Neurovascular Stents-Medical Devices Pipeline Assessment, 2017

Table of Contents

1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 4

1.2 List of Figures 5

2 Introduction 6

2.1 Neurovascular Stents Overview 6

3 Products under Development 7

3.1 Neurovascular Stents-Pipeline Products by Stage of Development 7

3.2 Neurovascular Stents-Pipeline Products by Territory 8

3.3 Neurovascular Stents-Pipeline Products by Regulatory Path 9

3.4 Neurovascular Stents-Pipeline Products by Estimated Approval Date 10

3.5 Neurovascular Stents-Ongoing Clinical Trials 11

4 Neurovascular Stents-Pipeline Products under Development by Companies 12

4.1 Neurovascular Stents Companies-Pipeline Products by Stage of Development 12

4.2 Neurovascular Stents-Pipeline Products by Stage of Development 13

5 Neurovascular Stents Companies and Product Overview 14

5.1 Aneuclose LLC Company Overview 14

5.1.1 Aneuclose LLC Pipeline Products & Ongoing Clinical Trials Overview 14

5.2 Apeliotus Technologies Company Overview 15

5.2.1 Apeliotus Technologies Pipeline Products & Ongoing Clinical Trials Overview 15

5.3 Codman & Shurtleff Inc Company Overview 16

5.3.1 Codman & Shurtleff Inc Pipeline Products & Ongoing Clinical Trials Overview 16

5.4 Cordis Corp Company Overview 18

5.4.1 Cordis Corp Pipeline Products & Ongoing Clinical Trials Overview 18

5.5 Gaudi Vascular, Inc. Company Overview 19

5.5.1 Gaudi Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 19

5.6 MicroPort Scientific Corp Company Overview 20

5.6.1 MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 20

5.7 MicroVention, Inc. Company Overview 21

5.7.1 MicroVention, Inc. Pipeline Products & Ongoing Clinical Trials Overview 21

5.8 Neurosigma Inc Company Overview 25

5.8.1 Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 25

5.9 NSVascular, Inc. Company Overview 26

5.9.1 NSVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26

5.10 Palmaz Scientific Inc Company Overview 27

5.10.1 Palmaz Scientific Inc Pipeline Products & Ongoing Clinical Trials Overview 27

5.11 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 28

5.11.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 28

5.12 University of California Los Angeles Company Overview 29

5.12.1 University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 29

6 Neurovascular Stents- Recent Developments 30

6.1 Apr 27, 2017: Boston Scientific Announces Results For First Quarter 2017 30

6.2 Apr 23, 2017: Bard Announces First Quarter Results 31

6.3 Mar 30, 2017: MPSC Announces 2016 Annual Results 31

6.4 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 33

6.5 Feb 16, 2017: InspireMD Provides Year End Business Update and Reports Financial Results for the Fourth Quarter and Year Ended December 31, 2016 36

6.6 Feb 14, 2017: MicroPort Receives CFDA Approval for APOLLO Intracranial Stent System in Large Sizes 37

6.7 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 38

6.8 Feb 02, 2017: Boston Scientific Announces Results For Fourth Quarter And Full Year Ended December 31, 2016 38

6.9 Jan 26, 2017: Bard Announces Fourth Quarter Results 40

6.10 Dec 15, 2016: MicroPort NeuroTech Attends CINS 2016 40

6.11 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 41

6.12 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 44

6.13 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 44

6.14 Nov 14, 2016: InspireMD Reports Financial Results for the Third Quarter Ended September 30, 2016 45

6.15 Oct 26, 2016: Boston Scientific Announces Results For Third Quarter 2016 47

6.16 Oct 25, 2016: Bard Announces Third Quarter Results 49

6.17 Oct 10, 2016: Professor Ian Meredith To Join Boston Scientific As Executive Vice President And Global Chief Medical Officer 50

6.18 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 50

6.19 Sep 07, 2016: InspireMD Appoints Thomas Kester to Board of Directors 51

6.20 Aug 30, 2016: MPSC Announces 2016 Interim Results 52

6.21 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 53

6.22 Aug 09, 2016: InspireMD Reports Financial Results for the Second Quarter Ended June 30, 2016 56

6.23 Jul 28, 2016: Boston Scientific Announces Results For Second Quarter 2016 58

6.24 Jul 26, 2016: Bard Announces Second Quarter Results 60

6.25 Jul 21, 2016: InspireMD Regains Compliance With NYSE MKT Listing Standards 61

6.26 Jul 13, 2016: Boston Scientific Elects Yoshiaki Fujimori to Board of Directors 61

6.27 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 61

6.28 Jun 08, 2016: Boston Scientific Announces Restructuring Program to Support Long-Term Growth and Innovation 62

6.29 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 62

6.30 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 63

7 Appendix 67

7.1 Methodology 67

7.2 About GlobalData 70

7.3 Contact Us 70

7.4 Disclaimer 70

List of Figure

1.2 List of Figures

Figure 1: Neurovascular Stents-Pipeline Products by Stage of Development 7

Figure 2: Neurovascular Stents-Pipeline Products by Territory 8

Figure 3: Neurovascular Stents-Pipeline Products by Regulatory Path 9

Figure 4: Neurovascular Stents-Pipeline Products by Estimated Approval Date 10

Figure 5: Neurovascular Stents-Ongoing Clinical Trials 11

List of Table

1.1 List of Tables

Table 1: Neurovascular Stents-Pipeline Products by Stage of Development 7

Table 2: Neurovascular Stents-Pipeline Products by Territory 8

Table 3: Neurovascular Stents-Pipeline Products by Regulatory Path 9

Table 4: Neurovascular Stents-Pipeline Products by Estimated Approval Date 10

Table 5: Neurovascular Stents-Ongoing Clinical Trials 11

Table 6: Neurovascular Stents Companies-Pipeline Products by Stage of Development 12

Table 7: Neurovascular Stents-Pipeline Products by Stage of Development 13

Table 8: Aneuclose LLC Pipeline Products & Ongoing Clinical Trials Overview 14

Table 9: Aneurysm Occlusion Saddle-Product Status 14

Table 10: Aneurysm Occlusion Saddle-Product Description 14

Table 11: Apeliotus Technologies Pipeline Products & Ongoing Clinical Trials Overview 15

Table 12: Polymer Stent for Cerebral Aneurysms-Product Status 15

Table 13: Polymer Stent for Cerebral Aneurysms-Product Description 15

Table 14: Codman & Shurtleff Inc Pipeline Products & Ongoing Clinical Trials Overview 16

Table 15: Covered Stent-Product Status 16

Table 16: Covered Stent-Product Description 16

Table 17: Next Generation Balloon Expandable Stent-Product Status 16

Table 18: Next Generation Balloon Expandable Stent-Product Description 17

Table 19: Self-Expanding Stent-Product Status 17

Table 20: Self-Expanding Stent-Product Description 17

Table 21: Cordis Corp Pipeline Products & Ongoing Clinical Trials Overview 18

Table 22: Flow Diverter-Product Status 18

Table 23: Flow Diverter-Product Description 18

Table 24: Gaudi Vascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 19

Table 25: Intracranial Stent-Product Status 19

Table 26: Intracranial Stent-Product Description 19

Table 27: MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 20

Table 28: Vertebral Artery Stent-Product Status 20

Table 29: Vertebral Artery Stent-Product Description 20

Table 30: MicroVention, Inc. Pipeline Products & Ongoing Clinical Trials Overview 21

Table 31: Coated Stent-Product Status 21

Table 32: Coated Stent-Product Description 21

Table 33: FRED Flow-Diverting Stent-Product Status 22

Table 34: FRED Flow-Diverting Stent-Product Description 22

Table 35: MicroVention, Inc.-Ongoing Clinical Trials Overview 23

Table 36: FRED Flow-Diverting Stent-Pivotal Study of the MicroVention Flow Re-Direction Endoluminal Device (FRED) Stent System in the Treatment of Intracranial Aneurysms 24

Table 37: Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 25

Table 38: Thin Film Nitinol Flow Diverting Stent-Product Status 25

Table 39: Thin Film Nitinol Flow Diverting Stent-Product Description 25

Table 40: NSVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26

Table 41: Flow-Diverting TFN Stent-Product Status 26

Table 42: Flow-Diverting TFN Stent-Product Description 26

Table 43: Palmaz Scientific Inc Pipeline Products & Ongoing Clinical Trials Overview 27

Table 44: Micro Neuro-Stent-Product Status 27

Table 45: Micro Neuro-Stent-Product Description 27

Table 46: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 28

Table 47: Flow Diversion Intracranial Stent-Product Status 28

Table 48: Flow Diversion Intracranial Stent-Product Description 28

Table 49: University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 29

Table 50: Dual Rotational Stent-Product Status 29

Table 51: Dual Rotational Stent-Product Description 29

Table 52: Glossary 69