Nucleic Acid Based Gene Therapy Market Global Report 2020-30

Region:Global

Author(s):

Product Code:7614

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Published on

April 2020

Total pages

200

Table of Content

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About the Report

About the Report

The nucleic acid-based gene therapy market consists of sales of nucleic acid-based gene therapy products and services. Gene therapy is used for correcting defective genes that are responsible for disease development. Moreover, nucleic acid-based therapeutics are used to treat genetic disorders and diseases for which there exists no permanent cure such as anaemia, sickle cell, cystic fibrosis, diabetes, and thalassemia.
 
The global nucleic acid based gene therapy market was worth USD 557.47 million in 2019. It is expected to grow at a compound annual growth rate (CAGR) of 10.00% and reach USD 816.18 million by 2023.
 
The nucleic acid-based gene therapy market covered in this report is segmented by technology into anti-sence and anti-gene, short inhibitory sequences, gene transfer therapy, nucleoside analogs, ribozymes, aptamers, others. It is also segmented by application into oncology, muscular dystrophy/ muscular disorders, rare diseases.
 
Rising financial support by the government and the companies is projected to drive the demand for nucleic acid based gene therapy. Nucleic acid therapeutics are analogs of naturally occurring acids or proteins responsible for genetic expression. The traditional therapies do not have any cure for the treatment of diseases such as cystic fibrosis, hemophilia, sickle cell anaemia, thalassemia, and diabetes. Genetic profiling and molecular target identification form the backbone of these classes of drugs. Nucleic acid medication has greater potential for the treatment of these diseases, as they target the genetic basis of diseases and have a permanent cure. Rising financial support by the government and the companies dealing in the market for gene therapy is expected to contribute to increasing the demand for nucleic acid-based gene therapies. For instance in October 2019, the USA National Institutes of Health (NIH) announced plans to invest USD 100 million for the next four years to cure HIV and sickle cell disease with gene therapies. The government support for gene therapies will contribute to the growth of the market.
 
Stringent regulations imposed on gene therapies raises the price of gene therapies, which in turn hinders the demand for nucleic acid-based gene therapies. The excessive regulatory oversights create an expensive and elongated route for approval increasing the expenses. According to Foundation for Economic Education (FEE), unlike other drugs approved or regulated by the Food and Drug Administration (FDA), gene therapies are not only subject to the regulatory structure of FDA, but also the Recombinant DNA Advisory Committee and Office of Biotechnology Activities. Also, as estimated by FEE, an approved gene therapy drug cost nearly USD 5.0 billion, which is five times higher than that of the average cost of FDA approval. The high cost of gene therapeutics drugs places them beyond the financial reach of the populace. This scenario is anticipated to restrain the market growth of the nucleic acid-based gene therapy market.
 
In May 2018, Vectalys, a leading biotechnology company specializing in the manufacturing of high-quality solutions for gene delivery and FlashCell, a company engaged in developing non-integrated lentiviral delivered RNA Therapeutics announced the merger to create Flash Therapeutics, a privately held gene therapy company developing cell and gene therapeutics. The new company Flash Therapeutics is expected to focus on the development of RNA therapeutics based on LentiFlash, a non-integrative lentiviral delivery technology for incurable diseases.
 
Major players in the market are Wave Life Sciences, Imugene, Caperna, Phylogica, Protagonist Therapeutics, Benitec Biopharma, EGEN, BioMedica, Transgene and Copernicus Therapeutics.

Products

Products

1) By Technology: Anti-Sence and Anti-Gene; Short Inhibitory Sequences; Gene Transfer Therapy; Nucleoside Analogs; Ribozymes; Aptamers; Others; 2) By Application: Oncology, Muscular Dystrophy/ Muscular Disorders, Rare Diseases


Companies

Celsion Corporation; Wave Life Sciences; Imugene; Caperna; Phylogica; Protagonist Therapeutics; Benitec Biopharma; EGEN; BioMedica; Transgene; Copernicus Therapeutics

Table of Contents

Table of Contents

1. Executive Summary

2. Nucleic Acid Based Gene Therapy Market Market Characteristics

3. Nucleic Acid Based Gene Therapy Market Market Size And Growth

3.1. Global Nucleic Acid Based Gene Therapy Market Historic Market, 2015-2019, USD Billion

3.1.1. Drivers Of The Market

3.1.2. Restraints On The Market

3.2. Global Nucleic Acid Based Gene Therapy Market Forecast Market, 2019-2023F, 2025F, 2030F, USD Billion

3.2.1. Drivers Of The Market

3.2.2. Restraints On the Market

4. Nucleic Acid Based Gene Therapy Market Market Segmentation

4.1. Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Anti-Sence and Anti-Gene

Short Inhibitory Sequences

Gene Transfer Therapy

Nucleoside Analogs

Ribozymes

Aptamers

Others

4.2. Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Monogenetic Disorders

Multi-gentic Disorders

5. Nucleic Acid Based Gene Therapy Market Market Regional And Country Analysis

5.1. Global Nucleic Acid Based Gene Therapy Market Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

5.2. Global Nucleic Acid Based Gene Therapy Market Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

6. Asia-Pacific Nucleic Acid Based Gene Therapy Market Market

6.1. Asia-Pacific Nucleic Acid Based Gene Therapy Market Market Overview

6.2. Asia-Pacific Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

7. China Nucleic Acid Based Gene Therapy Market Market

7.1. China Nucleic Acid Based Gene Therapy Market Market Overview

7.2. China Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F,USD Billion

8. India Nucleic Acid Based Gene Therapy Market Market

8.1. India Nucleic Acid Based Gene Therapy Market Market Overview

8.2. India Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

9. Japan Nucleic Acid Based Gene Therapy Market Market

9.1. Japan Nucleic Acid Based Gene Therapy Market Market Overview

9.2. Japan Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

10. Australia Nucleic Acid Based Gene Therapy Market Market

10.1. Australia Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

11. Indonesia Nucleic Acid Based Gene Therapy Market Market

11.1. Indonesia Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

12. South Korea Nucleic Acid Based Gene Therapy Market Market

12.1. South Korea Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

13. Western Europe Nucleic Acid Based Gene Therapy Market Market

13.1. Western Europe Nucleic Acid Based Gene Therapy Market Market Overview

13.2. Western Europe Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

14. UK Nucleic Acid Based Gene Therapy Market Market

14.1. UK Nucleic Acid Based Gene Therapy Market Market Overview

14.2. UK Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

15. Germany Nucleic Acid Based Gene Therapy Market Market

15.1. Germany Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

16. France Nucleic Acid Based Gene Therapy Market Market

16.3. France Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

17. Eastern Europe Nucleic Acid Based Gene Therapy Market Market

17.1. Eastern Europe Nucleic Acid Based Gene Therapy Market Market Overview

17.2. Eastern Europe Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

18. Russia Nucleic Acid Based Gene Therapy Market Market

18.1. Russia Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

19. North America Nucleic Acid Based Gene Therapy Market Market

19.1. North America Nucleic Acid Based Gene Therapy Market Market Overview

19.2. North America Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

20. USA Nucleic Acid Based Gene Therapy Market Market

20.1. USA Nucleic Acid Based Gene Therapy Market Market Overview

20.2. USA Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

21. South America Nucleic Acid Based Gene Therapy Market Market

21.1. South America Nucleic Acid Based Gene Therapy Market Market Overview

21.2. South America Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

22. Brazil Nucleic Acid Based Gene Therapy Market Market

22.1. Brazil Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

23. Middle East Nucleic Acid Based Gene Therapy Market Market

23.1. Middle East Nucleic Acid Based Gene Therapy Market Market Overview

23.2. Middle East Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

24. Africa Nucleic Acid Based Gene Therapy Market Market

24.1. Africa Nucleic Acid Based Gene Therapy Market Market Overview

24.2. Africa Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

25. Nucleic Acid Based Gene Therapy Market Market Competitive Landscape And Company Profiles

25.1. Nucleic Acid Based Gene Therapy Market Market Competitive Landscape

25.2. Nucleic Acid Based Gene Therapy Market Market Company Profiles

25.2.1. Celsion Corporation

25.2.1.1. Overview

25.2.1.2. Products and Services

25.2.1.3. Strategy

25.2.1.4. Financial Performance

25.2.2. Wave Life Sciences

25.2.2.1. Overview

25.2.2.2. Products and Services

25.2.2.3. Strategy

25.2.2.4. Financial Performance

25.2.3. Imugene

25.2.3.1. Overview

25.2.3.2. Products and Services

25.2.3.3. Strategy

25.2.3.4. Financial Performance

25.2.4. Caperna

25.2.4.1. Overview

25.2.4.2. Products and Services

25.2.4.3. Strategy

25.2.4.4. Financial Performance

25.2.5. Phylogica

25.2.5.1. Overview

25.2.5.2. Products and Services

25.2.5.3. Strategy

25.2.5.4. Financial Performance

26. Key Mergers And Acquisitions In The Nucleic Acid Based Gene Therapy Market Market

27. Nucleic Acid Based Gene Therapy Market Market Trends And Strategies

28. Nucleic Acid Based Gene Therapy Market Market Future Outlook and Potential Analysis

29. Appendix

29.1. Abbreviations

29.2. Currencies

29.3. Research Inquiries

29.4. The Business Research Company

29.5. Copyright And Disclaimer

 


List of Figure

Figure 1: Global Historic Market Growth, 2015-2019, USD Billion

Figure 2: Global Forecast Market Growth, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 3: Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 4: Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 5: Global Nucleic Acid Based Gene Therapy Market Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 6: Global Nucleic Acid Based Gene Therapy Market Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 7: Asia-Pacific, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 8: China, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 9: India, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 10: Japan, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 11: Australia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 12: Indonesia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 13: South Korea, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 14: Western Europe, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 15: UK, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 16: Germany, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 17: France, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 18: Eastern Europe, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 19: Russia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 20: North America, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 21: USA, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 22: South America, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 23: Brazil, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 24: Middle East, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 25: Africa, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Figure 26: Celsion Corporation Financial Performance

Figure 27: Wave Life Sciences Financial Performance

Figure 28: Imugene Financial Performance

Figure 29: Caperna Financial Performance

Figure 30: Phylogica Financial Performance


List of Table

Table 1: Global Historic Market Growth, 2015-2019, USD Billion

Table 2: Global Forecast Market Growth, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 3: Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 4: Global Nucleic Acid Based Gene Therapy Market Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 5: Global Nucleic Acid Based Gene Therapy Market Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 6: Global Nucleic Acid Based Gene Therapy Market Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 7: Asia-Pacific, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 8: China, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 9: India, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 10: Japan, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 11: Australia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 12: Indonesia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 13: South Korea, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 14: Western Europe, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 15: UK, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 16: Germany, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 17: France, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 18: Eastern Europe, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 19: Russia, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 20: North America, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 21: USA, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 22: South America, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 23: Brazil, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 24: Middle East, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 25: Africa, Nucleic Acid Based Gene Therapy Market Market, Segmentation By Technology, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, USD Billion

Table 26: Celsion Corporation Financial Performance

Table 27: Wave Life Sciences Financial Performance

Table 28: Imugene Financial Performance

Table 29: Caperna Financial Performance

Table 30: Phylogica Financial Performance

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