Global rat mouse model market report Size, Share, Growth Drivers, Trends, Opportunities & Forecast 2025–2030

Global Rat Mouse Model Market Overview

• The Global Rat Mouse Model Market is valued at USD 1.6 billion, based on a five-year historical analysis. This growth is primarily driven by the increasing prevalence of chronic and infectious diseases, rising demand for personalized medicine, and rapid advancements in genetic engineering technologies such as CRISPR. The market is further supported by robust investment in research and development activities across pharmaceutical, biotechnology, and academic sectors, as well as the growing need for reliable preclinical models in drug discovery and safety assessment .
• Key players in this market are predominantly located in North America and Europe, with the United States and Germany being the most dominant countries. The U.S. benefits from advanced research infrastructure, significant funding for biomedical research, and a high concentration of pharmaceutical and biotechnology companies. Germany's strong emphasis on research and development in life sciences, along with its established academic and industrial networks, further solidifies its position in the market .
• The "21st Century Cures Act," enacted by the U.S. Congress in 2016 and implemented by the U.S. Department of Health and Human Services, aims to accelerate medical product development and bring innovations to patients more efficiently. This regulation streamlines the approval process for new therapies and encourages the use of animal models, including rat and mouse models, in biomedical research by supporting translational science and modernizing clinical trial design requirements .

Global Rat Mouse Model Market Segmentation

By Type:The market is segmented into various types of rat models, including Outbred Rat Models, Inbred Rat Models, Genetically Engineered Rat Models, Immunodeficient Rat Models, Humanized Rat Models, and Others. Among these, Genetically Engineered Rat Models are gaining significant traction due to their application in studying complex diseases and drug responses. The demand for these models is driven by advancements in genetic engineering techniques, such as CRISPR/Cas9, which allow for precise modifications that mimic human diseases more accurately. The increasing use of humanized and immunodeficient models for oncology and immunology research is also notable .

By Mouse Model Type:The mouse model segment includes Inbred Mouse Models, Outbred Mouse Models, Genetically Engineered Mouse Models, Immunodeficient Mouse Models, Humanized Mouse Models, and Others. Genetically Engineered Mouse Models are particularly dominant in this segment due to their critical role in preclinical research and drug development. Their ability to replicate human diseases at a genetic level makes them invaluable for researchers aiming to understand disease mechanisms and test new therapies. The adoption of humanized and immunodeficient mouse models is also rising, especially in immuno-oncology and infectious disease research .

Global Rat Mouse Model Market Competitive Landscape

The Global Rat Mouse Model Market is characterized by a dynamic mix of regional and international players. Leading participants such as Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, Envigo, Horizon Discovery Group plc, genOway, Janvier Labs, Biomedical Research Models (Biomere), InVivo Biosystems, BioIVT, Crown Bioscience, WuXi AppTec, Cyagen Biosciences, GenScript, Covance Inc. contribute to innovation, geographic expansion, and service delivery in this space.

Global Rat Mouse Model Market Industry Analysis

Growth Drivers

• Increasing Demand for Personalized Medicine:The global personalized medicine market is projected to reach $2.5 trillion in future, driven by advancements in genomics and biotechnology. This surge in demand is fostering the development of rat and mouse models that can mimic human diseases more accurately. As pharmaceutical companies invest approximately $83 billion annually in R&D, the need for tailored therapeutic solutions is propelling the growth of animal models that facilitate personalized treatment strategies.
• Advancements in Genetic Engineering Technologies:The global genetic engineering market is expected to exceed $30 billion in future, with CRISPR technology leading the charge. These advancements enable the creation of genetically modified rat and mouse models that are crucial for studying complex diseases. The increasing precision of gene editing tools is enhancing the reliability of preclinical studies, thereby attracting significant investments from biopharmaceutical companies, which allocated over $50 billion to R&D in future.
• Rising Prevalence of Chronic Diseases:Chronic diseases, such as diabetes and cancer, are projected to affect over 1.5 billion people globally in future. This alarming trend is driving the demand for effective research models to understand disease mechanisms and develop new therapies. The World Health Organization reports that chronic diseases account for 71% of all deaths worldwide, emphasizing the urgent need for innovative research solutions, including rat and mouse models, to combat these health challenges.

Market Challenges

• Ethical Concerns Regarding Animal Testing:Ethical issues surrounding animal testing are increasingly influencing research practices. In future, approximately 60% of researchers reported concerns about the ethical implications of using animal models. This has led to stricter regulations and a push for alternative methods, which could hinder the growth of the rat and mouse model market. The ongoing debate over animal welfare is prompting organizations to seek more humane research methodologies, impacting traditional practices.
• High Costs Associated with Model Development:Developing specialized rat and mouse models can cost upwards of $500,000, which poses a significant barrier for smaller research institutions. The financial burden of model creation, coupled with the need for advanced facilities and skilled personnel, limits accessibility for many organizations. As a result, only a fraction of research entities can afford to invest in these models, potentially stifling innovation and slowing down research progress in the field.

Global Rat Mouse Model Market Future Outlook

The future of the rat and mouse model market appears promising, driven by technological advancements and increasing research funding. As biopharmaceutical companies continue to expand their R&D efforts, the demand for innovative animal models will likely rise. Furthermore, collaborations between academia and industry are expected to enhance model development, leading to more effective preclinical studies. The focus on ethical research practices will also shape the evolution of this market, encouraging the adoption of alternative methodologies alongside traditional models.

Market Opportunities

• Expansion of Biopharmaceutical Companies:The biopharmaceutical sector is projected to grow significantly, with investments expected to reach $300 billion in future. This expansion presents opportunities for rat and mouse model providers to cater to the increasing demand for preclinical testing, thereby enhancing their market presence and driving innovation in model development.
• Increasing Collaborations Between Academia and Industry:Collaborative efforts between academic institutions and industry players are on the rise, with over 1,000 partnerships formed in future alone. These collaborations are fostering the development of advanced rat and mouse models, enabling researchers to leverage shared resources and expertise, ultimately accelerating the pace of scientific discovery and therapeutic development.