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Deep Brain Stimulators-Medical Devices Pipeline Assessment, 2016

Deep Brain Stimulators-Medical Devices Pipeline Assessment, 2016


  • Products Id :- GDME0296EPD
  • |
  • Pages: 140
  • |
  • December 2016
  • |
  • |
  Request for Sample Report

Executive Summary

Deep Brain Stimulators-Medical Devices Pipeline Assessment, 2016

Summary

GlobalData's Medical Devices sector report, "Deep Brain Stimulators-Medical Devices Pipeline Assessment, 2016" provides an overview of Deep Brain Stimulators currently in pipeline stage.

The report provides comprehensive information on the pipeline products with comparative analysis of the products at various stages of development. The report reviews major players involved in the pipeline product development. It also provides information about clinical trials in progress, which includes trial phase, trial status, trial start and end dates, and, the number of trials for the key Deep Brain Stimulators pipeline products.

This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts.

*Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type.

Scope

Extensive coverage of the Deep Brain Stimulators under development

The report reviews details of major pipeline products which includes, product description, licensing and collaboration details and other developmental activities

The report reviews the major players involved in the development of Deep Brain Stimulators and list all their pipeline projects

The coverage of pipeline products based on various stages of development ranging from Early Development to Approved / Issued stage

The report provides key clinical trial data of ongoing trials specific to pipeline products

Recent developments in the segment / industry

Reasons To Buy

The report enables you to-

Formulate significant competitor information, analysis, and insights to improve R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of Deep Brain Stimulators under development

Develop market-entry and market expansion strategies

Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline

In-depth analysis of the product's current stage of development, territory and estimated launch date



Contact Us:
Ken Research
Ankur Gupta, Head Marketing & Communications
ankur [@] kenresearch.com
+91-9015378249
www.kenresearch.com

1 Table of Contents

1 Table of Contents 2

1.1 List of Tables 5

1.2 List of Figures 10

2 Introduction 11

2.1 Deep Brain Stimulators Overview 11

3 Products under Development 12

3.1 Deep Brain Stimulators-Pipeline Products by Stage of Development 12

3.2 Deep Brain Stimulators-Pipeline Products by Territory 13

3.3 Deep Brain Stimulators-Pipeline Products by Regulatory Path 14

3.4 Deep Brain Stimulators-Pipeline Products by Estimated Approval Date 15

3.5 Deep Brain Stimulators-Ongoing Clinical Trials 16

4 Deep Brain Stimulators-Pipeline Products under Development by Companies 17

4.1 Deep Brain Stimulators Companies-Pipeline Products by Stage of Development 17

4.2 Deep Brain Stimulators-Pipeline Products by Stage of Development 19

5 Deep Brain Stimulators Companies and Product Overview 21

5.1 Adaptive Neuromodulation GmbH Company Overview 21

5.1.1 Adaptive Neuromodulation GmbH Pipeline Products & Ongoing Clinical Trials Overview 21

5.2 Aleva Neurotherapeutics SA Company Overview 22

5.2.1 Aleva Neurotherapeutics SA Pipeline Products & Ongoing Clinical Trials Overview 22

5.3 Boston Scientific Corp Company Overview 25

5.3.1 Boston Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 25

5.4 Brainsway Ltd Company Overview 30

5.4.1 Brainsway Ltd Pipeline Products & Ongoing Clinical Trials Overview 30

5.5 Cerene Biomedics, Inc. Company Overview 40

5.5.1 Cerene Biomedics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 40

5.6 Cerevast Therapeutics Inc Company Overview 41

5.6.1 Cerevast Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 41

5.7 Children's Hospital Boston Company Overview 42

5.7.1 Children's Hospital Boston Pipeline Products & Ongoing Clinical Trials Overview 42

5.8 Cleveland Medical Devices Inc Company Overview 43

5.8.1 Cleveland Medical Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 43

5.9 Clinatec Company Overview 44

5.9.1 Clinatec Pipeline Products & Ongoing Clinical Trials Overview 44

5.10 Deep Brain Innovations, LLC Company Overview 45

5.10.1 Deep Brain Innovations, LLC Pipeline Products & Ongoing Clinical Trials Overview 45

5.11 Duke University Company Overview 50

5.11.1 Duke University Pipeline Products & Ongoing Clinical Trials Overview 50

5.12 Functional Neuromodulation Inc. Company Overview 51

5.12.1 Functional Neuromodulation Inc. Pipeline Products & Ongoing Clinical Trials Overview 51

5.13 Highland Instruments, Inc. Company Overview 53

5.13.1 Highland Instruments, Inc. Pipeline Products & Ongoing Clinical Trials Overview 53

5.14 Massachusetts General Hospital Company Overview 54

5.14.1 Massachusetts General Hospital Pipeline Products & Ongoing Clinical Trials Overview 54

5.15 Massachusetts Institute of Technology Company Overview 56

5.15.1 Massachusetts Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 56

5.16 Mayo Clinic US Company Overview 57

5.16.1 Mayo Clinic US Pipeline Products & Ongoing Clinical Trials Overview 57

5.17 Medtronic plc Company Overview 58

5.17.1 Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 58

5.18 National Cheng-Kung University Hospital Company Overview 62

5.18.1 National Cheng-Kung University Hospital Pipeline Products & Ongoing Clinical Trials Overview 62

5.19 NeuroPro Technologies Inc Company Overview 63

5.19.1 NeuroPro Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 63

5.20 Neurosigma Inc Company Overview 64

5.20.1 Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 64

5.21 Newronika s.r.l. Company Overview 66

5.21.1 Newronika s.r.l. Pipeline Products & Ongoing Clinical Trials Overview 66

5.22 Nuraleve Inc. Company Overview 67

5.22.1 Nuraleve Inc. Pipeline Products & Ongoing Clinical Trials Overview 67

5.23 Soterix Medical Inc Company Overview 68

5.23.1 Soterix Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 68

5.24 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 81

5.24.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 81

5.25 St. Jude Medical Inc Company Overview 83

5.25.1 St. Jude Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 83

5.26 SUNY Downstate Medical Center Company Overview 86

5.26.1 SUNY Downstate Medical Center Pipeline Products & Ongoing Clinical Trials Overview 86

5.27 The University of Utah Company Overview 87

5.27.1 The University of Utah Pipeline Products & Ongoing Clinical Trials Overview 87

5.28 University of California Los Angeles Company Overview 89

5.28.1 University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 89

5.29 University of Central Florida Company Overview 91

5.29.1 University of Central Florida Pipeline Products & Ongoing Clinical Trials Overview 91

5.30 University of Illinois Company Overview 93

5.30.1 University of Illinois Pipeline Products & Ongoing Clinical Trials Overview 93

5.31 University of Michigan Company Overview 95

5.31.1 University of Michigan Pipeline Products & Ongoing Clinical Trials Overview 95

5.32 University of Milan Company Overview 96

5.32.1 University of Milan Pipeline Products & Ongoing Clinical Trials Overview 96

5.33 University of Oxford Company Overview 97

5.33.1 University of Oxford Pipeline Products & Ongoing Clinical Trials Overview 97

5.34 University of South Florida Company Overview 98

5.34.1 University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 98

5.35 Wedge Therapeutics Company Overview 99

5.35.1 Wedge Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 99

6 Deep Brain Stimulators- Recent Developments 100

6.1 Nov 28, 2016: Brainsway Reports Continued Financial Growth for Q3 of 2016 100

6.2 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 100

6.3 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 103

6.4 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 103

6.5 Nov 01, 2016: Sheppard Pratt Health System Appoints New Chief Financial Officer 104

6.6 Oct 26, 2016: Boston Scientific Announces Results For Third Quarter 2016 104

6.7 Oct 19, 2016: St. Jude Medical Reports Third Quarter 2016 Results 106

6.8 Oct 13, 2016: Baylor College of Medicine researcher and collaborators awarded grant through NIH BRAIN Initiative 107

6.9 Oct 10, 2016: Professor Ian Meredith To Join Boston Scientific As Executive Vice President And Global Chief Medical Officer 108

6.10 Oct 07, 2016: Directional deep brain stimulation for movement disorders now being used 109

6.11 Oct 06, 2016: St. Jude Medical Announces U.S. Launch and First Implant of New Deep Brain Stimulation System and Directional Lead for Patients Suffering from Movement Disorders 110

6.12 Sep 28, 2016: Soterix Medical Launches PainX tDCS Treatment in Canada with Health Canada Approval 110

6.13 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 111

6.14 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 112

6.15 Aug 17, 2016: Jersey Shore University Medical Center is First Hospital In New Jersey to Offer Deep Transcranial Magnetic Stimulation (DTMS) 114

6.16 Aug 03, 2016: Deep Transcranial Magnetic Stimulation Enables Controlled Opening of Blood-Brain Barrier 115

6.17 Jul 28, 2016: Boston Scientific Announces Results For Second Quarter 2016 115

6.18 Jul 21, 2016: TGA Hazard Alert On Medtronic Neuromodulation Deep Brain Stimulation system pocket adaptors 117

6.19 Jul 20, 2016: St. Jude Medical Reports Second Quarter 2016 Results 117

6.20 Jul 19, 2016: Deep Brain Stimulation Continues To Show Promise For Patients With Mild Alzheimers Disease 119

6.21 Jul 13, 2016: Boston Scientific Elects Yoshiaki Fujimori to Board of Directors 120

6.22 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 120

6.23 Jun 16, 2016: TGA Hazard Alert on Medtronic deep brain stimulation therapy DBS Extension models 7483 and 37086 120

6.24 Jun 16, 2016: St. Jude Medical Broadens Treatment Options for Patients Suffering Movement Disorders with the European Launch of New Deep Brain Stimulation System and Directional Lead 121

6.25 Jun 15, 2016: Soterix Medical awarded $2.5M NIH grant to run Phase-2 Efficacy Trial to treat Aphasia after Stroke with HD-tDCS 121

6.26 Jun 08, 2016: Boston Scientific Announces Restructuring Program to Support Long-Term Growth and Innovation 122

6.27 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 123

6.28 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 123

6.29 May 27, 2016: Aleva Neurotherapeutics Raises USD18 Million in Series C Financing Round 126

6.30 May 17, 2016: Soterix Medical, Announces tDCS-LTE Depression Treatment Partnership Program for Clinicians and Medical Centers based on its Non-invasive Neuromodulation Platform 126

6.31 May 04, 2016: Medtronic Welcomes Karen L. Parkhill as Its New Chief Financial Officer 126

6.32 Apr 06, 2016: Medtronic Statement on U.S. Department of Treasury's Recent Temporary and Proposed Regulations 127

6.33 Apr 04, 2016: Sheppard Pratt Health System Names New President and CEO 128

6.34 Mar 17, 2016: Medtronic Proposes Proxy Access 128

6.35 Mar 01, 2016: Medtronic Reports Third Quarter Financial Results 129

6.36 Feb 19, 2016: Medtronic to Announce Financial Results for Its Third Quarter of Fiscal Year 2016 130

6.37 Feb 17, 2016: FDA Approves Medtronic Deep Brain Stimulation for People with Parkinson's Disease with Recent Onset of Motor Complications 130

6.38 Feb 02, 2016: Clinatec Raises USD10.6 Million in Venture Financing 132

6.39 Feb 01, 2016: Aleva Neurotherapeutics Enters into Agreement with Greatbatch 132

6.40 Feb 01, 2016: Aleva Neurotherapeutics to Raise Funds in Series C Financing 132

6.41 Jan 14, 2016: Soterix Medical Launches PainX tDCS Treatment in EU with CE Approval 132

6.42 Jan 11, 2016: Medtronic Updates Capital Allocation Plans and Fiscal 2016 EPS Guidance 133

6.43 Dec 29, 2015: Soterix Medical Receives CE Mark Approval for 1x1 tDCS Depression Therapy 134

6.44 Dec 14, 2015: The Medtronic Bakken Invitation Award Honors 12 Patients from Around the World for Giving Back 134

6.45 Dec 09, 2015: Medtronic Announces FDA Approval for the Only Full-Body MR Conditional Deep Brain Stimulation Systems 135

7 Appendix 137

7.1 Methodology 137

7.2 About GlobalData 140

7.3 Contact Us 140

7.4 Disclaimer 140

1.2 List of Figures

Figure 1: Deep Brain Stimulators-Pipeline Products by Stage of Development 12

Figure 2: Deep Brain Stimulators-Pipeline Products by Territory 13

Figure 3: Deep Brain Stimulators-Pipeline Products by Regulatory Path 14

Figure 4: Deep Brain Stimulators-Pipeline Products by Estimated Approval Date 15

Figure 5: Deep Brain Stimulators-Ongoing Clinical Trials 16

1.1 List of Tables

Table 1: Deep Brain Stimulators-Pipeline Products by Stage of Development 12

Table 2: Deep Brain Stimulators-Pipeline Products by Territory 13

Table 3: Deep Brain Stimulators-Pipeline Products by Regulatory Path 14

Table 4: Deep Brain Stimulators-Pipeline Products by Estimated Approval Date 15

Table 5: Deep Brain Stimulators-Ongoing Clinical Trials 16

Table 6: Deep Brain Stimulators Companies-Pipeline Products by Stage of Development 17

Table 7: Deep Brain Stimulators-Pipeline Products by Stage of Development 19

Table 8: Adaptive Neuromodulation GmbH Pipeline Products & Ongoing Clinical Trials Overview 21

Table 9: CR-Capable Implant-Product Status 21

Table 10: CR-Capable Implant-Product Description 21

Table 11: Aleva Neurotherapeutics SA Pipeline Products & Ongoing Clinical Trials Overview 22

Table 12: directSTIM-Product Status 22

Table 13: directSTIM-Product Description 23

Table 14: spiderSTIM-Product Status 23

Table 15: spiderSTIM-Product Description 23

Table 16: Aleva Neurotherapeutics SA-Ongoing Clinical Trials Overview 24

Table 17: spiderSTIM-Evaluation of Directional Recording and Stimulation Using the spiderSTN During the Implantation of DBS Leads 24

Table 18: Boston Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 25

Table 19: Directional Lead-Product Status 25

Table 20: Directional Lead-Product Description 26

Table 21: Enspire DBS Therapy System-Stroke-Product Status 26

Table 22: Enspire DBS Therapy System-Stroke-Product Description 26

Table 23: Enspire DBS Therapy System-Traumatic Brain Injury-Product Status 27

Table 24: Enspire DBS Therapy System-Traumatic Brain Injury-Product Description 27

Table 25: Vercise Deep Brain Stimulation System-Parkinson's Disease-Product Status 27

Table 26: Vercise Deep Brain Stimulation System-Parkinson's Disease-Product Description 28

Table 27: Boston Scientific Corp-Ongoing Clinical Trials Overview 28

Table 28: Vercise Deep Brain Stimulation System-Parkinson's Disease-Directional Lead: Investigation of Rotational Current Steering, Ease of Use of Clinical Effects Map, and Therapeutic Outcomes of Deep Brain Stimulation 29

Table 29: Vercise Deep Brain Stimulation System-Parkinson's Disease-Implantable Neurostimulator for the Treatment of Parkinson's Disease 29

Table 30: Vercise Deep Brain Stimulation System-Parkinson's Disease-Registry of Deep Brain Stimulation with the VERCISE System: Vercise DBS Registry 29

Table 31: Brainsway Ltd Pipeline Products & Ongoing Clinical Trials Overview 30

Table 32: Deep TMS System-Alzheimer's Disease-Product Status 30

Table 33: Deep TMS System-Alzheimer's Disease-Product Description 31

Table 34: Deep TMS System-Autism-Product Status 31

Table 35: Deep TMS System-Autism-Product Description 31

Table 36: Deep TMS System-Bipolar Disorder-Product Status 32

Table 37: Deep TMS System-Bipolar Disorder-Product Description 32

Table 38: Deep TMS System-Multiple Sclerosis-Product Status 32

Table 39: Deep TMS System-Multiple Sclerosis-Product Description 33

Table 40: Deep TMS System-Obsessive Compulsive Disorder-Product Status 33

Table 41: Deep TMS System-Obsessive Compulsive Disorder-Product Description 33

Table 42: Deep TMS System-PTSD-Product Status 34

Table 43: Deep TMS System-PTSD-Product Description 34

Table 44: Deep TMS System-Smoking Cessation-Product Status 34

Table 45: Deep TMS System-Smoking Cessation-Product Description 35

Table 46: Deep TMS System-Stroke-Product Status 35

Table 47: Deep TMS System-Stroke-Product Description 35

Table 48: Brainsway Ltd-Ongoing Clinical Trials Overview 36

Table 49: Deep TMS System-Bipolar Disorder-Evaluation Clinical, Cognitive and Safety in the Treatment of Bipolar Depression with H1-Coil Deep Transcranial Magnetic Stimulation 36

Table 50: Deep TMS System-Smoking Cessation-A Prospective, Double Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of the Deep Transcranial Magnetic Stimulation (DTMS) (with the H-ADD Coil) Intended as an Aid to Smoking Cessation 37

Table 51: Deep TMS System-PTSD-A Prospective, Double Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of the Brainsway (HAC-Coil) Deep Transcranial Magnetic Stimulation (DTMS) System for the Treatment of Post-traumatic Stress Disorder (PTSD) 38

Table 52: Deep TMS System-PTSD-Multi-center Investigational Device Exemption Study of Brainsway's Deep Transcranial Magnetic Stimulation for Treatment of Post Traumatic Stress Disorder 38

Table 53: Deep TMS System-Obsessive Compulsive Disorder-Tolerability, Safety and Efficacy of the HAC-coil Deep Transcranial Magnetic Stimulation in Medication Resistance Obsessive Compulsive Disorder (OCD) Subjects 39

Table 54: Cerene Biomedics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 40

Table 55: Implantable Cooling Therapy Device-Product Status 40

Table 56: Implantable Cooling Therapy Device-Product Description 40

Table 57: Cerevast Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 41

Table 58: Neurosonx SR-Product Status 41

Table 59: Neurosonx SR-Product Description 41

Table 60: Children's Hospital Boston Pipeline Products & Ongoing Clinical Trials Overview 42

Table 61: rTMS H-Coil-Product Status 42

Table 62: rTMS H-Coil-Product Description 42

Table 63: Cleveland Medical Devices Inc Pipeline Products & Ongoing Clinical Trials Overview 43

Table 64: ParkinTune-Product Status 43

Table 65: ParkinTune-Product Description 43

Table 66: Clinatec Pipeline Products & Ongoing Clinical Trials Overview 44

Table 67: Intracranial Deep Brain Stimulation Device-Product Status 44

Table 68: Intracranial Deep Brain Stimulation Device-Product Description 44

Table 69: Deep Brain Innovations, LLC Pipeline Products & Ongoing Clinical Trials Overview 45

Table 70: TOPS Device-Alzheimer's disease-Product Status 45

Table 71: TOPS Device-Alzheimer's disease-Product Description 45

Table 72: TOPS Device-Depression-Product Status 46

Table 73: TOPS Device-Depression-Product Description 46

Table 74: TOPS Device-Epilepsy-Product Status 46

Table 75: TOPS Device-Epilepsy-Product Description 47

Table 76: TOPS Device-Obesity-Product Status 47

Table 77: TOPS Device-Obesity-Product Description 47

Table 78: TOPS Device-Obsessive-Compulsive Disorder-Product Status 48

Table 79: TOPS Device-Obsessive-Compulsive Disorder-Product Description 48

Table 80: TOPS Device-Parkinson's disease-Product Status 48

Table 81: TOPS Device-Parkinson's disease-Product Description 49

Table 82: Duke University Pipeline Products & Ongoing Clinical Trials Overview 50

Table 83: DBS Electrode-Product Status 50

Table 84: DBS Electrode-Product Description 50

Table 85: Functional Neuromodulation Inc. Pipeline Products & Ongoing Clinical Trials Overview 51

Table 86: Deep Brain Stimulation-Mild Alzheimer's Disease-Product Status 51

Table 87: Deep Brain Stimulation-Mild Alzheimer's Disease-Product Description 51

Table 88: Functional Neuromodulation Inc.-Ongoing Clinical Trials Overview 52

Table 89: Deep Brain Stimulation-Mild Alzheimer's Disease-A Twelve Month Double-blind Randomized Controlled Feasibility Study to Evaluate the Safety, Efficacy and Tolerability of Deep Brain Stimulation of the Fornix (DBS-f) in Patients with Mild Probable Alzheimer's Disease 52

Table 90: Highland Instruments, Inc. Pipeline Products & Ongoing Clinical Trials Overview 53

Table 91: ESStim-Parkinson's Disease-Product Status 53

Table 92: ESStim-Parkinson's Disease-Product Description 53

Table 93: Massachusetts General Hospital Pipeline Products & Ongoing Clinical Trials Overview 54

Table 94: Deep Brain Stimulation Device-Product Status 54

Table 95: Deep Brain Stimulation Device-Product Description 54

Table 96: Deep Brain Stimulation System-Product Status 55

Table 97: Deep Brain Stimulation System-Product Description 55

Table 98: Massachusetts Institute of Technology Pipeline Products & Ongoing Clinical Trials Overview 56

Table 99: Implantable Micro-Cannula Device-Product Status 56

Table 100: Implantable Micro-Cannula Device-Product Description 56

Table 101: Mayo Clinic US Pipeline Products & Ongoing Clinical Trials Overview 57

Table 102: Sensor System-DBS-Product Status 57

Table 103: Sensor System-DBS-Product Description 57

Table 104: Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 58

Table 105: Intercept Patient Programmer For Activa PC-Refractory Epilepsy-Product Status 58

Table 106: Intercept Patient Programmer For Activa PC-Refractory Epilepsy-Product Description 59

Table 107: Reclaim Deep Brain Stimulation System-Depression-Product Status 59

Table 108: Reclaim Deep Brain Stimulation System-Depression-Product Description 59

Table 109: Sapiens DBS Field Steering System-Product Status 60

Table 110: Sapiens DBS Field Steering System-Product Description 60

Table 111: Medtronic plc-Ongoing Clinical Trials Overview 60

Table 112: Intercept Patient Programmer For Activa PC-Refractory Epilepsy-Medtronic Registry for Epilepsy (MORE) 61

Table 113: National Cheng-Kung University Hospital Pipeline Products & Ongoing Clinical Trials Overview 62

Table 114: Responsive Epilepsy Control System-On-Chip-Product Status 62

Table 115: Responsive Epilepsy Control System-On-Chip-Product Description 62

Table 116: NeuroPro Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview 63

Table 117: Deep Brain Stimulation-Product Status 63

Table 118: Deep Brain Stimulation-Product Description 63

Table 119: Neurosigma Inc Pipeline Products & Ongoing Clinical Trials Overview 64

Table 120: Deep Brain Stimulation System-Cachexia-Product Status 64

Table 121: Deep Brain Stimulation System-Cachexia-Product Description 64

Table 122: Deep Brain Stimulation System-Obesity-Product Status 65

Table 123: Deep Brain Stimulation System-Obesity-Product Description 65

Table 124: Newronika s.r.l. Pipeline Products & Ongoing Clinical Trials Overview 66

Table 125: Implantable Deep Brain Stimulation Device-Product Status 66

Table 126: Implantable Deep Brain Stimulation Device-Product Description 66

Table 127: Nuraleve Inc. Pipeline Products & Ongoing Clinical Trials Overview 67

Table 128: SmartStim M200 Device-Product Status 67

Table 129: SmartStim M200 Device-Product Description 67

Table 130: Soterix Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 68

Table 131: 11 tDCS Device-Product Status 68

Table 132: 11 tDCS Device-Product Description 69

Table 133: HD-tDCS Platform-Product Status 69

Table 134: HD-tDCS Platform-Product Description 70

Table 135: PainX tDCS System-Product Status 70

Table 136: PainX tDCS System-Product Description 71

Table 137: Soterix Medical Inc-Ongoing Clinical Trials Overview 72

Table 138: HD-tDCS Platform-Association of Transcranial Direct Current Stimulation (tDCS) with Gait Training with Partial Body Weight Support on the Robotic Device (Lokomat) for Treatment of Patients with Incomplete Spinal Cord Injury 74

Table 139: HD-tDCS Platform-High Definition Cathodal Transcranial Direct Current Stimulation for Treatment of Refractory Partial Onset Epilepsy 74

Table 140: HD-tDCS Platform-Targeted Transcranial Electrotherapy for Stroke Rehabilitation-Exploratory Trial on Aphasia 74

Table 141: 11 tDCS Device-Boston-Harvard Burn Injury Model System: Cortical Modulation with Transcranial Direct Current Stimulation (tDCS) for Neuropathic Symptoms Following Burn Injury 75

Table 142: 11 tDCS Device-Effects of Transcranial Direct Current Stimulation (tDCS) in Spoken and Written Production in Primary Progressive Aphasia (PPA) 75

Table 143: 11 tDCS Device-Escitalopram and Transcranial Direct Current Stimulation in Major Depressive Disorder: A Double-blind, Placebo-controlled, Randomized, Non-inferiority Trial 75

Table 144: 11 tDCS Device-Evaluating Anodal tDCS Preceding Aphasia Therapy 76

Table 145: 11 tDCS Device-Home-Administered Transcranial Direct Current Stimulation (tDCS) Treatment for Depression 76

Table 146: 11 tDCS Device-Neural Correlates of Pain-related Cognitive Processing in Chronic Pain of the Cornea: An ERP and Electrical Stimulation Study 76

Table 147: 11 tDCS Device-Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS) 77

Table 148: 11 tDCS Device-Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment 77

Table 149: 11 tDCS Device-Spaulding-Harvard Spinal Cord Injury (SH-SCI) Study: Effects of tDCS on Chronic Pain in Spinal Cord Injury 78

Table 150: 11 tDCS Device-tDCS and Aphasia Treatment 78

Table 151: 11 tDCS Device-The Influence of tDSC on the Arm and Hand Function in Stroke Patients 78

Table 152: 11 tDCS Device-Transcranial Direct Current Stimulation for Hallucinations in First-episode Schizophrenia 79

Table 153: 11 tDCS Device-Transcranial Direct Current Stimulation to Enhance Cognition in Mild Cognitive Impairment 79

Table 154: PainX tDCS System-Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees 80

Table 155: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 81

Table 156: Implantable Electrode-Epilepsy Surgery-Product Status 81

Table 157: Implantable Electrode-Epilepsy Surgery-Product Description 81

Table 158: Indigenous Deep Brain Stimulation Device-Product Status 82

Table 159: Indigenous Deep Brain Stimulation Device-Product Description 82

Table 160: St. Jude Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 83

Table 161: Libra Deep Brain Stimulation System-Depression-Product Status 83

Table 162: Libra Deep Brain Stimulation System-Depression-Product Description 84

Table 163: Next Generation Implantable DBS System-Primary Cell-Product Status 84

Table 164: Next Generation Implantable DBS System-Primary Cell-Product Description 84

Table 165: St. Jude Medical Inc-Ongoing Clinical Trials Overview 85

Table 166: Libra Deep Brain Stimulation System-Depression-A Clinical Evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression 85

Table 167: Libra Deep Brain Stimulation System-Depression-Deep Brain Stimulation for Treatment-Resistant Depression 85

Table 168: SUNY Downstate Medical Center Pipeline Products & Ongoing Clinical Trials Overview 86

Table 169: Low-Frequency Sine Wave Neurostimulation Therapy Device-Product Status 86

Table 170: Low-Frequency Sine Wave Neurostimulation Therapy Device-Product Description 86

Table 171: The University of Utah Pipeline Products & Ongoing Clinical Trials Overview 87

Table 172: DBS10k-Product Status 87

Table 173: DBS10k-Product Description 87

Table 174: Neural Recording Array-Product Status 88

Table 175: Neural Recording Array-Product Description 88

Table 176: University of California Los Angeles Pipeline Products & Ongoing Clinical Trials Overview 89

Table 177: Implantable Ultrasound Neuromodulation Device-Product Status 89

Table 178: Implantable Ultrasound Neuromodulation Device-Product Description 89

Table 179: Wireless Deep Brain Stimulating System-Product Status 90

Table 180: Wireless Deep Brain Stimulating System-Product Description 90

Table 181: University of Central Florida Pipeline Products & Ongoing Clinical Trials Overview 91

Table 182: Deep Brain Stimulation System-Product Status 91

Table 183: Deep Brain Stimulation System-Product Description 92

Table 184: University of Illinois Pipeline Products & Ongoing Clinical Trials Overview 93

Table 185: Wireless Deep Brain Stimulation System-Essential Tremor-Product Status 93

Table 186: Wireless Deep Brain Stimulation System-Essential Tremor-Product Description 94

Table 187: Wireless Deep Brain Stimulation System-Parkinson's Disease-Product Status 94

Table 188: Wireless Deep Brain Stimulation System-Parkinson's Disease-Product Description 94

Table 189: University of Michigan Pipeline Products & Ongoing Clinical Trials Overview 95

Table 190: Deep Brain Stimulation System-Product Status 95

Table 191: Deep Brain Stimulation System-Product Description 95

Table 192: University of Milan Pipeline Products & Ongoing Clinical Trials Overview 96

Table 193: Implantable Brain Pacemaker-Product Status 96

Table 194: Implantable Brain Pacemaker-Product Description 96

Table 195: University of Oxford Pipeline Products & Ongoing Clinical Trials Overview 97

Table 196: Adaptive Deep Brain Stimulation System-Product Status 97

Table 197: Adaptive Deep Brain Stimulation System-Product Description 97

Table 198: University of South Florida Pipeline Products & Ongoing Clinical Trials Overview 98

Table 199: Deep Brain Stimulator-Product Status 98

Table 200: Deep Brain Stimulator-Product Description 98

Table 201: Wedge Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 99

Table 202: SONS System-Product Status 99

Table 203: SONS System-Product Description 99

Table 204: Glossary 138

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Adaptive Neuromodulation GmbH, Aleva Neurotherapeutics SA, Boston Scientific Corp, Brainsway Ltd, Cerene Biomedics, Inc., Cerevast Therapeutics Inc, Children's Hospital Boston, Cleveland Medical Devices Inc, Clinatec, Deep Brain Innovations, LLC, Duke University, Functional Neuromodulation Inc., Highland Instruments, Inc., Massachusetts General Hospital, Massachusetts Institute of Technology, Mayo Clinic US, Medtronic plc, National Cheng-Kung University Hospital, NeuroPro Technologies Inc, Neurosigma Inc, Newronika s.r.l., Nuraleve Inc., Soterix Medical Inc, Sree Chitra Tirunal Institute for Medical Sciences & Technology, St. Jude Medical Inc, SUNY Downstate Medical Center, The University of Utah, University of California Los Angeles, University of Central Florida, University of Illinois, University of Michigan, University of Milan, University of Oxford, University of South Florida, Wedge Therapeutics

Adaptive Neuromodulation GmbH, CR-Capable Implant; Aleva Neurotherapeutics SA, directSTIM; Aleva Neurotherapeutics SA, spiderSTIM; Boston Scientific Corp, Directional Lead; Boston Scientific Corp, Enspire DBS Therapy System-Stroke; Boston Scientific Corp, Enspire DBS Therapy System-Traumatic Brain Injury; Boston Scientific Corp, Vercise Deep Brain Stimulation System-Parkinson's Disease; Brainsway Ltd, Deep TMS System-Alzheimer's Disease; Brainsway Ltd, Deep TMS System-Autism; Brainsway Ltd, Deep TMS System-Bipolar Disorder; Brainsway Ltd, Deep TMS System-Multiple Sclerosis; Brainsway Ltd, Deep TMS System-Obsessive Compulsive Disorder; Brainsway Ltd, Deep TMS System-PTSD; Brainsway Ltd, Deep TMS System-Smoking Cessation; Brainsway Ltd, Deep TMS System-Stroke; Cerene Biomedics, Inc., Implantable Cooling Therapy Device; Cerevast Therapeutics Inc, Neurosonx SR; Children's Hospital Boston, rTMS H-Coil; Cleveland Medical Devices Inc, ParkinTune; Clinatec, Intracranial Deep Brain Stimulation Device; Deep Brain Innovations, LLC, TOPS Device-Alzheimer's disease; Deep Brain Innovations, LLC, TOPS Device-Depression; Deep Brain Innovations, LLC, TOPS Device-Epilepsy; Deep Brain Innovations, LLC, TOPS Device-Obesity; Deep Brain Innovations, LLC, TOPS Device-Obsessive-Compulsive Disorder; Deep Brain Innovations, LLC, TOPS Device-Parkinson's disease; Duke University, DBS Electrode; Functional Neuromodulation Inc., Deep Brain Stimulation-Mild Alzheimer's Disease; Highland Instruments, Inc., ESStim-Parkinson's Disease; Massachusetts General Hospital, Deep Brain Stimulation Device; Massachusetts General Hospital, Deep Brain Stimulation System; Massachusetts Institute of Technology, Implantable Micro-Cannula Device; Mayo Clinic US, Sensor System-DBS; Medtronic plc, Intercept Patient Programmer For Activa PC-Refractory Epilepsy; Medtronic plc, Reclaim Deep Brain Stimulation System-Depression; Medtronic plc, Sapiens DBS Field Steering System; National Cheng-Kung University Hospital, Responsive Epilepsy Control System-On-Chip; NeuroPro Technologies Inc, Deep Brain Stimulation; Neurosigma Inc, Deep Brain Stimulation System-Cachexia; Neurosigma Inc, Deep Brain Stimulation System-Obesity; Newronika s.r.l., Implantable Deep Brain Stimulation Device; Nuraleve Inc., SmartStim M200 Device; Soterix Medical Inc, 11 tDCS Device; Soterix Medical Inc, HD-tDCS Platform; Soterix Medical Inc, PainX tDCS System; Sree Chitra Tirunal Institute for Medical Sciences &; Technology, Implantable Electrode-Epilepsy Surgery; Sree Chitra Tirunal Institute for Medical Sciences &; Technology, Indigenous Deep Brain Stimulation Device; St. Jude Medical Inc, Libra Deep Brain Stimulation System-Depression; St. Jude Medical Inc, Next Generation Implantable DBS System-Primary Cell; SUNY Downstate Medical Center, Low-Frequency Sine Wave Neurostimulation Therapy Device; The University of Utah, DBS10k; The University of Utah, Neural Recording Array; University of California Los Angeles, Implantable Ultrasound Neuromodulation Device; University of California Los Angeles, Wireless Deep Brain Stimulating System; University of Central Florida, Deep Brain Stimulation System; University of Illinois, Wireless Deep Brain Stimulation System-Essential Tremor; University of Illinois, Wireless Deep Brain Stimulation System-Parkinson's Disease; University of Michigan, Deep Brain Stimulation System; University of Milan, Implantable Brain Pacemaker; University of Oxford, Adaptive Deep Brain Stimulation System; University of South Florida, Deep Brain Stimulator; Wedge Therapeutics, SONS System


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