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Metastatic Biliary Tract Cancer-Pipeline Review, H1 2015

Metastatic Biliary Tract Cancer-Pipeline Review, H1 2015


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Executive Summary

Metastatic Biliary Tract Cancer-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Metastatic Biliary Tract Cancer-Pipeline Review, H1 2015', provides an overview of the Metastatic Biliary Tract Cancer's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Metastatic Biliary Tract Cancer, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Metastatic Biliary Tract Cancer and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Metastatic Biliary Tract Cancer

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Metastatic Biliary Tract Cancer and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Metastatic Biliary Tract Cancer products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Metastatic Biliary Tract Cancer pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Metastatic Biliary Tract Cancer

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Metastatic Biliary Tract Cancer pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 3

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Metastatic Biliary Tract Cancer Overview 6

Therapeutics Development 7

Pipeline Products for Metastatic Biliary Tract Cancer-Overview 7

Pipeline Products for Metastatic Biliary Tract Cancer-Comparative Analysis 8

Metastatic Biliary Tract Cancer-Therapeutics under Development by Companies 9

Metastatic Biliary Tract Cancer-Pipeline Products Glance 10

Clinical Stage Products 10

Metastatic Biliary Tract Cancer-Products under Development by Companies 11

Metastatic Biliary Tract Cancer-Companies Involved in Therapeutics Development 12

AstraZeneca PLC 12

GlaxoSmithKline plc 13

Novartis AG 14

OncoTherapy Science, Inc. 15

Metastatic Biliary Tract Cancer-Therapeutics Assessment 16

Assessment by Monotherapy Products 16

Assessment by Combination Products 17

Assessment by Target 18

Assessment by Mechanism of Action 20

Assessment by Route of Administration 22

Assessment by Molecule Type 23

Drug Profiles 25

(dabrafenib mesylate + trametinib dimethyl sulfoxide)-Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

binimetinib-Drug Profile 27

Product Description 27

Mechanism of Action 27

R&D Progress 27

OCV-C01-Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

selumetinib sulfate-Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

trametinib dimethyl sulfoxide-Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

Metastatic Biliary Tract Cancer-Recent Pipeline Updates 38

Metastatic Biliary Tract Cancer-Discontinued Products 47

Appendix 48

Methodology 48

Coverage 48

Secondary Research 48

Primary Research 48

Expert Panel Validation 48

Contact Us 48

Disclaimer 49

List of Tables

Number of Products under Development for Metastatic Biliary Tract Cancer, H1 2015 7

Number of Products under Development for Metastatic Biliary Tract Cancer-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Products under Development by Companies, H1 2015 11

Metastatic Biliary Tract Cancer-Pipeline by AstraZeneca PLC, H1 2015 12

Metastatic Biliary Tract Cancer-Pipeline by GlaxoSmithKline plc, H1 2015 13

Metastatic Biliary Tract Cancer-Pipeline by Novartis AG, H1 2015 14

Metastatic Biliary Tract Cancer-Pipeline by OncoTherapy Science, Inc., H1 2015 15

Assessment by Monotherapy Products, H1 2015 16

Assessment by Combination Products, H1 2015 17

Number of Products by Stage and Target, H1 2015 19

Number of Products by Stage and Mechanism of Action, H1 2015 21

Number of Products by Stage and Route of Administration, H1 2015 22

Number of Products by Stage and Molecule Type, H1 2015 24

Metastatic Biliary Tract Cancer Therapeutics-Recent Pipeline Updates, H1 2015 38

Metastatic Biliary Tract Cancer-Discontinued Products, H1 2015 47

List of Figures

Number of Products under Development for Metastatic Biliary Tract Cancer, H1 2015 7

Number of Products under Development for Metastatic Biliary Tract Cancer-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Assessment by Monotherapy Products, H1 2015 16

Number of Products by Top 10 Targets, H1 2015 18

Number of Products by Stage and Top 10 Targets, H1 2015 19

Number of Products by Top 10 Mechanism of Actions, H1 2015 20

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 21

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 22

Number of Products by Top 10 Molecule Types, H1 2015 23

Number of Products by Stage and Top 10 Molecule Types, H1 2015 24

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AstraZeneca PLC

GlaxoSmithKline plc

Novartis AG

OncoTherapy Science, Inc.

Metastatic Biliary Tract Cancer Therapeutic Products under Development, Key Players in Metastatic Biliary Tract Cancer Therapeutics, Metastatic Biliary Tract Cancer Pipeline Overview, Metastatic Biliary Tract Cancer Pipeline, Metastatic Biliary Tract Cancer Pipeline Assessment


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