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Renal Insufficiency-Pipeline Review, H1 2015

Renal Insufficiency-Pipeline Review, H1 2015


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Executive Summary

Renal Insufficiency-Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Renal Insufficiency-Pipeline Review, H1 2015', provides an overview of the Renal Insufficiency's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Renal Insufficiency, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Renal Insufficiency and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

The report provides a snapshot of the global therapeutic landscape of Renal Insufficiency

The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in the therapeutics development for Renal Insufficiency and enlists all their major and minor projects

The report summarizes all the dormant and discontinued pipeline projects

A review of the Renal Insufficiency products under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages

A detailed assessment of monotherapy and combination therapy pipeline projects

Coverage of the Renal Insufficiency pipeline on the basis of target, MoA, route of administration and molecule type

Latest news and deals relating related to pipeline products

Reasons To Buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Develop strategic initiatives by understanding the focus areas of leading companies

Identify and understand important and diverse types of therapeutics under development for Renal Insufficiency

Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline

Devise corrective measures for pipeline projects by understanding Renal Insufficiency pipeline depth and focus of Indication therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Renal Insufficiency Overview 6

Therapeutics Development 7

Pipeline Products for Renal Insufficiency-Overview 7

Pipeline Products for Renal Insufficiency-Comparative Analysis 8

Renal Insufficiency-Therapeutics under Development by Companies 9

Renal Insufficiency-Pipeline Products Glance 10

Clinical Stage Products 10

Renal Insufficiency-Products under Development by Companies 11

Renal Insufficiency-Companies Involved in Therapeutics Development 12

Boehringer Ingelheim GmbH 12

Elcelyx Therapeutics, Inc. 13

Nippon Zoki Pharmaceutical Co., Ltd. 14

Novartis AG 15

Shire Plc 16

The Medicines Company 17

Renal Insufficiency-Therapeutics Assessment 18

Assessment by Monotherapy Products 18

Assessment by Combination Products 19

Assessment by Target 20

Assessment by Mechanism of Action 22

Assessment by Route of Administration 24

Assessment by Molecule Type 26

Drug Profiles 28

(meropenem+ RPX-7009)-Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

afatinib-Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

BHQ-880-Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

LHW-090-Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

metformin hydrochloride DR-Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

metformin hydrochloride enteric-coated-Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

NZ-419-Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

SHP-627-Drug Profile 41

Product Description 41

Mechanism of Action 41

R&D Progress 41

Renal Insufficiency-Recent Pipeline Updates 42

Renal Insufficiency-Dormant Projects 51

Renal Insufficiency-Discontinued Products 52

Appendix 53

Methodology 53

Coverage 53

Secondary Research 53

Primary Research 53

Expert Panel Validation 53

Contact Us 53

Disclaimer 54

List of Tables

Number of Products under Development for Renal Insufficiency, H1 2015 7

Number of Products under Development for Renal Insufficiency-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Products under Development by Companies, H1 2015 11

Renal Insufficiency-Pipeline by Boehringer Ingelheim GmbH, H1 2015 12

Renal Insufficiency-Pipeline by Elcelyx Therapeutics, Inc., H1 2015 13

Renal Insufficiency-Pipeline by Nippon Zoki Pharmaceutical Co., Ltd., H1 2015 14

Renal Insufficiency-Pipeline by Novartis AG, H1 2015 15

Renal Insufficiency-Pipeline by Shire Plc, H1 2015 16

Renal Insufficiency-Pipeline by The Medicines Company, H1 2015 17

Assessment by Monotherapy Products, H1 2015 18

Assessment by Combination Products, H1 2015 19

Number of Products by Stage and Target, H1 2015 21

Number of Products by Stage and Mechanism of Action, H1 2015 23

Number of Products by Stage and Route of Administration, H1 2015 25

Number of Products by Stage and Molecule Type, H1 2015 27

Renal Insufficiency Therapeutics-Recent Pipeline Updates, H1 2015 42

Renal Insufficiency-Dormant Projects, H1 2015 51

Renal Insufficiency-Discontinued Products, H1 2015 52

List of Figures

Number of Products under Development for Renal Insufficiency, H1 2015 7

Number of Products under Development for Renal Insufficiency-Comparative Analysis, H1 2015 8

Number of Products under Development by Companies, H1 2015 9

Comparative Analysis by Clinical Stage Development, H1 2015 10

Assessment by Monotherapy Products, H1 2015 18

Number of Products by Top 10 Targets, H1 2015 20

Number of Products by Stage and Top 10 Targets, H1 2015 20

Number of Products by Top 10 Mechanism of Actions, H1 2015 22

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 22

Number of Products by Top 10 Routes of Administration, H1 2015 24

Number of Products by Stage and Top 10 Routes of Administration, H1 2015 25

Number of Products by Top 10 Molecule Types, H1 2015 26

Number of Products by Stage and Top 10 Molecule Types, H1 2015 27

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Boehringer Ingelheim GmbH

Elcelyx Therapeutics, Inc.

Nippon Zoki Pharmaceutical Co., Ltd.

Novartis AG

Shire Plc

The Medicines Company

Renal Insufficiency Therapeutic Products under Development, Key Players in Renal Insufficiency Therapeutics, Renal Insufficiency Pipeline Overview, Renal Insufficiency Pipeline, Renal Insufficiency Pipeline Assessment


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