing and genome targeting. Moreover, the increasing funding in genomics, focus on personalized medicine and other factors, such as patient-centered approach is fueling the market growth.

Based on Application, the market is bifurcated into Pharmaceuticals & Diagnostics, Chemicals, Medical Biofuels, Bioplastics, and Others (Environment, Agriculture & Aquaculture). The Medical segment dominated the market in 2020 and is expected to grow at lucrative during the forecasted period owing to several factors such as the extensive research on new and better treatments, coupled with the availability of huge private and public funding for the discovery of novel therapies. Synthetic biology is widely exploited for drug screening and discovery and can be used to discover new drug targeting sites. With the rapid development of synthetic biology, new tools in bioinformatics can be used to analyze potential drug targets. Computational biology and new technology can rapidly identify true protein-coding sequences from DNA sequence data, providing accurate predictions of coding vs non-coding sequences. In January 2021, Novozymes launched Frontia GlutenEx which helps wheat processors to increase their gluten protein recovery and, at the same time, cut down on energy consumption.

For a better understanding of the market adoption of Synthetic Biology, the market is analyzed based on its worldwide presence in the countries such as North America (United States, Canada, and the Rest of North America), Europe (Germany, France, Spain, United Kingdom and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, and Rest of APAC), and Rest of World. North America will dominate the Synthetic Biology market on account of the rise in the number of well-established synthetic biology companies and research institutes in the Canada and US, and a large number of ongoing research studies and growth of the overall healthcare sector on a global scale. Moreover, significant R&D spending is one of the key factors contributing to the growing demand for synthetic biology tools and technologies among academic & research institutes and healthcare companies in North America. Some of the major players operating in the market include Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Inc., Novozymes A/S, Ginkgo Bioworks, Amyris, Precigen, GenScript Biotech Corporation, Twist Bioscience, and Synthetic Genomics. Several M&As along with partnerships have been undertaken by these players to boost their presence in different regions.

Products


Companies

Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Inc., Novozymes A/S, Ginkgo Bioworks, Amyris, Precigen, GenScript Biotech Corporation, Twist Bioscience, and Synthetic Genomics

Table of Contents

Table of Contents

1 MARKET INTRODUCTION

1.1. Market Definitions

1.2. Limitation

1.3. Stake Holders

1.4. Currency used in Report

2 RESEARCH METHODOLOGY OR ASSUMPTION

2.1. Research Process of the Synthetic Biology Market

2.2. Research Methodology of the Synthetic Biology Market

2.3. Forecasting Method

2.4. Respondent Profile

2.5. Main Objective of the Synthetic Biology Market Study

3 MARKET SYNOPSIS

4 EXECUTIVE SUMMARY

5 GLOBAL SYNTHETIC BIOLOGY MARKET COVID-19 IMPACT

6 GLOBAL SYNTHETIC BIOLOGY MARKET REVENUE (USD), 2019-2027F

7 MARKET INSIGHTS BY TOOLS

7.1. Oligonucleotides and Synthetic DNA

7.2. Enzymes

7.3. Cloning Technologies Kits

7.4. Synthetic Cells

7.5. Chassis Organisms

7.6. Xeno-nucleic Acids

8 MARKET INSIGHTS BY TECHNOLOGY

8.1. Gene Synthesis

8.2. Genome Engineering

8.3. Sequencing

8.4. Bioinformatics

8.5. Site-directed Mutagenesis

8.6. Cloning

8.7. Measurement and Modeling

8.8. Microfluidics

8.9. Nanotechnology

9 MARKET INSIGHTS BY APPLICATION

9.1. Pharmaceuticals & Diagnostics

9.2. Chemicals

9.3. Medical

9.4. Biofuels

9.5. Bioplastics

9.6. Others (Environment, Agriculture & Aquaculture)

10 MARKET INSIGHTS BY REGION

10.1. North America Synthetic Biology Market

10.1.1. United States

10.1.2. Canada

10.1.3. Rest of North America

10.2. Europe Synthetic Biology Market

10.2.1. Germany

10.2.2. U.K.

10.2.3. France

10.2.4. Spain

10.2.5. Rest of Europe

10.3. Asia Pacific Synthetic Biology Market

10.3.1. China

10.3.2. Japan

10.3.3. India

10.3.4. Australia

10.3.5. Rest of Asia Pacific

10.4. Rest of World Synthetic Biology Market

11 SYNTHETIC BIOLOGY MARKET DYNAMICS

11.1. Market Drivers

11.2. Market Challenges

11.3. Impact Analysis

12 SYNTHETIC BIOLOGY MARKET OPPORTUNITIES

13 SYNTHETIC BIOLOGY MARKET TRENDS

14 LEGAL & REGULATORY FRAMEWORK

15 DEMAND AND SUPPLY SIDE ANALYSIS

15.1. Demand Side Analysis

15.2. Supply Side Analysis

15.2.1. Top Product Launches

15.2.2. Top Business Partnerships

15.2.3. Top Business Expansions, Investments and Divestitures

15.2.4. Top Merger and Acquisitions

16 VALUE CHAIN ANALYSIS

17 COMPETITIVE SCENARIO

17.1. Competitive Landscape

17.1.1. Company Shares, By Revenue

18 COMPANY PROFILED

18.1. Thermo Fisher Scientific

18.2. Merck KGaA

18.3. Agilent Technologies, Inc.

18.4. Novozymes A/S

18.5. Ginkgo Bioworks

18.6. Amyris

18.7. Precigen

18.8. GenScript Biotech Corporation

18.9. Twist Bioscience

18.10. Synthetic Genomics

19 DISCLAIMER

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