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Peripheral Neuropathy (Sensory Neuropathy)-Pipeline Review, H1 2015

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline Review, H1 2015


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Executive Summary

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Peripheral Neuropathy (Sensory Neuropathy)-Pipeline Review, H1 2015', provides an overview of the Peripheral Neuropathy (Sensory Neuropathy)'s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Peripheral Neuropathy (Sensory Neuropathy), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Peripheral Neuropathy (Sensory Neuropathy) and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Peripheral Neuropathy (Sensory Neuropathy)

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Peripheral Neuropathy (Sensory Neuropathy) and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Peripheral Neuropathy (Sensory Neuropathy) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Peripheral Neuropathy (Sensory Neuropathy) pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Peripheral Neuropathy (Sensory Neuropathy)

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Peripheral Neuropathy (Sensory Neuropathy) pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 6

Introduction 7

Global Markets Direct Report Coverage 7

Peripheral Neuropathy (Sensory Neuropathy) Overview 8

Therapeutics Development 9

Pipeline Products for Peripheral Neuropathy (Sensory Neuropathy)-Overview 9

Pipeline Products for Peripheral Neuropathy (Sensory Neuropathy)-Comparative Analysis 10

Peripheral Neuropathy (Sensory Neuropathy)-Therapeutics under Development by Companies 11

Peripheral Neuropathy (Sensory Neuropathy)-Therapeutics under Investigation by Universities/Institutes 13

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline Products Glance 14

Late Stage Products 14

Clinical Stage Products 15

Early Stage Products 16

Peripheral Neuropathy (Sensory Neuropathy)-Products under Development by Companies 17

Peripheral Neuropathy (Sensory Neuropathy)-Products under Investigation by Universities/Institutes 18

Peripheral Neuropathy (Sensory Neuropathy)-Companies Involved in Therapeutics Development 19

Acorda Therapeutics, Inc. 19

aTyr Pharma, Inc. 20

GeNeuro SA 21

INSYS Therapeutics, Inc. 22

Mitsubishi Tanabe Pharma Corporation 23

Neuren Pharmaceuticals Limited 24

Pfizer Inc. 25

RegeneRx Biopharmaceuticals, Inc. 26

Takeda Pharmaceutical Company Limited 27

Teijin Pharma Limited 28

Peripheral Neuropathy (Sensory Neuropathy)-Therapeutics Assessment 29

Assessment by Monotherapy Products 29

Assessment by Target 30

Assessment by Mechanism of Action 32

Assessment by Route of Administration 34

Assessment by Molecule Type 36

Drug Profiles 38

cannabidiol-Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

fingolimod hydrochloride-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

GL-2045-Drug Profile 42

Product Description 42

Mechanism of Action 42

R&D Progress 42

immune globulin (human)-Drug Profile 43

Product Description 43

Mechanism of Action 43

R&D Progress 43

immune globulin (human)-Drug Profile 44

Product Description 44

Mechanism of Action 44

R&D Progress 44

Monoclonal Antibody for CIDP-Drug Profile 46

Product Description 46

Mechanism of Action 46

R&D Progress 46

NNZ-2591-Drug Profile 47

Product Description 47

Mechanism of Action 47

R&D Progress 47

NP-1998-Drug Profile 49

Product Description 49

Mechanism of Action 49

R&D Progress 49

NRP-2945-Drug Profile 51

Product Description 51

Mechanism of Action 51

R&D Progress 51

Peptide to Activate GLP1R for CNS, Metabolic Disorders and Head Trauma-Drug Profile 53

Product Description 53

Mechanism of Action 53

R&D Progress 53

Peptides for Neuropathic Pain and Peripheral Neuropathy-Drug Profile 54

Product Description 54

Mechanism of Action 54

R&D Progress 54

Peptides to Activate GLP-1 Receptor for CNS Disorders and Head Trauma-Drug Profile 55

Product Description 55

Mechanism of Action 55

R&D Progress 55

Proteins for Inflammation, Hematological, Metabolic, Oncology, Neurodegenerative and Cardiovascular Disorder-Drug Profile 56

Product Description 56

Mechanism of Action 56

R&D Progress 56

RGN-352-Drug Profile 57

Product Description 57

Mechanism of Action 57

R&D Progress 57

Small Molecules for Peripheral Neuropathy and Amyotrophic Lateral Sclerosis-Drug Profile 59

Product Description 59

Mechanism of Action 59

R&D Progress 59

Small Molecules to Inhibit Cysteine Protease and Caspases for Oncology, Immunology, Infectious and CNS Disorders-Drug Profile 60

Product Description 60

Mechanism of Action 60

R&D Progress 60

Synthetic Peptides for Peripheral Neuropathy-Drug Profile 61

Product Description 61

Mechanism of Action 61

R&D Progress 61

Peripheral Neuropathy (Sensory Neuropathy)-Recent Pipeline Updates 62

Peripheral Neuropathy (Sensory Neuropathy)-Dormant Projects 72

Peripheral Neuropathy (Sensory Neuropathy)-Discontinued Products 73

Peripheral Neuropathy (Sensory Neuropathy)-Product Development Milestones 74

Featured News & Press Releases 74

Jul 12, 2013: Neuren Receives Notice of Allowance for New Patent 74

Appendix 75

Methodology 75

Coverage 75

Secondary Research 75

Primary Research 75

Expert Panel Validation 75

Contact Us 76

Disclaimer 76

List of Tables

Number of Products under Development for Peripheral Neuropathy (Sensory Neuropathy), H1 2015 9

Number of Products under Development for Peripheral Neuropathy (Sensory Neuropathy)-Comparative Analysis, H1 2015 10

Number of Products under Development by Companies, H1 2015 12

Number of Products under Investigation by Universities/Institutes, H1 2015 13

Comparative Analysis by Late Stage Development, H1 2015 14

Comparative Analysis by Clinical Stage Development, H1 2015 15

Comparative Analysis by Early Stage Development, H1 2015 16

Products under Development by Companies, H1 2015 17

Products under Investigation by Universities/Institutes, H1 2015 18

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Acorda Therapeutics, Inc., H1 2015 19

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by aTyr Pharma, Inc., H1 2015 20

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by GeNeuro SA, H1 2015 21

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by INSYS Therapeutics, Inc., H1 2015 22

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Mitsubishi Tanabe Pharma Corporation, H1 2015 23

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Neuren Pharmaceuticals Limited, H1 2015 24

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Pfizer Inc., H1 2015 25

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by RegeneRx Biopharmaceuticals, Inc., H1 2015 26

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 27

Peripheral Neuropathy (Sensory Neuropathy)-Pipeline by Teijin Pharma Limited, H1 2015 28

Assessment by Monotherapy Products, H1 2015 29

Number of Products by Stage and Target, H1 2015 31

Number of Products by Stage and Mechanism of Action, H1 2015 33

Number of Products by Stage and Route of Administration, H1 2015 35

Number of Products by Stage and Molecule Type, H1 2015 37

Peripheral Neuropathy (Sensory Neuropathy) Therapeutics-Recent Pipeline Updates, H1 2015 62

Peripheral Neuropathy (Sensory Neuropathy)-Dormant Projects, H1 2015 72

Peripheral Neuropathy (Sensory Neuropathy)-Discontinued Products, H1 2015 73

List of Figures

Number of Products under Development for Peripheral Neuropathy (Sensory Neuropathy), H1 2015 9

Number of Products under Development for Peripheral Neuropathy (Sensory Neuropathy)-Comparative Analysis, H1 2015 10

Number of Products under Development by Companies, H1 2015 11

Comparative Analysis by Clinical Stage Development, H1 2015 15

Comparative Analysis by Early Stage Products, H1 2015 16

Assessment by Monotherapy Products, H1 2015 29

Number of Products by Top 10 Targets, H1 2015 30

Number of Products by Stage and Top 10 Targets, H1 2015 31

Number of Products by Top 10 Mechanism of Actions, H1 2015 32

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 33

Number of Products by Top 10 Routes of Administration, H1 2015 34

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 35

Number of Products by Top 10 Molecule Types, H1 2015 36

Number of Products by Stage and Top 10 Molecule Types, H1 2015 37

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Acorda Therapeutics, Inc.

aTyr Pharma, Inc.

GeNeuro SA

INSYS Therapeutics, Inc.

Mitsubishi Tanabe Pharma Corporation

Neuren Pharmaceuticals Limited

Pfizer Inc.

RegeneRx Biopharmaceuticals, Inc.

Takeda Pharmaceutical Company Limited

Teijin Pharma Limited

Peripheral Neuropathy (Sensory Neuropathy) Therapeutic Products under Development, Key Players in Peripheral Neuropathy (Sensory Neuropathy) Therapeutics, Peripheral Neuropathy (Sensory Neuropathy) Pipeline Overview, Peripheral Neuropathy (Sensory Neuropathy) Pipeline, Peripheral Neuropathy (Sensory Neuropathy) Pipeline Assessment


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